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Diabetic eye disease: trials for referral

171 open trials in the registries we read. Each row links to its registry record.

Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.

Diabetic eye disease·What we know·Glossary

Where the open trials are

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Patient ageOnly trials with a pre-treatment window

171 trials shown

Phase 112 sites
RecruitingUnited States
NCT07425522
A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)
Genentech, Inc.
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 14 sites
RecruitingUnited States
NCT07588100
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7663498 Following Intravitreal Administration in Participants With Diabetic Retinopathy
Hoffmann-La Roche
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 392 sites
RecruitingChina, Japan, Puerto Rico, United States
NCT07867080
A Phase 3 Trial for Intravitreal Injection of 4D-150 in Adults With Diabetic Macular Edema (DME).
4D Molecular Therapeutics
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 21 site
RecruitingEgypt
NCT07917338
Oral N-Acetylcysteine on Diabetic Macular Edema
Khadija Ahmed Mhrose Glal
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 335 sites
RecruitingArgentina, Australia, United Kingdom, United States
NCT07705555
A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)
Merck Sharp & Dohme LLC
Pre-treatment window Registry sentence: “For participants who are treatment-naïve for DME, the diagnosis must have been made within 9 months of screening.”
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 320 sites
RecruitingUnited States
NCT07705607
A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)
Merck Sharp & Dohme LLC
Pre-treatment window Registry sentence: “For participants who are treatment-naïve for DME, the diagnosis must have been made within 9 months of screening.”
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 346 sites
RecruitingArgentina, United States
NCT07734844
A Study to Evaluate the Efficacy and Safety of Tabirafusp Tedromer Compared to Aflibercept in Participants With DME - ALTO
Kodiak Sciences Inc
Pre-treatment window Registry sentence: “DME, treatment-naïve or previously-treated”
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 2/340 sites
RecruitingPuerto Rico, United States
NCT07592273
Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema
AbbVie
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 289 sites
RecruitingGermany, Spain, United Kingdom, Hungary, Italy, Japan
NCT06321302
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy
Boehringer Ingelheim
Registry updated 28 Oct 2026 · The registries disagree on the status
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 31 site
By invitation onlyPakistan
NCT07897630
Suprachoroidal Bevacizumab Versus Intravitreal Bevacizumab in Diabetic Macular Edema
Khyber Teaching Hospital
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 216 sites
RecruitingUnited States
NCT07812090
A Randomized, Phase 2 Study of Oral BGE-102 in Participants With Center-Involved Diabetic Macular Edema
BioAge Labs, Inc.
Pre-treatment window Registry sentence: “Study Eye may be treatment naïve (never received treatment) or previously treated and if previously treated, meets washout requirements”
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 41 site
Not yet recruitingUnited States
NCT07891910
Iopidine to Decrease Intraocular Pressure Rise After Injections
Retina Consultants of Delmarva
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 48 sites
RecruitingUnited States
NCT07567833
Longitudinal Study of Retinal Function in Eyes Treated for Diabetic Macular Edema With Anti-VEGF Agents
Jaeb Center for Health Research
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 20 sites
Not yet recruiting
NCT07459829
Study of CU06-1004 in Patients With Daibetic Macular Edema
Curacle Co., Ltd.
Pre-treatment window Registry sentence: “Has definite retinal thickening due to DME in the center of the macula of the study eye (either treatment-naïve or previously treated patients).”
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 12 sites
RecruitingGreece, United States
NCT05147701
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Exosomes for NAION
The Foundation for Orthopaedics and Regenerative Medicine
Registry updated 16 Oct 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 297 sites
RecruitingChina, Czechia, Germany, United Kingdom, Hungary, Japan
NCT06962839
A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema
Boehringer Ingelheim
Registry updated 16 Oct 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 1/229 sites
RecruitingPuerto Rico, United States
NCT07553429
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
Boehringer Ingelheim
Registry updated 14 Oct 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 20 sites
Not yet recruiting
NCT07870226
Suprachoroidal Triamcinolone Acetonide Monotherapy in Treatment-naive Center Involving Diabetic Macular Edema
Khyber Girls Medical College
Pre-treatment window Registry sentence: “The study eye must be treatment-naive, with no prior anti-VEGF therapy, intravitreal or periocular steroid, or focal/grid laser for DME.”
Registry updated 13 Oct 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 41 site
Not yet recruitingUnited States
NCT07864480
Continuous Delivery of Ranibizumab Via the Port Delivery System for Proliferative Diabetic Retinopathy-related Vitreous Hemorrhage With Pars Plana Vitrectomy and Limited PRP.
Southeast Retina Center, Georgia
Registry updated 13 Oct 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 21 site
RecruitingUnited States
NCT07383701
Lactiplantibacillus Plantarum 299v Probiotic Supplementation in Patients With Diabetic Macular Edema
Massachusetts Eye and Ear Infirmary
Registry updated 30 Sept 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 41 site
RecruitingUnited States
NCT07843849
Corticosteroid for Diabetic Macular Edema (DME) Study
Vanderbilt University Medical Center
Registry updated 28 Sept 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 322 sites
RecruitingUnited Kingdom
NCT06985706
Anti-vascular Endothelial Growth Factor (Anti-VEGF) Monotherapy vs Anti-VEGF Followed by Subthreshold Micropulse Laser for Treating Severe Diabetic Macular Oedema When the Central Retina Goes <400 Microns
Belfast Health and Social Care Trust
Registry updated 28 Sept 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 30 sites
Not yet recruiting
NCT07841899
Phase 3 Study of Intravitreal OLN324 in Adults With Diabetic Macular Edema (DME) (OLN324-CP-02)
Ollin Biosciences, Inc.
Pre-treatment window Registry sentence: “Participants may be either treatment-naïve or previously-treated for DME in their study eye.”
Registry updated 25 Sept 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 30 sites
Not yet recruiting
NCT07842016
Phase 3 Study of Intravitreal OLN324 in Adults With Diabetic Macular Edema (DME) (OLN324-CP-03)
Ollin Biosciences, Inc.
Pre-treatment window Registry sentence: “Participants may be either treatment-naïve or previously-treated for DME in their study eye.”
Registry updated 25 Sept 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 110 sites
RecruitingAustralia, Georgia
NCT06701721
A Study Intravitreal THN391 in Diabetic Macular Oedema Secondary to Non-Proliferative Diabetic Retinopathy.
Therini Bio Pty Ltd
Registry updated 21 Sept 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 334 sites
RecruitingUnited States
NCT06790784
Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR
Jaeb Center for Health Research
Registry updated 18 Sept 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 10 sites
Not yet recruiting
NCT07817121
A First-in-human Trial of SZN-8141 in Diabetic Macular Edema
Surrozen Operating, Inc.
Pre-treatment window Registry sentence: “Treatment naïve and previously treated participants with protocol specified drug washout”
Registry updated 14 Sept 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 11 site
Not yet recruitingChina
NCT07817615
A Phase I Study of GenSci148 Intravitreal Injection for Neovascular Age-related Macular Degeneration, Diabetic Macular Edema and Retinal Vein Occlusion
Changchun GeneScience Pharmaceutical Co., Ltd.
Registry updated 14 Sept 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 40 sites
Not yet recruiting
NCT07753616
South Asian Patients With Diabetic Macular Oedema Treated With Faricimab Assessing the Efficacy, Durability, and Safety (SEAFAR Study)
Birmingham and Midland Eye Centre Sandwell and west Birmingham NHS trust
Pre-treatment window Registry sentence: “Centre-involving diabetic macular oedema (DMO) confirmed on SD-OCT, with a central subfield thickness (CST) ≥400 µm, in line with UK NICE guidance in the treatment naïve patients (75% of the cohort). 25% of cohort is previously treated DMO where treatment commenced within 3 years of the screening visit and responded to the anti VEGF, reviewed during this period and developed any clinically significant recurrence of DMO, with vision at least 6/18 or better in the enrolled eye.”
Registry updated 7 Aug 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site
Phase 15 sites
RecruitingUnited States
NCT05802329
Phase I Study to Assess the Safety and Efficacy of OCU200 for Center-Involved Diabetic Macular Edema (DME)
Ocugen
Registry updated 31 Jul 2026
Registry record: ClinicalTrials.gov
Compare criteriaReferral pack Letter to the site

160 sites Pre-treatment window

The same sites as a list

Who treats this

Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.

Aier Eye Hospital Group (China)
Changsha Shi, China
1 trial · 20 publications · ROR
Ain Shams University
Cairo, Egypt
2 trials · 12 publications · ROR
All India Institute of Medical Sciences
New Delhi, India
1 trial · 36 publications · ROR
Aravind Eye Hospital
Madurai, India
1 trial · 19 publications · ROR
Asan Medical Center
Seoul, South Korea
4 trials · 13 publications · ROR
Beijing Tongren Hospital
Beijing, China
3 trials · 32 publications · ROR
Cleveland Clinic
Cleveland, United States
4 trials · 36 publications · ROR
Doheny Eye Institute
Los Angeles, United States
1 trial · 23 publications · ROR
Duke Medical Center
Durham, United States
1 trial · 14 publications · ROR
Duke University
Durham, United States
1 trial · 27 publications · ROR
Eye & ENT Hospital of Fudan University
Shanghai, China
4 trials · 27 publications · ROR
First Affiliated Hospital of Harbin Medical University
Harbin, China
1 trial · 21 publications · ROR
First Affiliated Hospital of Jinan University
Guangzhou, China
1 trial · 13 publications · ROR
First Affiliated Hospital of Zhengzhou University
Zhengzhou, China
1 trial · 13 publications · ROR
Fondazione G.B. Bietti
Rome, Italy
1 trial · 13 publications · ROR
Guangdong Provincial People's Hospital
Guangzhou, China
1 trial · 24 publications · ROR
IRCCS Ospedale San Raffaele
Milan, Italy
2 trials · 18 publications · ROR
Joint Shantou International Eye Center
Shantou, China
1 trial · 16 publications · ROR
Joslin Diabetes Center
Boston, United States
5 trials · 13 publications · ROR
L V Prasad Eye Institute
Hyderabad, India
2 trials · 21 publications · ROR
Linkou Chang Gung Memorial Hospital
Taoyuan, Taiwan
3 trials · 14 publications · ROR
Massachusetts Eye and Ear Infirmary
Boston, United States
1 trial · 49 publications · ROR
Mayo Clinic
Rochester, United States
4 trials · 17 publications · ROR
Medical University of Vienna
Vienna, Austria
4 trials · 16 publications · ROR
Moorfields Eye Hospital
London, United Kingdom
7 trials · 28 publications · ROR
Moorfields Eye Hospital NHS Foundation Trust
London, United Kingdom
2 trials · 37 publications · ROR
Narayana Nethralaya
Bengaluru, India
2 trials · 13 publications · ROR
Northwestern University
Evanston, United States
1 trial · 31 publications · ROR
Oregon Health & Science University
Portland, United States
3 trials · 13 publications · ROR
Peking Union Medical College Hospital
Beijing, China
3 trials · 14 publications · ROR

What changed in the last 7 days

RSS feed (30 days)Calendar reminder

Registry facts, one per line, newest first.

9 Nov 2026
New in the registry
Macular Vascular Density After Aflibercept or Ranibizumab Treatment for Diabetic Macular Edema
NCT07924072 · Phase 4 · Egypt
Source: ClinicalTrials.gov
6 Nov 2026
New in the registry
To Investigate the Feasibility and Acceptability of Trained Non-medical Professionals Performing Laser Treatment for Proliferative Diabetic Retinopathy (PDR), and the Potential Impact on Service Capacity. Assess Feasibility of Conducting a Full Trial Comparing Trained ECPs With Ophthalmologists
NCT07923292 · No phase · United Kingdom
Source: ClinicalTrials.gov
6 Nov 2026
Closed for recruitment
Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With and Without Diabetic Retinopathy
NCT05296447 · Phase 2 · United States
Source: ClinicalTrials.gov
6 Nov 2026
Closed for recruitment
Pivotal Trial of Automated Artificial Intelligence (AI) Based System for Early Diagnosis of Diabetic Retinopathy
NCT07151001 · No phase · United States
Source: ClinicalTrials.gov
5 Nov 2026
Closed for recruitment
Video-based Patient Education Intervention for Diabetic Eye Screening in Latinx Communities
NCT06257082 · No phase · United States
Source: ClinicalTrials.gov
2 Dec 2025
Opened for recruitment
Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Diabetic Retinopathy or Retinal Vein Occlusion
NCT07259928 · Phase 2 · Germany, United Kingdom
Source: ClinicalTrials.gov
28 Oct 2026
Opened for recruitment
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy
NCT06321302 · Phase 2 · Germany, Spain, United Kingdom, Hungary, Italy, Japan
Source: ClinicalTrials.gov
14 Jul 2026
Closed for recruitment
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy
NCT06321302 · Phase 2 · Germany, Spain, United Kingdom, Hungary, Italy, Japan
Source: ClinicalTrials.gov
28 Jul 2026
Closed for recruitment
Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Diabetic Retinopathy or Retinal Vein Occlusion
NCT07259928 · Phase 2 · Germany, United Kingdom
Source: ClinicalTrials.gov
4 Nov 2026
New in the registry
Oral N-Acetylcysteine on Diabetic Macular Edema
NCT07917338 · Phase 2 · Egypt
Source: ClinicalTrials.gov
4 Nov 2026
Status changed: Running, not recruiting → Completed
Effect of AIV007 by Periocular Administration in Subjects With Macular Edema Secondary to nAMD and DME
NCT05698329 · Phase 1 · United States
Source: ClinicalTrials.gov

Results card

Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.

No phaseEnded 13 Oct 2026
Completed1811 participants
NCT06257082
Video-based Patient Education Intervention for Diabetic Eye Screening in Latinx Communities
Registry record
Phase 1Ended 8 Oct 2026
Withdrawn before start0 participants
NCT06881888
Intranasal Delivery of Octreotide for Treatment of Diabetic Macular Edema
Reason given: Project terminated due to loss of sponsor funding following the dissolution of AMD Opti.
Registry record
Phase 2Ended 1 Oct 2026
Completed9 participants
NCT07354477
Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation
Registry record
Phase 4Ended 30 Sept 2026
Completed100 participants
NCT07868458
Randomized, Controlled Study to Investigate the 12-month Efficacy and Safety of Resveratrol Vitamin Supplements in Patients With Non-proliferative Diabetic Retinopathy Without Center Involved Diabetic Macular Edema (REVOLUTION Study)
Registry record
Phase 2Ended 22 Sept 2026
Completed33 participants
NCT07844343
A Trial to Evaluate the Safety and Usability of the SB15 PFS in Trial Participants With AMD, Macular Oedema Secondary to RVO, or Diabetic Macular Oedema
Registry record
Phase 2Ended 3 Sept 2026
Completed53 participants
NCT04116398
Pilot and Phase 2 Study of the Efficacy of a Treatment Protocol With Dexamethasone Implant Loading Dose in Patients With Diabetic Macular Edema (LOADEX)
Registry record
Phase 2Ended 20 Aug 2026
Completed60 participants
NCT06708260
A Phase 2 Study to Evaluate the Efficacy and Safety of ENN0403 in Subjects With DME
Registry record
No phaseEnded 13 Aug 2026
Completed236 participants
NCT05978622
Observational Study of Adult Participants With Diabetic Macular Edema and Suboptimal Response to Anti-Vascular Endothelial Growth Factor Treated With Dexamethasone Intravitreal Implant
Registry record
Phase 4Ended 11 Aug 2026
Completed50 participants
NCT07779356
Patient Comfort Following Intravitreal Injections Using Iheezo Versus Standard Anesthesia
Registry record
Phase 1/2Ended 11 Aug 2026
Completed38 participants
NCT06664502
A 2-part Study Consisting of a Multiple Ascending Dose Safety Study in Participants With Macular Edema Following Branch Retinal Vein Occlusion and a Dose-finding Safety and Preliminary Efficacy Study in Participants With Either Diabetic Macular Edema or Neovascular Age-related Macular Degeneration
Registry record
Early Phase 1Ended 19 Jul 2026
Completed60 participants
NCT06879301
Effectiveness of Intravitreal Injection of Aflibercept 8 mg in Resistant Diabetic Macular Edema, Retinal Vein Occlusion and Myopic Choroidal Neovascularisation Patients
Registry record
Phase 2Ended 14 Jul 2026
Completed56 participants
NCT06845163
Randomized Clinical Trial to Evaluate the Effect of Dapagliflozin in Patients With Diabetic Macular Edema
Registry record
No phaseEnded 1 Jul 2026
Stopped early24 participants
NCT04699864
Evaluation of NeoRetina Artificial Intelligence Algorithm for the Screening of Diabetic Retinopathy at the CHUM
Reason given: logistical constraints
Registry record
No phaseEnded 30 Jun 2026
Completed935 participants
NCT07151001
Pivotal Trial of Automated Artificial Intelligence (AI) Based System for Early Diagnosis of Diabetic Retinopathy
Registry record
No phaseEnded 30 Jun 2026
Completed68 participants
NCT07850245
The Effect of Different Auditory Types on Visual Evoked Potentials (VEP)
Registry record
Phase 1/2Ended 19 Jun 2026
Completed388 participants
NCT06850922
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7446603 Administered Alone or in Combination With Aflibercept or Faricimab in Participants With Diabetic Macular Edema
Registry record
No phaseEnded 17 Jun 2026
Completed198 participants
NCT07404657
Preliminary Assessment of an Automated Tool for Diabetic Retinopathy Screening
Registry record
Phase 2Ended 1 Jun 2026
Completed33 participants
NCT07501052
Study of the SCD411 Prefilled Syringe for Treating Adults With Wet Age-Related Macular Degeneration, Retinal Vein Occlusion, Diabetic Macular Edema, or Diabetic Retinopathy
Registry record
No phaseEnded 22 May 2026
Completed10 participants
NCT07318428
AI-Assisted Detection of Posterior Segment Diseases: DR, AMD, RVO, and Glaucoma
Registry record
Phase 3Ended 17 May 2026
Completed70 participants
NCT06305416
A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema
Registry record

Show more

Phase 1Ended 21 Apr 2026
Completed164 participants
NCT04505566
INflammatory MediatorS in the PathophysIology of Diabetic REtinopathy Study
- INFLAMMATORY MEDIATORS IN DIABETIC MACULAR EDEMA: A Prospective, Controlled Study. · Retina (Philadelphia, Pa.), 2026
Registry record
Phase 1Ended 17 Apr 2026
Stopped early3 participants
NCT07228559
A Study of Avoralstat In Participants With Diabetic Macular Edema
Reason given: Strategic decision
Registry record
No phaseEnded 15 Apr 2026
Completed60 participants
NCT07663370
Effectiveness of Biosimilar Ranibizumab in the Management of Diabetic Macular Edema
Registry record
Phase 2/3Ended 10 Apr 2026
Completed552 participants
NCT05066997
A Pivotal Safety and Efficacy Study of OCS-01 Eye Drops in Participants With Diabetic Macular Edema (DIAMOND 1)
- Safety and efficacy of topical OCS-01 ophthalmic suspension for the treatment of diabetic macular oedema: stage 1 of a multicentre, double-blind, randomised, vehicle-controlled phase 2/3 trial. · EClinicalMedicine, 2026
Registry record
Phase 3Ended 2 Apr 2026
Completed401 participants
NCT06172257
A Pivotal Safety and Efficacy Study of OCS-01 Eye Drops in Participants With Diabetic Macular Edema (DIAMOND 2)
Registry record
Phase 4Ended 1 Apr 2026
Completed30 participants
NCT07690800
Outcomes of Intravitreal Ranibizumab Injection for Diabetic Vitreous Hemorrhage
Registry record
Phase 3Ended 25 Mar 2026
Completed333 participants
NCT06422507
A Study to Learn More About How Well 8 Milligram Aflibercept Works and How Safe it is in Chinese Participants With Diabetic Macular Edema
Registry record
Phase 2Ended 26 Feb 2026
Completed179 participants
NCT05681884
Safety and Efficacy of Faricimab in Patients With NPDR
- MAGIC: Study Design and Rationale for the Phase 2 Clinical Trial of Faricimab for Non-Proliferative Diabetic Retinopathy. · Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2026
Registry record
Phase 1Ended 25 Feb 2026
Stopped early1 participant
NCT06781255
Evaluation of K9 in Subjects With Diabetic Macular Edema (DME)
Reason given: Low recruitment outcome
Registry record
Phase 3Ended 23 Feb 2026
Completed174 participants
NCT04503551
A Multicenter, Randomized Study in Participants With Diabetic Retinopathy Without Center-involved Diabetic Macular Edema To Evaluate the Efficacy, Safety, and Pharmacokinetics of Ranibizumab Delivered Via the Port Delivery System Relative to the Comparator Arm
Registry record
No phaseEnded 18 Feb 2026
Completed90 participants
NCT07434362
Serum Endocan, Alarin, and Galanin-Like Peptide Levels in Diabetic Retinopathy
Registry record
Phase 3Ended 13 Feb 2026
Completed255 participants
NCT06270836
A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Diabetic Retinopathy (DR)
Registry record
No phaseEnded 1 Feb 2026
Completed70 participants
NCT07255326
Effect of Omega-3 Fatty Acids on Eye Blood Vessels in Type 1 Diabetes
Registry record
No phaseEnded 13 Jan 2026
Completed136 participants
NCT07544381
Nursing Intervention Based on Stress Adaptation Theory for Patients Undergoing Diabetic Retinal Laser Surgery
Registry record
No phaseEnded 1 Jan 2026
Completed60 participants
NCT07526857
Epivascular Glia Regression and Macular Pigment Restoration After Faricimab in Diabetic Retinopathy
Registry record
No phaseEnded 31 Dec 2025
Completed20 participants
NCT07255885
CRYSTALSIGHT: ''Cohort 1.5" Clinical Investigation Study With OCCUTRACK and Tan Tock Seng Eye Clinic to Further Develop Remote Monitoring of Maculopathy at Home Using Artificial Intelligence for Eye Tracking
Registry record
No phaseEnded 18 Dec 2025
Completed3183 participants
NCT04624737
Intelligent Evaluation of Diabetic Retinopathy
Registry record
Phase 2Ended 10 Dec 2025
Completed27 participants
NCT06003751
A Study of PER-001 in Participants With Diabetic Retinopathy
Registry record
Phase 1Ended 9 Dec 2025
Completed164 participants
NCT07484074
A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Intravitreal OLN324
Registry record
No phaseEnded 28 Nov 2025
Completed736 participants
NCT06723288
A Study Conducted to Evaluate the Conjunctiva and Tenon's Capsule Status of Healthy Subjects and in Participants With Neovascular Age-related Macular Degeneration (nAMD)/Diabetic Macular Edema (DME)
Registry record
Phase 3Ended 25 Nov 2025
Completed509 participants
NCT05217680
Clinical Study to Evaluate PRO-169 for Diabetic Macular Edema
Registry record
No phaseEnded 17 Nov 2025
Completed572 participants
NCT04543331
Observational Study to Evaluate Fluid Resolution and Effectiveness in Patients Receiving Beovu in Neovascular Age-related Macular Degeneration and Visual Impairment Due to Diabetic Macular Edema
Registry record
Phase 2Ended 17 Nov 2025
Completed230 participants
NCT07444892
Levodopa for Diabetic Retinopathy
Registry record
Phase 4Ended 17 Nov 2025
Completed66 participants
NCT05959304
Post Marketing Study to Evaluate the Safety and Effectiveness of Brolucizumab in Patients With Diabetic Macular Edema.
Registry record
No phaseEnded 31 Oct 2025
Completed338 participants
NCT07816627
Applied Conversion Equation for Optical Coherence Tomography
Registry record
No phaseEnded 30 Oct 2025
Completed300 participants
NCT06343350
OPTDR01 Feasibility for Automated Diabetic Retinopathy Detection
Registry record
Phase 1Ended 27 Oct 2025
Completed56 participants
2024-515078-28-00
A phase 1, open-label trial in healthy subjects and in subjects with diabetes investigating pharmacokinetics, tolerability, safety, and food effect following single and multiple dosing of danegaptide
Registry record
Phase 4Ended 14 Oct 2025
Completed51 participants
NCT06591598
A Study to Learn About the Blood Levels of Aflibercept When High-dose Aflibercept is Injected in Both Eyes of Participants With Diabetic Macular Edema or Neovascular Age-related Macular Degeneration
Registry record
Phase 2Ended 30 Sept 2025
Completed19 participants
NCT06599684
Study of INV-102 Ophthalmic Solution in Adults With Diabetic Macular Edema Associated With Non-proliferative Diabetic Retinopathy
Registry record
No phaseEnded 15 Sept 2025
Completed290000 participants
NCT07105228
Incidence of Retinal Vasculitis Among Patients Receiving Aflibercept: A US Real-World Evidence Study
Registry record
No phaseEnded 1 Sept 2025
Completed200 participants
NCT06457295
Impact of Diabetes Mellitus on Retinal Microvasculature in Patients Without Clinical Retinopathy Using Optical Coherence Tomography Angiography
Registry record
No phaseEnded 1 Sept 2025
Completed550000 participants
NCT06769412
A Real-World Evidence Study for the Incidence of Retinal Vasculitis (RV) Among Adult Patients Receiving Aflibercept 2 mg in the United States (US)
Registry record
No phaseEnded 31 Jul 2025
Completed80 participants
NCT07819253
Laser Photocoagulation and Ranibizumab Treatment in Proliferative Diabetic Retinopathy
Registry record
Phase 1Ended 28 Jul 2025
Completed3 participants
NCT06237777
A Clinical Study Evaluating the Safety, Tolerability and Initial Efficacy of SKG0106 Intravitreal Injection in Diabetic Macular Edema (DME) Patients
Registry record
No phaseEnded 30 Jun 2025
Completed1284 participants
NCT07707856
AI Prediction of Treatment Response in DME
Registry record
No phaseEnded 23 Jun 2025
Completed100 participants
NCT07137013
Periodontitis Severity in Patients With Diabetic Retinopathy
Registry record
Phase 1Ended 28 May 2025
Completed3 participants
2023-503683-16-00
A study to investigate the safety, tolerability, pharmacokinetics, and early signs of biological activity of danegaptide following oral administration in participants with diabetic macular edema
Registry record
No phaseEnded 22 May 2025
Completed202 participants
NCT04636307
Characterization of Retinal Disease Progression in Eyes With Non Proliferative Diabetic Retinopathy in Diabetes Type 2 Using Non-invasive Procedures (CHART)
- One-Year Progression of Capillary Nonperfusion in Nonproliferative Diabetic Retinopathy Using Noninvasive Imaging: The CHART Study. · Translational vision science & technology, 2026
Registry record
Phase 4Ended 14 May 2025
Completed23 participants
NCT04411693
Comparative Study of Dexamethasone Implant to Intravitreal Aflibercept in Subjects With Diabetic Macular Edema
Registry record
No phaseEnded 30 Apr 2025
Completed60 participants
NCT05112445
Retinal Ischemia Characterization in Diabetes - "RICHARD"
Registry record

Not medical advice. fetched 10 Nov 2026

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Under construction, not live – Diabetic eye disease: trials for referral – Frontlight Research