Obesity trials in United States

In United States 744 Also abroad 1939

744 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease
Where
Lexington
Age
12 years to 17 years
People
50
Run by
Oelisoa Andriankaja
See details and how to joinNCT07478653
Phase 2Taking people
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
Where
Amherst, Ammon, Austin, Chandler, Chicago, Cincinnati, City of Saint Peters, Dallas, Danville, Greenbrae, Greensboro, Greenville, Houston, Huntington Park, Las Vegas, Louisville, Miami, Miami Lakes, Monroe, Morehead City, Nashville, Needham, New Bedford, New Bern, New Port Richey, Orlando, Rochester, Rolling Hills Estates, San Antonio, Scottsdale, Southfield, Springfield, Stamford, The Villages, Topeka, Troy, Tucson, Walnut Creek, Wenatchee, Weslaco
Age
18 years to 75 years
People
400
Run by
Eli Lilly and Company
See details and how to joinNCT07589608
Phase 1Taking people
A Study of Eloralintide (LY3841136) in Female Participants With Obesity or Overweight
Where
Dallas, Daytona Beach
Age
18 years to 60 years
People
34
Run by
Eli Lilly and Company
See details and how to joinNCT07808060
Phase 1Taking people
A Study of LY4329090 in Participants With Obesity or Overweight Who Are Otherwise Healthy
Where
Dallas, Daytona Beach
Age
18 years to 65 years
People
184 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07808073
No phaseTaking people
New Heart Imaging Techniques to Evaluate Possible Heart Disease
Where
Bethesda
Age
18 years to 100 years
People
4,000
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT01399385
No phaseTaking people
Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery
Where
Houston
Age
18 years and over
People
80
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT04003038
No phaseTaking people
Breathing & Blood Pressure
Where
Tallahassee
Age
18 years to 45 years
People
80
Run by
Florida State University
See details and how to joinNCT05632406
Phase 2Taking people
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
Where
Amherst, Ammon, Austin, Chandler, Chicago, Cincinnati, City of Saint Peters, Dallas, Danville, East Syracuse, Fleming Island, Greenbrae, Greensboro, Greenville, Honolulu, Houston, Huntington Park, Las Vegas, Louisville, Miami, Miami Lakes, Monroe, Morehead City, Nashville, Needham, New Bedford, New Bern, New Port Richey, Orlando, Phoenix, Port Jefferson Station, Rochester, Rolling Hills Estates, San Antonio, Scottsdale, Skokie, Southfield, Springfield, Stamford, The Villages, Topeka, Troy, Tucson, Walnut Creek, Wenatchee, Weslaco, West Des Moines
Age
18 years to 75 years
People
1,481 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06143956
Phase 2Taking people
Phentermine's Impact on Treatment in Teens
Where
Albuquerque, Baton Rouge, Columbia, Kansas City, Lebanon, Louisville, Oklahoma City, Wilmington
Age
12 years to 17 years
People
240
Run by
Russell McCulloh, MD
See details and how to joinNCT07282340
No phaseTaking people
Respiratory Muscle Training to Improve Cerebrovascular and Immune Function
Where
Tallahassee
Age
18 years to 45 years
People
30
Run by
Florida State University
See details and how to joinNCT07406295
Phase 3Taking people
AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
Where
Atlanta, Bradenton, Chicago, Cincinnati, Columbia, DeSoto, DuBois, El Paso, Fargo, Gilbert, Houston, Lawrenceville, Naples, New York, Renton, San Antonio, Seattle, Sugar Land, West Palm Beach
Age
18 years and over
People
300 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07571109 · EU 2024-520443-16-00
Phase 3Taking people
A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Established Cardiovascular Disease
Where
Anniston, Los Angeles, Port Orange
Age
40 years and over
People
2,500 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07843472 · EU 2026-526190-41-00
Phase 1Taking people
Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)
Where
Miami, Salt Lake City, San Antonio
Age
18 years to 65 years
People
134
Run by
Gilead Sciences
See details and how to joinNCT06562907
Phase 4Taking people
The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity
Where
Jacksonville
Age
46 years to 60 years
People
40
Run by
Mayo Clinic
See details and how to joinNCT07218445
Phase 3Not yet taking people in United States
A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular Disease and Either Overweight or Obesity
Where
Albany, Amarillo, Austin, Avon, Baltimore, Beaumont, Beaver, Beverly Hills, Birmingham, Bossier City, Bountiful, Bowie, Bridgeport, Bristol, Carrollton, Chesterfield, Chula Vista, Cincinnati, Clearwater, Columbia, Conroe, Conyers, Cordele, Corpus Christi, Council Bluffs, Covina, Covington, Crystal River, Dallas, Delray Beach, Detroit, Durham, Fairhope, Fargo, Flint, Fort Mill, Franklin, Gilbert, Gillespie, Glendale, Green Bay, Greenfield, Greensboro, Greenville, Gurnee, Harlingen, Hazel Crest, Hollywood, Houston, Idaho Falls, Iowa City, Jacksonville, Johns Creek, Kansas City, Kingsport, Lakeland, Lancaster, Las Vegas, Layton, Lexington, Lomita, Longview, Los Alamitos, Los Angeles, Louisville, Lufkin, Macon, Maitland, Manassas, Manlius, Maumee, Mesquite, Miami, Miami Lakes, Mobile, Moline, Montgomery, Moore, Morehead City, Moultrie, Mt. Pleasant, Muncie, Myrtle Beach, Naples, Nashville, Newport, Newport News, New Port Richey, New Windsor, New York, Norfolk, Norman, Northridge, Oak Brook, Ocala, Omaha, Oviedo, Palm Beach Gardens, Palm Harbor, Palm Springs, Peachtree City, Pembroke Pines, Peoria, Philadelphia, Portsmouth, Richmond, Riverview, Round Rock, Sacramento, Salem, San Antonio, San Diego, San Dimas, Santa Maria, Schaumburg, Scottsdale, Slidell, Spokane, Springfield, Statesville, St Louis, Sugar Land, Surprise, Tamarac, The Bronx, Tomball, Topeka, Troy, Tucker, Victoria, Vienna, Wellington, West Des Moines, Westfield, West Valley City, Winchester, Ypsilanti
Age
45 years to 64 years
People
8,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07861100 · EU 2026-525182-53-00
No phaseTaking people
GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study
Where
Birmingham
Age
18 years and over
People
200
Run by
University of Alabama at Birmingham
See details and how to joinNCT05216042
No phaseTaking people
Efficacy of mHealth Applications in Weight Management in a Population Affected by Overweight or Obesity
Where
San Diego
Age
18 years to 64 years
People
30
Run by
San Diego State University
See details and how to joinNCT05726942
Phase 2/3Taking people
Food-Body-Mind Intervention (16 Weeks)
Where
Jackson
Age
3 years to 5 years
People
800
Run by
Michigan State University
See details and how to joinNCT06597474
No phaseTaking people
Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans
Where
Aurora
Age
18 years to 75 years
People
132
Run by
VA Office of Research and Development
See details and how to joinNCT06627569
Phase 3Taking people
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
Where
Annapolis, Austin, Bellaire, Burke, Canoga Park, Cerritos, Cincinnati, Corpus Christi, Denison, East Greenwich, Gilbert, Kansas City, La Mesa, Las Vegas, Lenexa, Miami, Miami Lakes, Modesto, Monroe, Morehead City, Newton, Orlando, Pomona, Skokie, Trenton, West Des Moines, Weston, Wichita, Winter Park
Age
18 years to 99 years
People
950 worldwide
Run by
Amgen
See details and how to joinNCT07684144 · EU 2025-524788-19-00
Phase 3Taking people
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
Where
Anniston, Arlington, Austin, Baton Rouge, Bellaire, Binghamton, Bountiful, Chicago, Cincinnati, Dallas, Daphne, DeSoto, East Greenwich, El Paso, Fayette, Fountain Valley, Gainesville, Greenville, Hickory, Honolulu, Houston, Jacksonville, Kansas City, Knoxville, Las Vegas, Lauderhill, Layton, Lenexa, Long Beach, Louisville, Marrero, Meridian, Mesquite, Miami, Miami Lakes, Mobile, Montclair, Newport, Newport News, Newton, Norman, Ocala, Orlando, Pharr, Riverside, Rochester, San Antonio, San Diego, Santa Ana, Shelby, Skokie, Southfield, St. George, Sugar Land, Union City, Walnut Creek, Waterbury, Wauwatosa, Weston, Winchester
Age
18 years to 99 years
People
3,200 worldwide
Run by
Amgen
See details and how to joinNCT07684235
No phaseTaking people
A Trial to Examine the Effects of a Weight Loss Program Emphasizing Protein, Dietary Fiber, and Exercise (30-30-30 Plan)
Where
Addison, Bloomington, Chicago
Age
18 years to 69 years
People
110
Run by
Midwest Center for Metabolic and Cardiovascular Research
See details and how to joinNCT07789769
No phaseTaking people
Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population
Where
San Diego
Age
18 years to 64 years
People
45
Run by
San Diego State University
See details and how to joinNCT05279729
No phaseEnrolling by invitation
Dietary Sugar Absorptive Phenotype for Prediction of Weight Loss Outcome
Where
Jacksonville
Age
18 years and over
People
52
Run by
Mayo Clinic
See details and how to joinNCT05408728
No phaseTaking people
Efficacy of Using Mobile Health Applications for Health
Where
San Diego
Age
18 years to 64 years
People
30
Run by
San Diego State University
See details and how to joinNCT05589155