Head and neck cancer: trials for referral
1026 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Head and neck cancer·What we know·Glossary·Tumour board sheet
Where the open trials are
Type a city to sort by distance. The distance is worked out in your browser; the city is not sent anywhere.
400 trials shown · Showing the 400 most recently updated of 1026 open trials.
Phase 1/21 site
RecruitingUnited States
NCT07667400
Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer
National Cancer Institute (NCI)
Registry updated 10 Nov 2026
Registry record: ClinicalTrials.govPhase 127 sites
RecruitingSpain, Georgia, United States
NCT07503808
A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types
IDEAYA Biosciences
Registry updated 10 Nov 2026
Registry record: ClinicalTrials.govPhase 1/24 sites
RecruitingUnited States
NCT06319963
A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer
Theravectys S.A.
Registry updated 10 Nov 2026
Registry record: ClinicalTrials.govPhase 1/25 sites
RecruitingRussia
NCT07292168
A Phase 1b/2 Study of the Safety and Efficacy of the Monoclonal Antibody OM-RCA-01 in Patients With Metastatic Tumors Expressing Fibroblast Growth Factor Receptor 1
Kidney Cancer Research Bureau
Registry updated 10 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingUnited States
NCT07631650
Bevonescein for Improved Intraoperative Nerve Visualization to Improve Voice Outcomes in Thyroidectomy Patients
Matthew Spector
Registry updated 10 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingUnited States
NCT07926906
Removing the Planning Tumor Volume From Radiation Therapy for the Treatment of Head and Neck Squamous Cell Carcinoma
City of Hope Medical Center
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
Not yet recruitingUnited States
NCT07923877
Induction Chemoimmunotherapy to Prevent Laryngectomy in Advanced Laryngeal Cancer and Hypopharyngeal Cancer
Mayo Clinic
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingUnited States
NCT07825597
Indocyanine Green With Near Infrared Imaging for Intraoperative Visualization of Head and Neck Squamous Cell Carcinoma
Washington University School of Medicine
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 41 site
RecruitingSlovenia
NCT07922759
Lidocaine Infiltration and Neuroimmunomodulation in Head and Neck Cancer Surgery
University Medical Centre Ljubljana
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingUnited States
NCT07783581
Proton Spatially Fractionated Radiotherapy or Photon Stereotactic Body Radiotherapy in Combination With Pembrolizumab Before Surgery for the Treatment of Locally Advanced and Radiation-Naive Locoregionally Recurrent Oral Cavity Cancer, OSPRI Trial
Mayo Clinic
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingChina
NCT07339774
Traditional Chinese Medicine Preparation Alleviates Radiotherapy-induced Oral Mucositis in Head and Neck Cancer Patients.
West China Hospital
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govPhase 24 sites
RecruitingUnited States
NCT07418034
A Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minimal Risk and Primary Site Disease (SAVED)
University of Maryland, Baltimore
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govPhase 3202 sites
RecruitingUnited States
NCT06589804
Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment
National Cancer Institute (NCI)
Pre-treatment window Registry sentence: “Previously untreated for recurrent and/or metastatic disease incurable by local therapies.”
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govPhase 1/260 sites
RecruitingSouth Korea, Singapore, Taiwan, United States
NCT04198766
Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
Inhibrx Biosciences, Inc
Pre-treatment window Registry sentence: “For Cohort F8, subjects must have previously untreated, histologically confirmed Stage II, IIIA or IIIB (T3-4N2) NSCLC.”
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govPhase 130 sites
RecruitingCanada, China, Spain, United Kingdom, Puerto Rico, United States
NCT07090499
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
Pfizer
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 1/20 sites
Not yet recruiting
NCT07920289
Intravenously Administered PROMITIL Combined With Radiotherapy in Patients With Cisplatin-Ineligible Head and Neck Cancer Patients
Assuta Ashdod Hospital
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingPakistan
NCT07919444
Effectiveness of Phenotype-based Pain Management Guidelines for Head and Neck Cancer Related Pain: a Pilot Study
Shaukat Khanum Memorial Cancer Hospital & Research Centre
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 11 site
RecruitingUnited States
NCT06096038
Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC
UNC Lineberger Comprehensive Cancer Center
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 24 sites
Not yet recruitingChina
NCT07915258
Becotatug Vedotin Plus Pucotenlimab in Locally Advanced Head and Neck Squamous Cell Carcinoma With Suboptimal Response to Induction Immunochemotherapy
Sun Yat-sen University
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 1/213 sites
RecruitingPuerto Rico, United States
NCT03556228
VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
VM Oncology, LLC
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 112 sites
RecruitingUnited States
NCT06150664
A Phase 1 of CTX-8371 in Patients With Advanced Malignancies
Compass Therapeutics
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 139 sites
RecruitingAustralia, China, Spain, France, United Kingdom, Japan
NCT06465069
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Eli Lilly and Company
Pre-treatment window Registry sentence: “Cohort D: Treatment-naive for locally advanced or metastatic urothelial cancer.”
Registry updated 4 Nov 2026 · The registries disagree on the status
Registry record: ClinicalTrials.govEarly Phase 11 site
RecruitingUnited States
NCT06914999
PET/CT Assessment of Radiation-Induced Vascular Complications in Head and Neck Cancer
Emory University
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT07756684
Feasibility of Cough Skill Training in Individuals With Head and Neck Cancer
Boston University Charles River Campus
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 3216 sites
RecruitingUnited States
NCT06992427
High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer
Alliance for Clinical Trials in Oncology
Pre-treatment window Registry sentence: “No prior treatment for head and neck cancer”
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 3196 sites
RecruitingAustria, Belgium, Bulgaria, Brazil, Canada, China
NCT04892173
JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC
Johnson & Johnson Enterprise Innovation Inc.
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 1/21 site
Not yet recruitingUnited States
NCT07552558
Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)
Washington University School of Medicine
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 1/256 sites
RecruitingChina, Germany, Spain, France, United Kingdom, Japan
NCT06385080
A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer
Janssen Research & Development, LLC
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 125 sites
RecruitingSpain, France, Japan, United States
NCT07219212
A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma
Johnson & Johnson Enterprise Innovation Inc.
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 2232 sites
RecruitingUnited States
NCT05136196
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
National Cancer Institute (NCI)
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.gov
The same sites as a list
- United States222 open trials
- China91 open trials
- Spain41 open trials
- France36 open trials
- Australia33 open trials
- Canada29 open trials
- Japan26 open trials
- Taiwan25 open trials
- Germany25 open trials
- Italy25 open trials
- United Kingdom24 open trials
- South Korea23 open trials
- Belgium19 open trials
- Poland13 open trials
- Israel12 open trials
- Netherlands10 open trials
- Switzerland10 open trials
- India8 open trials
- Brazil8 open trials
- Portugal7 open trials
- Austria6 open trials
- Czechia6 open trials
- Romania6 open trials
- Hungary6 open trials
- Singapore4 open trials
- Puerto Rico4 open trials
- Malaysia4 open trials
- Ireland4 open trials
- Norway4 open trials
- Sweden4 open trials
- Egypt4 open trials
- Mexico3 open trials
- Türkiye3 open trials
- Argentina3 open trials
- Georgia2 open trials
- Pakistan2 open trials
- Serbia2 open trials
- Greece2 open trials
- Bulgaria2 open trials
- Philippines2 open trials
- Thailand2 open trials
- Denmark2 open trials
- Vietnam2 open trials
- Russia1 open trial
- Slovenia1 open trial
- Finland1 open trial
- Croatia1 open trial
- Hong Kong1 open trial
- Chile1 open trial
- Jordan1 open trial
- New Zealand1 open trial
- Uganda1 open trial
- Moldova1 open trial
- United Arab Emirates1 open trial
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
What changed in the last 7 days
Registry facts, one per line, newest first.
New in the registry
MyPatientPal+: A Smartphone App and a Provider Dashboard to Manage Patient Care While on Treatment
NCT07928154 · No phase · United States
Source: ClinicalTrials.govNew in the registry
Lidocaine Infiltration and Neuroimmunomodulation in Head and Neck Cancer Surgery
NCT07922759 · Phase 4 · Slovenia
Source: ClinicalTrials.govOpened for recruitment
NCT07807163 · Phase 2 · Belgium, Germany, Spain, France, Italy, Netherlands
Source: ClinicalTrials.govPhase changed: Phase 1 → Phase 1/2
Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors
NCT07151040 · Phase 1/2 · Spain, France, United Kingdom
Source: ClinicalTrials.govOpened for recruitment
DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors
NCT06953089 · Phase 2 · Australia, China, Germany, Spain, France, Italy
Source: ClinicalTrials.govPhase changed: Phase 1 → Early Phase 1
PET-imaging of Two Vartumabs in Patients With Solid Tumors
NCT06645808 · Early Phase 1 · Netherlands
Source: ClinicalTrials.govOpened for recruitment
PET-imaging of Two Vartumabs in Patients With Solid Tumors
NCT06645808 · Early Phase 1 · Netherlands
Source: ClinicalTrials.gov
Show more
Phase changed: Phase 1 → Early Phase 1
[177Lu]Lu-AKIR001 First-in-human Study
NCT06639191 · Early Phase 1 · Sweden
Source: ClinicalTrials.govOpened for recruitment
NCT06256588 · Phase 3 · United Arab Emirates, Argentina, Australia, Belgium, Brazil, Canada
Source: ClinicalTrials.govClosed for recruitment
NCT06082167 · Phase 2/3 · Argentina, Austria, Australia, Belgium, Bulgaria, Brazil
Source: ClinicalTrials.govClosed for recruitment
A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2
NCT06003231 · Phase 2 · Australia, Canada, Germany, Spain, France, United Kingdom
Source: ClinicalTrials.govPhase changed: Phase 1/2 → Phase 1
A Study to Evaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast Cancer
NCT05683418 · Phase 1 · Spain, United States
Source: ClinicalTrials.govClosed for recruitment
NCT05029882 · Phase 1 · Australia, Germany, Spain, France, Israel, Japan
Source: ClinicalTrials.govOpened for recruitment
Induction and Maintenance Treatment With PARP Inhibitor and Immunotherapy in HPV-negative HNSCC
NCT04681469 · Phase 2 · Italy
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
NCT04590963 · Phase 3 · Argentina, Austria, Australia, Belgium, Bulgaria, Brazil
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors
NCT04083599 · Phase 1/2 · Germany, Denmark, Spain, France, United Kingdom, Georgia
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
NCT04044859 · Phase 1 · Canada, Spain, United States
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and Lymphomas
NCT02503423 · Phase 1/2 · Belgium, Canada, Spain, France, United Kingdom, Hungary
Source: ClinicalTrials.govClosed for recruitment
Induction and Maintenance Treatment With PARP Inhibitor and Immunotherapy in HPV-negative HNSCC
NCT04681469 · Phase 2 · Italy
Source: ClinicalTrials.govOpened for recruitment
NCT06082167 · Phase 2/3 · Argentina, Austria, Australia, Belgium, Bulgaria, Brazil
Source: ClinicalTrials.govClosed for recruitment
NCT06256588 · Phase 3 · United Arab Emirates, Argentina, Australia, Belgium, Brazil, Canada
Source: ClinicalTrials.govStatus changed: Recruiting → Not yet recruiting
NCT07807163 · Phase 2 · Belgium, Germany, Spain, France, Italy, Netherlands
Source: ClinicalTrials.govClosed for recruitment
PET-imaging of Two Vartumabs in Patients With Solid Tumors
NCT06645808 · Early Phase 1 · Netherlands
Source: ClinicalTrials.govOpened for recruitment
A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2
NCT06003231 · Phase 2 · Australia, Canada, Germany, Spain, France, United Kingdom
Source: ClinicalTrials.govOpened for recruitment
NCT05029882 · Phase 1 · Australia, Germany, Spain, France, Israel, Japan
Source: ClinicalTrials.govStatus changed: Recruiting → Not yet recruiting
DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors
NCT06953089 · Phase 2 · Australia, China, Germany, Spain, France, Italy
Source: ClinicalTrials.govStatus changed: Running, not recruiting → Completed
Pembrolizumab, INCB081776, and Radiation Therapy for Head and Neck Squamous Cell Carcinoma
NCT06308913 · Early Phase 1 · United States
Source: ClinicalTrials.govClosed for recruitment
A Study of Evofosfamide in Combination With Zalifrelimab and Balstilimab
NCT06782555 · Phase 1/2 · United States
Source: ClinicalTrials.gov
New reviews, guidelines and randomised trials in PubMed
Systematic review
Head and neck pathology · PubMed
Systematic review
Financial toxicity in patients with head and neck cancer: a scoping review.
BMC cancer · PubMed
Meta-analysis
Current oncology reports · PubMed
Randomised trial
Lasers in medical science · PubMed
Systematic review
Frontiers in endocrinology · PubMed
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
No phaseEnded 1 Nov 2026
No phaseEnded 15 Oct 2026
Completed30 participants
NCT06214611
Prospective Validation of Adaptive Radiotherapy (ART) in Patients With Head and Neck Tumors
No phaseEnded 14 Oct 2026
Phase 1/2Ended 1 Oct 2026
Stopped early194 participants
NCT04868877
Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination
Reason given: The Sponsor terminated the trial early for strategic business reasons. This isn't related to any safety/efficacy/clinical activity/benefit-risk concern with petosemtamab. Ongoing participants will have access to treatment outside of this trial.
No phaseEnded 18 Sept 2026
Early Phase 1Ended 16 Sept 2026
Completed10 participants
NCT06308913
Pembrolizumab, INCB081776, and Radiation Therapy for Head and Neck Squamous Cell Carcinoma
No phaseEnded 1 Sept 2026
No phaseEnded 31 Aug 2026
Phase 2Ended 31 Aug 2026
Completed18 participants
NCT03529422
Durvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN
No phaseEnded Aug 2026
Withdrawn before start0 participants
NCT06362421
Saliva Testing for High-Risk Human Papillomavirus Infection Oral Cavity and Pharynx Cancer
Reason given: PI not moving forward with study at our institution
Phase 3Ended 25 Aug 2026
Stopped early12 participants
NCT06790966
Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Reason given: The study is being discontinued solely based on financial constraints and is not related to the safety of study participants, the investigational product, PDS0101, nor the conduct of the study.
No phaseEnded 24 Aug 2026
Completed12 participants
NCT05538533
Hypofractionated Preoperative Radiation for Head and Neck Cancers (HyPR-HN)
Phase 1/2Ended 21 Aug 2026
Completed55 participants
NCT04708470
A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers
No phaseEnded 12 Aug 2026
Paused74 participants
NCT07268092
Porcine Extracellular Matrix Nerve Wrap in Neck Dissection for Head and Neck Cancer
Reason given: Dr Tam have collected the first 20 patients for interim analysis per the protocol, and are trying to get these data to perform interim analyses on these data to best understand how to move forwards.
Phase 1Ended 10 Aug 2026
Early Phase 1Ended 8 Aug 2026
Phase 2Ended 4 Aug 2026
Completed4 participants
NCT06145412
A Study of Xevinapant With Cisplatin and Radiation Therapy After Surgery in People With Head and Neck Cancer
Phase 2Ended 1 Aug 2026
Withdrawn before start0 participants
NCT05724849
Venlafaxine for the Prevention of Depression in Patients With Head and Neck Cancer
Reason given: Issues with funding
No phaseEnded 1 Aug 2026
Completed900 participants
NCT05565313
Predicting Radiological Extranodal Extension in Oropharyngeal Carcinoma Patients Using AI
Phase 2Ended 1 Aug 2026
Completed10 participants
NCT06508606
AK117 (Anti-CD47 mAb) Plus Cetuximab as Second-Line Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Show more
Phase 1Ended 31 Jul 2026
Phase 1Ended 31 Jul 2026
No phaseEnded 31 Jul 2026
No phaseEnded 29 Jul 2026
Completed42 participants
NCT06627075
Optical Surface Guidance for External Radiotherapy of Head and Neck Cancer
No phaseEnded 24 Jul 2026
Completed49 participants
NCT03972072
MRI - Guided Adaptive RadioTHerapy for Reducing XerostomiA in Head and Neck Cancer (MARTHA-trial)
Phase 2Ended 23 Jul 2026
Completed160 participants
NCT05909904
A Study of Tislelizumab in Combination With Investigational Agents in Participants With Head and Neck Squamous Cell Carcinoma
No phaseEnded 15 Jul 2026
Completed150 participants
NCT03729518
TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck
No phaseEnded 13 Jul 2026
Completed82 participants
NCT05119036
Adjuvant Treatment Deintensification After Transoral Surgery for Human Papillomavirus-Positive Squamous Cell Carcinoma
Phase 1/2Ended 9 Jul 2026
Phase 2Ended 6 Jul 2026
No phaseEnded Jun 2026
Withdrawn before start0 participants
NCT06094621
Effect of Pre-operative Virtual Visits on Patients With Head and Neck Cancer Undergoing Surgery
Reason given: No Investigator Interest
Phase 2Ended Jun 2026
Withdrawn before start0 participants
NCT01451853
SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss
Reason given: Study did not start
No phaseEnded Jun 2026
No phaseEnded Jun 2026
Withdrawn before start0 participants
NCT06603155
Time Restricted Eating (TRE) in Metastatic Head and Neck Squamous Cell Cancer (mHNSCC) or Unresectable or Metastatic Renal Cell Carcinoma (RCC)
Reason given: Changing priorities of portfolio
Phase 2Ended 30 Jun 2026
Withdrawn before start0 participants
NCT06804850
Neoadjuvant Radiotherapy Plus Targeted Therapy and Immunotherapy vs. Targeted Therapy Plus Immunotherapy in Resectable HNSCC
Reason given: The study was withdrawn prior to participant enrollment due to administrative and protocol optimization considerations.
No phaseEnded 26 Jun 2026
Completed25 participants
NCT07682285
Taiwanese Green Propolis for Lipid Profiles, Fatigue, and Quality of Life in Oral Cavity Cancer Survivors
Phase 2Ended 26 Jun 2026
Phase 3Ended 25 Jun 2026
Completed161 participants
NCT07435324
A Comparative Study of Efficacy and Safety of RPH-002 and Erbitux® in Unresectable Metastatic or Recurrent Head and Neck Squamous Cell Carcinoma
Phase 2Ended 23 Jun 2026
Phase 1Ended 22 Jun 2026
No phaseEnded 21 Jun 2026
Completed42 participants
NCT05935995
Intraoperative Assessment of Surgical Margins Using Confocal Microscopy in Comparison With Reference Extemporaneous Examination
Phase 2Ended 18 Jun 2026
Withdrawn before start0 participants
NCT06990737
Phase 2 Pragmatic Trial of Sentinel Lymph Node Biopsy (SLNB) in Patients With Clinically Node-Negative (cN0), High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck
Reason given: Poor accrual
No phaseEnded 8 Jun 2026
Completed16 participants
NCT06441266
M-PART in Head and Neck Cancer Patients Treated With KeraStat Cream for Acute Radiation Dermatitis
Phase 1/2Ended 2 Jun 2026
Completed98 participants
NCT05864144
A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors
No phaseEnded 1 Jun 2026
Withdrawn before start0 participants
NCT07670403
Digital Phenotyping of Psychological Distress in Skin Cancer Patients
Reason given: poor accrual
Phase 2Ended 1 Jun 2026
Withdrawn before start0 participants
NCT05743270
Study of RP3 in Combination With Nivolumab and Other Therapy in Patients With Locoregionally Advanced or Recurrent SCCHN
Reason given: Sponsor decision
Phase 1Ended 1 Jun 2026
Completed90 participants
NCT04670679
A Dose Escalation/Expansion Study of ERAS-601 in Patients With Advanced or Metastatic Solid Tumors
Phase 2Ended 22 May 2026
No phaseEnded 21 May 2026
Phase 1Ended 20 May 2026
Phase 1/2Ended 14 May 2026
Completed51 participants
NCT04287868
Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies
Phase 1Ended 14 May 2026
Completed13 participants
NCT03336606
Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma
Phase 1/2Ended 11 May 2026
Completed43 participants
NCT03650764
Ramucirumab + Pembrolizumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
No phaseEnded 6 May 2026
Completed144 participants
NCT06674499
Development and Evaluation of the Support Intervention for Head and Neck Cancer Patients
Phase 2Ended 4 May 2026
Withdrawn before start0 participants
NCT05363709
BALSTILIMAB on Viral Clearance in HPV+ Oropharyngeal Cancer Patients
Reason given: 0 participants
Phase 1Ended 24 Apr 2026
Completed16 participants
NCT02308072
Phase I Study of Olaparib Combined With Cisplatin-based Chemoradiotherapy to Treat Locally Advanced Head and Neck Cancer
Phase 2Ended 23 Apr 2026
Completed16 participants
NCT03494322
EACH: Evaluating Avelumab in Combination With Cetuximab in Head and Neck Cancer
No phaseEnded 23 Apr 2026
Phase 1Ended 16 Apr 2026
Phase 1Ended 16 Apr 2026
Stopped early68 participants
NCT05983133
A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors
Reason given: The trial was terminated for strategic reasons. The decision was not based on any safety concerns
Not medical advice. fetched 11 Nov 2026