Migraine: trials for referral
297 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Where the open trials are
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297 trials shown
No phase1 site
Not yet recruitingChina
NCT07918053
A Prospective Study of Rimegepant for Short-term Preventive Treatment of Night-shift-related Migraine in Healthcare Professionals
Chinese PLA General Hospital
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT07437313
Marine Lipids Ease Painful TMD
University of North Carolina, Chapel Hill
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT07513662
Headache Education and Awareness vs. Daily Mindfulness Strategies - Understanding Pain
University of Colorado, Denver
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
By invitation onlyUnited States
NCT07297901
App-based Breathing Program for Migraine Relief
Arizona State University
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 245 sites
RecruitingAustralia, Canada, New Zealand, United States
NCT07616128
Study of EVO756 in Adults With Migraine
Evommune, Inc.
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 40 sites
Not yet recruiting
NCT07916571
Migraine Menopause Study
Alberta Neurologic Centre
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 372 sites
RecruitingUnited States
NCT07816367
A Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
TriGemX Bio, Inc.
Pre-treatment window Registry sentence: “Has greater than a one-year history of migraine with or without aura as defined by International Headache Society criteria 1.1 and 1.2 and his/her migraines typically last between 4 to 72 hours, if untreated as documented in the patient's medical records from his/her treating physician or with pharmacy records confirming use of a migraine-specific medication (e.g. triptan, gepant, ditan) for \> 1 year, and confirmed by the investigator. 3.”
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 3112 sites
RecruitingUnited States
NCT07645924
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
TriGemX Bio, Inc.
Pre-treatment window Registry sentence: “Has greater than a one-year history of migraine with or without aura as defined by International Headache Society criteria 1.1 and 1.2 and his/her migraines typically last between 4 to 72 hours, if untreated. 3.”
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 3112 sites
RecruitingUnited States
NCT07674654
A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine
TriGemX Bio, Inc.
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT07360405
Dietary Intervention for Migraine Relief
American University
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govPhase 31 site
RecruitingCanada
NCT07191145
Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (ELITE-ACT)
Sunnybrook Health Sciences Centre
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT05046613
Observational Study to Assess Maternal, Fetal and Infant Outcomes Following Exposure to Rimegepant
Pfizer
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
By invitation onlyItaly
NCT06891053
Studio TIARA: Alessitimia ed Emicrania Cronica
Azienda Sanitaria Locale di Alessandria
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 11 site
RecruitingUnited States
NCT07667621
A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acute Treatment of Migraine in the Emergency Department
University of South Florida
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govPhase 3121 sites
RecruitingSpain, Poland, United States
NCT04743141
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
Pfizer
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
Recruiting
NCT07328685
Basic Body Awareness Therapy in Individuals With Migraine
Mustafa Kemal University
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govPhase 3236 sites
RecruitingCanada, China, Spain, United Kingdom, Japan, Mexico
NCT04649242
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Pfizer
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingTaiwan
NCT07891585
Laser Acupuncture for Chronic Migraine: Clinical Response, Traditional Chinese Medicine Syndrome Patterns, and Brain Function
Taichung Veterans General Hospital
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.govPhase 2/383 sites
RecruitingChina
NCT07792681
Efficacy and Safety of BR005-036C Tablets for the Acute Treatment of Migraine in Adults
Brise Pharmaceuticals Co., Ltd.
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.govNo phase3 sites
Not yet recruitingUnited States
NCT07532109
Validation of the Vestibular Migraine Patient Assessment Tool and Handicap Inventory (VM-PATHI) for Adolescents
Boston Children's Hospital
Registry updated 22 Oct 2026
Registry record: ClinicalTrials.govEarly Phase 11 site
RecruitingUnited States
NCT07374640
Virtual Reality and Biofeedback for Adolescents With Chronic Dizziness
Boston Children's Hospital
Registry updated 22 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingItaly
NCT07163416
(Italian Migraine Registry, I-GRAINE-NEW)
IRCCS San Raffaele Roma
Registry updated 20 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT05752396
Overlapping Pain Trajectory Study
Children's Hospital Medical Center, Cincinnati
Registry updated 20 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
By invitation onlyUnited States
NCT06212661
Migraine Medication Effects on Urinary Symptoms
The Cleveland Clinic
Registry updated 19 Oct 2026
Registry record: ClinicalTrials.govPhase 437 sites
RecruitingUnited States
NCT06972056
Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study
Mayo Clinic
Registry updated 19 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingFrance
NCT07877493
Psychological Support for Chronic Migraine Patients Treated With Anti-CGRP (Anti-Calcitonin Gene-Related Peptide ) Monoclonal Antibodies
Central Hospital, Nancy, France
Registry updated 16 Oct 2026
Registry record: ClinicalTrials.govPhase 382 sites
RecruitingArgentina, Canada, Spain, United Kingdom, Italy, Mexico
NCT04965675
A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine
H. Lundbeck A/S
Registry updated 16 Oct 2026 · The registries disagree on the status
Registry record: ClinicalTrials.govNo phase2 sites
RecruitingSpain
NCT05780450
Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.
Fundación Universidad Católica de Valencia San Vicente Mártir
Registry updated 15 Oct 2026
Registry record: ClinicalTrials.govPhase 47 sites
RecruitingIndia
NCT07685769
A Study to Find Out if the Medicine Called Rimegepant is Safe for Adults in India
Pfizer
Pre-treatment window Registry sentence: “Headache attacks lasting 4-72 hours (when untreated or unsuccessfully treated).”
Registry updated 15 Oct 2026
Registry record: ClinicalTrials.govPhase 3106 sites
RecruitingCanada, Spain, France, Italy, Japan, Poland
NCT05156398
Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects
Pfizer
Pre-treatment window Registry sentence: “Migraine attacks, on average, lasting 4 - 72 hours if untreated”
Registry updated 14 Oct 2026
Registry record: ClinicalTrials.gov
The same sites as a list
- United States92 open trials
- China31 open trials
- Italy30 open trials
- Canada19 open trials
- Spain19 open trials
- Denmark15 open trials
- France14 open trials
- Poland11 open trials
- United Kingdom9 open trials
- Egypt9 open trials
- Norway9 open trials
- Japan7 open trials
- Netherlands7 open trials
- Portugal6 open trials
- Argentina6 open trials
- Switzerland6 open trials
- Mexico5 open trials
- Taiwan5 open trials
- Israel5 open trials
- Puerto Rico5 open trials
- Belgium5 open trials
- Austria4 open trials
- Serbia3 open trials
- India3 open trials
- Hungary3 open trials
- Greece3 open trials
- Thailand3 open trials
- Sweden3 open trials
- Pakistan3 open trials
- Germany3 open trials
- Brazil3 open trials
- Australia2 open trials
- Romania2 open trials
- South Korea2 open trials
- Colombia2 open trials
- New Zealand1 open trials
- Finland1 open trials
- Oman1 open trials
- Kyrgyzstan1 open trials
- Hong Kong SAR China1 open trials
- Tunisia1 open trials
- Bangladesh1 open trials
- Czechia1 open trials
- Lebanon1 open trials
- Croatia1 open trials
- Malaysia1 open trials
- Chile1 open trials
- Iran1 open trials
- Slovenia1 open trials
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
Berlin, Germany
0 trials · 31 publications · ROR
Cincinnati Children's Hospital Medical Center
Cincinnati, United States
11 trials · 44 publications · ROR
Fondazione Istituto Neurologico Nazionale Casimiro Mondino
Pavia, Italy
13 trials · 58 publications · ROR
Instituto de Investigación Sanitaria del Hospital Universitario de La Princesa
Madrid, Spain
0 trials · 25 publications · ROR
King Abdullah University of Science and Technology
Jeddah, Saudi Arabia
0 trials · 29 publications · ROR
MedStar Georgetown University Hospital
Washington D.C., United States
0 trials · 43 publications · ROR
National Hospital for Neurology and Neurosurgery
London, United Kingdom
0 trials · 29 publications · ROR
National Institute for Health and Care Research
London, United Kingdom
0 trials · 27 publications · ROR
New England Institute for Neurology and Headache
Stamford, United States
2 trials · 37 publications · ROR
South London and Maudsley NHS Foundation Trust
London, United Kingdom
0 trials · 36 publications · ROR
The Affiliated Yongchuan Hospital of Chongqing Medical University
Chongqing, China
0 trials · 32 publications · ROR
University of Massachusetts Chan Medical School
Worcester, United States
0 trials · 25 publications · ROR
University of North Carolina at Chapel Hill
Chapel Hill, United States
3 trials · 44 publications · ROR
What changed in the last 7 days
Registry facts, one per line, newest first.
Closed for recruitment
App-Based Migraine Treatment: The Health enSuite Study
NCT06797076 · No phase · Canada
Source: ClinicalTrials.govOpened for recruitment
Marine Lipids Ease Painful TMD
NCT07437313 · No phase · United States
Source: ClinicalTrials.govNew in the registry
Clinical and Neurophysiological Effects of tDCS to Visual and Motor Cortex in Migraine
NCT06468189 · No phase
Source: ClinicalTrials.govOpened for recruitment
Headache Education and Awareness vs. Daily Mindfulness Strategies - Understanding Pain
NCT07513662 · No phase · United States
Source: ClinicalTrials.govPhase changed: Phase 3 → Phase 2
Cabergoline for Episodic Migraine
NCT07072910 · Phase 2 · Denmark
Source: ClinicalTrials.govOpened for recruitment
NCT06641466 · Phase 3 · Argentina, Canada, China, Germany, Denmark, Spain
Source: ClinicalTrials.govStatus changed: Recruiting → Not yet recruiting
Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary Care
NCT06499116 · Phase 4 · Spain
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
NCT06047444 · Phase 3 · Canada, Czechia, Germany, Spain, United Kingdom, Georgia
Source: ClinicalTrials.govStatus changed: Recruiting → By invitation only
NCT05707949 · Phase 3 · Belgium, Canada, Denmark, Spain, France, United Kingdom
Source: ClinicalTrials.govOpened for recruitment
A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine
NCT04965675 · Phase 3 · Argentina, Canada, Spain, United Kingdom, Italy, Mexico
Source: ClinicalTrials.govClosed for recruitment
A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine
NCT04965675 · Phase 3 · Argentina, Canada, Spain, United Kingdom, Italy, Mexico
Source: ClinicalTrials.govOpened for recruitment
Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary Care
NCT06499116 · Phase 4 · Spain
Source: ClinicalTrials.govClosed for recruitment
NCT06641466 · Phase 3 · Argentina, Canada, China, Germany, Denmark, Spain
Source: ClinicalTrials.gov
New reviews, guidelines and randomised trials in PubMed
Meta-analysis
Effects of Probiotics on Migraine in Children and Adults: A Systematic Review and Meta-Analysis.
Current pain and headache reports · PubMed
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
No phaseEnded 26 Oct 2026
Completed145 participants
NCT05576467
Treatment for Migraine and Mood
- Evaluating an Abbreviated Version of Mindfulness-Based Cognitive Therapy Delivered via Telephone or Videoconferencing Compared to Enhanced Usual Care-Treatment for Migraine and Mood (TEAM-M) Study: Protocol for a Three-Arm Multisite Randomized Controlled Feasibility Trial. · JMIR research protocols, 2026
No phaseEnded 17 Sept 2026
No phaseEnded 15 Sept 2026
Phase 4Ended 2 Sept 2026
Completed164 participants
NCT06701526
A Trial of Eptinezumab in Participants With Migraine and Insufficient Response to Anti-CGRP Medications
Phase 1Ended 1 Sept 2026
Completed36 participants
2025-525125-12-00
A Study to Compare the Blood Levels of Two Dosage Formulations of the Study Medicine in Healthy Adults
Phase 1Ended 1 Sept 2026
Completed36 participants
NCT07594769
A Study to Compare the Blood Levels of Two Dosage Formulations of the Study Medicine in Healthy Adults
No phaseEnded 31 Aug 2026
Phase 3Ended 11 Aug 2026
Completed2158 participants
NCT06241313
Study of Oral Atogepant Tablets to Assess Safety and Efficacy in Adult Participants With Migraine
- Atogepant for migraine in real-world clinical practice: Insights from a large multicentre study in a treatment-resistant population (GEMA project). · Cephalalgia : an international journal of headache, 2026
- The pharmacology of gepants in migraine: A scoping review on mechanisms, clinical applications, and combination strategies. · Headache, 2026
Phase 2Ended 2 Aug 2026
Completed70 participants
2022-501133-23-00
Migraine and High Flow Oxygenotherapy at the Emergency Department (MiOx)
No phaseEnded 1 Aug 2026
No phaseEnded 20 Jul 2026
Completed45 participants
NCT07802912
Efficacy of Traditional Integrated Islamic Psychotherapy and Cognitive Behavioural Therapy for Migraine: A Randomized Controlled Trial
Phase 4Ended 13 Jul 2026
Completed15 participants
NCT06173661
Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45
No phaseEnded 1 Jul 2026
Completed20 participants
NCT07425041
Effectiveness of Manual Lymphatic Drainage in the Physiotherapeutic Treatment of Migraine
No phaseEnded 30 Jun 2026
Completed220 participants
NCT05690737
Tai Chi for the Prophylaxis of Episodic Migraine: the Efficacy Examination and Mechanism Exploration
No phaseEnded 30 Jun 2026
Completed102 participants
NCT07457268
Effect of Transcutaneous Auricular Trigeminal Nerve Stimulation on Migraine
Phase 3Ended 13 Jun 2026
Completed170 participants
NCT04069897
Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Migraine
Phase 3Ended 2 Jun 2026
Completed545 participants
NCT05748483
Comparative Study of Oral Atogepant Versus Oral Topiramate to Assess Adverse Events in Adult Participants With Migraine
No phaseEnded 1 Jun 2026
Completed178 participants
NCT06692881
Study to Assess Function and Satisfaction of Oral Ubrogepant in Adult Participants After Multiple Migraine Attacks In Canada
No phaseEnded 30 May 2026
Completed30 participants
NCT06695156
Exploring the Effect of the Transcendental Meditation® Technique on Migraine Frequency, Intensity, and Functionality: A Single-Arm Study
Phase 1/2Ended 26 May 2026
Completed29 participants
2025-521520-29-00
The headache-inducing effects of cilostazol in men and women with migraine without aura
No phaseEnded 15 May 2026
No phaseEnded 6 May 2026
Completed224 participants
NCT04936321
Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial
Phase 2Ended 6 May 2026
No phaseEnded 5 May 2026
Completed31 participants
NCT06841627
Osteopathic Manual Therapy (OMT) and Brain Structure and Function in Primary Headache Patients: A Pilot Study
No phaseEnded 1 May 2026
Completed228 participants
NCT07554664
Central Sensitization, Work-Related Stress, and Musculoskeletal Symptoms in Desk-Based Workers With and Without Migraine
- Central sensitization, work-related stress, and musculoskeletal pain symptoms in desk-based workers with and without migraine: a cross-sectional study. · The journal of headache and pain, 2026
No phaseEnded 1 May 2026
Completed217 participants
NCT06894121
Comparing Unilateral and Bilateral Proximal GONPRF in Migraine Treatment
Phase 3Ended 30 Apr 2026
No phaseEnded 30 Apr 2026
Completed40 participants
NCT03157739
MigraineManager: An Individualized Self-Management Tool for Adolescents With Migraine
No phaseEnded 15 Apr 2026
Completed332 participants
NCT07487701
Migraine Prevention With the Remote Electrical Neuromodulation (REN) Wearable: A Real-world Evidence Study
No phaseEnded 1 Apr 2026
Completed130 participants
NCT06409845
Effectiveness and Tolerability of Eptinezumab
- Levels of migraine controls following International Headache Society (IHS) recommendations with eptinezumab: Effectiveness and tolerability in a 24-week, prospective multicenter study (the TACHIS study). · Cephalalgia : an international journal of headache, 2026
No phaseEnded 1 Apr 2026
Completed21 participants
NCT05175521
Inhaled IAV vs Inhaled Eucalyptus for the Treatment of Nausea With Acute Migraine
No phaseEnded 31 Mar 2026
No phaseEnded 31 Mar 2026
Completed30 participants
NCT07035197
Facilitators and Barriers to Eptinezumab Administration in Thailand
No phaseEnded 31 Mar 2026
No phaseEnded 30 Mar 2026
No phaseEnded 18 Mar 2026
Completed57 participants
NCT06899074
Omega-3 Supplementation for Pediatric Migraine
- Omega-3 Supplementation with Lipid Biomarker Assessment in Youth with Migraine: A Quasi-Randomized Controlled Feasibility Trial. · medRxiv : the preprint server for health sciences, 2026
Phase 2Ended 16 Mar 2026
Completed874 participants
NCT06323928
A Dose-finding Trial With Lu-AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Treatments
No phaseEnded 15 Mar 2026
No phaseEnded 1 Mar 2026
No phaseEnded 28 Feb 2026
Completed213 participants
NCT07469748
Health Belief Model Scale Development for Disability and Abilities in Vestibular Migraine Patients
No phaseEnded 1 Feb 2026
Completed40 participants
NCT07493005
Virtual Reality-Based Vestibular Rehabilitation in Vestibular Migraine
- Virtual Reality-Based Vestibular Rehabilitation for Vestibular Migraine: A Randomized Trial. · The Laryngoscope, 2026
No phaseEnded 1 Feb 2026
Phase 4Ended 30 Jan 2026
Completed466 participants
NCT07336420
Treatment Patterns Among US Veterans Using Remote Electrical Neuromodulation (REN) for Migraine Treatment
No phaseEnded 30 Jan 2026
Completed60 participants
NCT07442916
Non-Invasive Brain Stimulation as Add-on Treatment in Chronic Migraine With Medication Overuse
No phaseEnded 28 Jan 2026
Completed226 participants
NCT05827887
An Observational Study to Assess Ubrogepant Tablets and Atogepant Tablets to Treat Migraine in Adult Participants
No phaseEnded 21 Jan 2026
Completed24 participants
NCT06862674
Clinical Exploration of NEUROMARK System in Participants With Chronic Migraine
No phaseEnded 14 Jan 2026
Phase 3Ended 7 Jan 2026
Completed284 participants
NCT03832998
Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic Migraine
No phaseEnded 1 Jan 2026
No phaseEnded 31 Dec 2025
No phaseEnded 30 Dec 2025
Phase 3Ended 22 Dec 2025
Completed499 participants
NCT04530110
A Trial to Test if Fremanezumab is Effective in Preventing Migraine in Children and Adolescents
No phaseEnded 19 Dec 2025
Completed51 participants
NCT06540235
The Effect of Bone-Conducted Stimulation on Rotary Chair Time Constants in Patients With Vestibular Migraines
No phaseEnded 15 Dec 2025
Completed30 participants
NCT07067853
Effectivity and Safety of GB20 Acupoint Pharmacopuncture With Lidocaine 2% on Migraine Patients
No phaseEnded 15 Dec 2025
Phase 3Ended 10 Dec 2025
Completed787 participants
NCT05810038
A Study to Learn About the Safety and Effects of Rimegepant to Prevent Migraine in Chinese Subjects.
Phase 3Ended 4 Dec 2025
Completed175 participants
NCT04396574
A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine (PIONEER-PEDS2)
No phaseEnded 1 Dec 2025
Completed100 participants
NCT05903040
Ditan Acute tReatments: Effectiveness and Tolerability (DART)
- Effectiveness and safety of lasmiditan and rimegepant in the acute migraine treatment: an indirect real-world comparison. · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2026
- Effectiveness and tolerability of lasmiditan in the acute treatment of migraine: a real-world, prospective, multicentric study (DART study). · Therapeutic advances in neurological disorders, 2025
No phaseEnded 30 Nov 2025
Completed44 participants
NCT07003711
Effects of Progressive Muscle Relaxation Training Applied in Addition to Aerobic Exercise Training in Individuals With Migraine Diagnosis
No phaseEnded 30 Nov 2025
Not medical advice. fetched 6 Nov 2026