Obesity trials in United States

In United States 744 Also abroad 1939

744 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Where
Albuquerque, Aurora, Austin, Birmingham, Bridgeport, Canoga Park, Chesterfield, Columbia, Corpus Christi, Cullman, Dallas, Daytona Beach, Delray Beach, Dunwoody, Eatontown, Escondido, Fargo, Fleming Island, Fort Worth, Greenbrae, Greensboro, Hamden, Honolulu, Houston, Indianapolis, Inverness, Jacksonville, Lawrenceville, Lima, Long Beach, Long Island City, Los Alamitos, Los Angeles, Macon, Mesquite, Metairie, Miami, Monroe, Morehead City, Mt. Dora, Mt. Pleasant, New Bedford, Ogden, Pembroke Pines, Pittsburgh, Plano, Portland, San Antonio, Sandy City, Santa Clarita, Skokie, Springfield, Spring Valley, Tucson, Uniontown, Walnut Creek, Warren Township, Wilmington, Winter Park
Age
18 years and over
People
1,035 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07282600 · EU 2025-523658-15-00
Phase 3Taking people
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
Where
Ammon, Bellaire, Brooklyn, Buffalo, Burlington, Charlottesville, Chicago, Colorado Springs, Decatur, DeSoto, Evansville, Fort Worth, Fountain Valley, Houston, Jacksonville, Kirkland, Long Island City, Louisville, Mesa, Mobile, Newton, Phoenix, Plymouth Meeting, Quincy, Rochester, San Antonio, Santa Ana, Shavano Park, South Jordan, Spring Valley, St. Petersburg, Tucson, Tulsa, Walnut Creek, Weslaco, Winter Park, Woodstock
Age
18 years and over
People
900 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07353931 · EU 2025-523768-19-00
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
Where
Albuquerque, Aurora, Austin, Bowie, Buffalo, Cincinnati, Columbia, Cullman, Las Vegas, Lawrenceville, Long Beach, Los Alamitos, Maplewood, Miami, Pensacola, Riverside, San Antonio, Shavano Park, Shreveport, Snellville, Southfield, St Louis
Age
18 years and over
People
800 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07369011 · EU 2025-523769-11-00
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Where
Atlantis, Birmingham, Boston, Bridgeport, Chapel Hill, Chesterfield, Chicago, Cincinnati, Columbia, Dallas, Doral, Dunwoody, Fleming Island, Gainesville, Greensboro, Houston, Idaho Falls, Irvine, Jacksonville, Kingwood, La Jolla, La Mesa, Lexington, Lima, Miami, Mission, Missouri City, Monroe, Morehead City, Myrtle Beach, New Haven, New York, Phoenix, Pittsburgh, Rolling Hills Estates, Sacramento, Saint Augustine, San Antonio, San Diego, Santa Ana, Scottsdale, Shavano Park, Southfield, Topeka, Troy, Tucson, Tustin, Waltham, Waterbury, Weslaco, West Des Moines, West Palm Beach, Wilmington, Wylie
Age
18 years and over
People
900 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07392190 · EU 2025-523659-73-00
No phaseTaking people
Confident Moves Intervention Efficacy Trial: Obesity Care Settings
Where
Des Moines
Age
18 years to 64 years
People
348
Run by
Iowa State University
See details and how to joinNCT07623772
Phase 1Taking people
Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use Outcomes
Where
New Haven
Age
18 years to 68 years
People
90
Run by
Yale University
See details and how to joinNCT07772960
No phaseTaking people
Effects of Dietary Supplements on Muscle Mass and Function While Using GLP-1 Medication
Where
Los Angeles
Age
18 years and over
People
75
Run by
University of California, Los Angeles
See details and how to joinNCT07806838
Phase 3Taking people
Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)
Where
Atlanta, Austin, Baltimore, Boston, Buffalo, Chapel Hill, Charleston, Chicago, Cincinnati, Cleveland, Colorado Springs, Columbus, Corpus Christi, Durham, Grand Rapids, Houston, Indianapolis, Loma Linda, Los Angeles, Louisville, Minneapolis, Morehead City, Nashville, New Haven, Oklahoma City, Omaha, Orange, Orlando, Oxnard, Richmond, Rochester, Saint Paul, Seattle, St. Petersburg, Tacoma, Tucson
Age
6 years to 11 years
People
150 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07817875 · EU 2025-522020-27-00
No phaseNot yet taking people in United States
Stearic Acid and Endothelial Function
Where
Tallahassee
Age
40 years to 70 years
People
40
Run by
Florida State University
See details and how to joinNCT07831603
Phase 3Taking people
A Study of EloraTZP in Adult Participants With Obesity or Overweight and Type 2 Diabetes
Where
Arlington, Aurora, Austin, Dalton, Eunice, Fort Worth, Honolulu, Houston, Indianapolis, Los Alamitos, Los Angeles, Marrero, Midland, Mission, New York, Pembroke Pines, Redmond, San Antonio, St Louis, Tucson, Tyler, Warren Township, Weston
Age
18 years and over
People
1,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07881458 · EU 2026-527230-31-00
Phase 1Not yet taking people in United States
A Study of LY4247147 in Participants With Obesity or Overweight Who Are Otherwise Healthy
Where
Lenexa, Salt Lake City
Age
18 years to 65 years
People
108 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07915245
Phase 3Taking people
A Study to Learn About Berobenatide Given Once Weekly in Adults With Knee Osteoarthritis and Overweight or Obesity With or Without Type 2 Diabetes (VESPER-OA 2)
Where
Birmingham, Miami, Shelby, Tucson
Age
18 years and over
People
756
Run by
Pfizer
See details and how to joinNCT07915609 · EU 2026-527180-15-00
Phase 1Not yet taking people in United States
Brain Dopamine Dynamics in Obesity
Where
New Haven
Age
50 years to 65 years
People
100
Run by
Yale University
See details and how to joinNCT07915986
No phaseTaking people
Synchronous vs Asynchronous Remotely Delivered Lifestyle Interventions
Where
Storrs
Age
18 years to 65 years
People
378
Run by
University of Connecticut
See details and how to joinNCT06393725
Phase 2Taking people
A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
Where
Altamonte Springs, Buffalo, Cincinnati, Cutler Bay, Cypress, Dearborn, Foxborough, Glendora, Houston, Huntsville, Indianapolis, Kingwood, Las Vegas, Lombard, Maitland, Manassas, McKinney, North Charleston, Ogden, Olive Branch, Orlando, Reston, The Bronx, Tucson, West Chester, Woodstock, Yardley
Age
18 years and over
People
120 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07783802
Phase 4Not yet taking people in United States
Comparing Different Medication Regimens to Maintaining Weight Loss Among Adults With Obesity Using GLP-1s
Where
Pittsburgh
Age
18 years and over
People
60
Run by
Jing Luo
See details and how to joinNCT07832084
Phase 3Not yet taking people in United States
A Study of EloraTZP in Adult Participants With Obesity Without Type 2 Diabetes
Where
Albuquerque, Arlington, Atlantis, Baltimore, Bellaire, Boston, Chapel Hill, Chicago, Covina, Dallas, Dalton, Dunwoody, Euless, Eunice, Greensboro, Honolulu, Houston, Indianapolis, Kingwood, Las Vegas, Long Island City, Los Angeles, Maitland, Memphis, Mesa, Metairie, Miami, New Haven, Newport News, New York, Norfolk, Philadelphia, Plymouth Meeting, Raleigh, Ridgeland, Rolling Hills Estates, San Antonio, San Diego, Santa Ana, Scottsdale, Shavano Park, Stockbridge, Tamarac, Tampa, Tucson, Tyler, Union City, West Valley City
Age
18 years and over
People
2,115 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07881432 · EU 2026-526047-34-00
Phase 2Not yet taking people in United States
A Study to Investigate the Effect of LY4086940 Versus Placebo in Participants With Obesity or Overweight and Without Type 2 Diabetes
Where
Amherst, Ammon, Austin, Chandler, Chicago, Cincinnati, City of Saint Peters, Dallas, Danville, Greenbrae, Greenville, Huntington Park, Las Vegas, Miami, Miami Lakes, Monroe, Morehead City, Nashville, Needham, New Bedford, New Bern, New Port Richey, Orlando, Rochester, Rolling Hills Estates, San Antonio, Scottsdale, Southfield, Springfield, Stamford, The Villages, Topeka, Troy, Tucson, Walnut Creek, Wenatchee, Weslaco, West Des Moines
Age
18 years to 75 years
People
460 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07890376
Phase 3Not yet taking people in United States
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk
Where
Altamonte Springs, Amarillo, Apache Junction, Arlington, Arlington Heights, Augusta, Baltimore, Birmingham, Brandon, Cincinnati, Corvallis, Covina, Cutler Bay, Dallas, East Providence, El Paso, Escondido, Exton, Fleming Island, Fort Worth, Franklin, Gilbert, Greenfield, Honolulu, Houston, Humble, Huntsville, Jacksonville, Lancaster, Las Vegas, Leesburg, Long Beach, Longview, McAllen, McKinney, Media, Miami, Morehead City, Nashua, New Bedford, Norfolk, Northridge, Ogden, Oxnard, Pasadena, Pembroke Pines, Phoenix, Port Charlotte, Redmond, Richmond, Ridgeland, Rochester, Saint Joseph, San Antonio, San Diego, Santa Clarita, Southfield, Springfield, Surprise, Tinley Park, Waterbury, Westlake Village, Wilmington, Wylie
Age
45 years to 64 years
People
3,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07900633 · EU 2026-525919-14-00
No phaseNot yet taking people in United States
Clinical Research Trial to Study Insulin Sensitivity Using Automated Glucose Clamp Technology
Where
Webster
Age
18 years to 65 years
People
50
Run by
Profil Institut für Stoffwechselforschung GmbH
See details and how to joinNCT07913698
No phaseTaking people
Early Tracking of Childhood Health Determinants (ETCHED) Study
Where
Phoenix
Age
1 day to 99 years
People
1,500
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT03481829
No phaseTaking people
Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat Change
Where
Bethesda
Age
18 years to 50 years
People
42
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT06325722
No phaseTaking people
Pregnancy 24/7 Offspring Study
Where
Iowa City, Morgantown, Pittsburgh
Age
0 years to 47 years
People
800
Run by
Kara Whitaker
See details and how to joinNCT07172880
No phaseTaking people
Time Restricted Eating for WeIght LoSs MainTenance-2
Where
New York
Age
25 years to 65 years
People
110
Run by
NYU Langone Health
See details and how to joinNCT07190170
Phase 1Taking people
Comparing the Extent to Which Maridebart Cafraglutide is Made Available in the Body of Participants Living With Overweight or Obesity After Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA)
Where
Dallas, Daytona Beach, Hialeah, Knoxville, Lexington, Madison, Maitland, Montclair, Phoenix
Age
18 years to 70 years
People
180
Run by
Amgen
See details and how to joinNCT07908316