Frontotemporal dementia trials in United States

In United States 53 Also abroad 110

53 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Early phase 1Taking people
Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia
Where
Austin
Age
18 years and over
People
120
Run by
University of Texas at Austin
See details and how to joinNCT06511752
Phase 2Taking people
Communication Bridge 3 Study
Where
Chicago
Age
18 years to 100 years
People
200
Run by
University of Chicago
See details and how to joinNCT06191198
Phase 2Taking people
Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia
Where
Baltimore, Philadelphia
Age
50 years to 90 years
People
180 worldwide
Run by
Johns Hopkins University
See details and how to joinNCT05386394
No phaseTaking people
The Neurobiology of Two Distinct Types of Progressive Apraxia of Speech
Where
Rochester
Age
18 years and over
People
47
Run by
Mayo Clinic
See details and how to joinNCT03313011
No phaseTaking people
Intervention for Communication Quality of Life in Primary Progressive Aphasia
Where
Austin
Age
40 years and over
People
30
Run by
Maya Henry
See details and how to joinNCT07219680
Phase 3Taking people
A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C
Where
Rochester
Age
4 years and over
People
53 worldwide
Run by
IntraBio Inc
See details and how to joinNCT05163288
Phase 2Taking people
Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal Dementia
Where
Baltimore
Age
45 years and over
People
50
Run by
Johns Hopkins University
See details and how to joinNCT06604520
No phaseTaking people
Language in Primary Progressive Aphasia
Where
Chicago
People
500
Run by
Northwestern University
See details and how to joinNCT00537004
No phaseEnrolling by invitation
Research Study for Patients With Neurological Diseases Which Evaluates the Patient Experience of the MemorEM Device
Where
Atlanta
Age
45 years to 100 years
People
1,000
Run by
eQ8Health Corporation d/b/a CareONE Concierge
See details and how to joinNCT07222605
No phaseTaking people
Retinal Imaging in Neurodegenerative Disease
Where
Durham
Age
18 years and over
People
2,000
Run by
Duke University
See details and how to joinNCT03233646
No phaseTaking people
UPenn Observational Research Repository on Neurodegenerative Disease
Where
Philadelphia
Age
18 years and over
People
1,000
Run by
University of Pennsylvania
See details and how to joinNCT04715399
Early phase 1Taking people
Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183A
Where
Philadelphia, San Francisco
Age
40 years to 85 years
People
90
Run by
University of Pennsylvania
See details and how to joinNCT06932809
No phaseEnrolling by invitation
Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders
Where
Rochester
Age
21 years and over
People
500
Run by
Mayo Clinic
See details and how to joinNCT04680130
Phase 4Taking people
Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech
Where
Rochester
Age
18 years and over
People
50
Run by
Mayo Clinic
See details and how to joinNCT01818661
No phaseTaking people
STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care Partners
Where
Portland
Age
18 years to 100 years
People
640
Run by
Oregon Health and Science University
See details and how to joinNCT06613204
No phaseEnrolling by invitation
Speech-Language Treatment With Remotely Supervised Transcranial Direct Current Stimulation in Primary Progressive Aphasia
Where
Austin, San Francisco
People
10
Run by
University of Texas at Austin
See details and how to joinNCT05901233
No phaseEnrolling by invitation
Primary Progressive Aphasia Multicomponent Language Treatment Study
Where
Austin
People
21
Run by
University of Texas at Austin
See details and how to joinNCT06649084
No phaseTaking people
Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
Where
Irvine
Age
18 years and over
People
50
Run by
University of California, Irvine
See details and how to joinNCT01353430
Phase 1/2Taking people
First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia
Where
San Francisco
Age
40 years to 75 years
People
102
Run by
David Wilson
See details and how to joinNCT05374278
No phaseTaking people
ALS Research Collaborative
Where
Watertown
Age
18 years and over
People
2,000
Run by
ALS Therapy Development Institute
See details and how to joinNCT06885918
No phaseTaking people
NYSCF Scientific Discovery Biobank
Where
New York
Age
30 days and over
People
10,000
Run by
New York Stem Cell Foundation Research Institute
See details and how to joinNCT06203106
No phaseEnrolling by invitation
BioFINDER-Brown: Examination of Alzheimer's Disease Biomarkers
Where
Providence
Age
50 years to 80 years
People
200
Run by
Butler Hospital
See details and how to joinNCT05457998
No phaseTaking people
Enhancing Language Function in Aphasia
Where
Tucson
Age
21 years to 80 years
People
30
Run by
University of Arizona
See details and how to joinNCT05443633
No phaseTaking people
Enhancing Language Function in Primary Progressive Aphasia
Where
Tucson
Age
45 years to 80 years
People
20
Run by
University of Arizona
See details and how to joinNCT04920318
No phaseTaking people
Longitudinal Cognitive Assessment by BoCA
Where
Miami
Age
50 years and over
People
10,000
Run by
Alzheimer's Light LLC
See details and how to joinNCT04114994