Epilepsy: trials for referral
505 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Where the open trials are
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400 trials shown · Showing the 400 most recently updated of 505 open trials.
No phase1 site
RecruitingUnited States
NCT02824822
Genetic Markers of Cardiovascular Disease in Epilepsy
Mayo Clinic
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase0 sites
Not yet recruiting
NCT07903168
Why Do People With Epilepsy Get More Infections?
University of Aberdeen
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT00060541
Evaluation and Treatment of Neurosurgical Disorders
National Institute of Neurological Disorders and Stroke (NINDS)
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingSouth Korea
NCT07912931
Electrophysiological Dose-Response to Anterior Thalamic Deep Brain Stimulation in Drug-Resistant Focal Epilepsy
Yonsei University
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 1/27 sites
RecruitingCanada, United States
NCT07531745
ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome
Ionis Pharmaceuticals, Inc.
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingBelgium
NCT07909486
Identification of Biomarkers for Vagus Nerve Stimulation in Patients With Refractory Epilepsy
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govNo phase0 sites
Not yet recruiting
NCT07909460
Blood Brain Barrier Dysfunction in Glioma and Epileptogenesis
University College, London
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT07735715
HOBSCOTCH-YOUTH and Young Adults
Dartmouth-Hitchcock Medical Center
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 3102 sites
RecruitingArgentina, Austria, Australia, Belgium, Bulgaria, Chile
NCT05716100
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
Xenon Pharmaceuticals Inc.
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 3173 sites
By invitation onlyArgentina, Austria, Australia, Belgium, Bulgaria, Canada
NCT05718817
An Open-label Study of XEN1101 in Epilepsy
Xenon Pharmaceuticals Inc.
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 3129 sites
RecruitingArgentina, Austria, Australia, Belgium, Bulgaria, Canada
NCT05667142
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Xenon Pharmaceuticals Inc.
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT05989893
Mapping of Human Cognition
The University of Texas Health Science Center, Houston
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 2/323 sites
RecruitingUnited States
NCT07723963
A Study to Evaluate the Safety and Efficacy of JZP926 Capsule for the Treatment of Juvenile Myoclonic Epilepsy
Jazz Pharmaceuticals
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingBelgium
NCT06304389
Effect of Blue Light on Vagus Nerve Stimulation in Patients With Refractory Epilepsy
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govNo phase14 sites
RecruitingBelgium, Germany, Denmark, Spain, France, Israel
NCT07909382
Multi-biomarkers in DEE
Istituto Giannina Gaslini
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingEgypt
NCT07135713
Electrocardiographic Changes Associated With Epilepsy
Assiut University
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingUnited States
NCT07520955
Lily's Grace Temporal Interference
University of Wisconsin, Madison
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govPhase 336 sites
RecruitingUnited States
NCT05135091
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
Neurona Therapeutics
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingChina
NCT07458217
Combined CM and STN Stimulation for Motor Epilepsy
Boston Scientific Corporation
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govPhase 386 sites
RecruitingArgentina, Brazil, Canada, China, Spain, United Kingdom
NCT04462770
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
Epygenix
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govPhase 11 site
RecruitingUnited States
NCT02531880
Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy
National Institute of Neurological Disorders and Stroke (NINDS)
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govNo phase0 sites
Not yet recruiting
NCT07904039
Characterisation of Laryngeal Evoked Potentials Induced by Vagus Nerve Stimulation in Refractory Epilepsy Patients
Université Catholique de Louvain
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govPhase 344 sites
RecruitingGermany, Spain, Italy, Poland
2025-521640-38-00
Open Label Extension Clinical Trial of Vormatrigine in Adult Patients with Epilepsy.
Praxis Precision Medicines Inc.
Registry updated 29 Oct 2026
Registry record: EU CTISPhase 43 sites
RecruitingIndia
NCT07072624
Early Post-Traumatic Seizures Prevention Trial (E-PTS Trial)
All India Institute of Medical Sciences, Jodhpur
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingUnited States
NCT07803692
High-Intensity Focused Ultrasonic Ablation of the Centromedian Thalamic Nucleus for Treatment of Medically Refractory Generalized Epilepsy in Patients Ages 18 Years to 89 Years
Oregon Health and Science University
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT06974305
PET/MRI/EEG Imaging Study in Epilepsy
Massachusetts General Hospital
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT01793168
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Sanford Health
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingFrance
NCT07898397
Long-Term Epilepsy Outcomes in Children With a History of Perinatal Stroke
University Hospital, Strasbourg, France
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
By invitation onlyUnited States
NCT04095026
Study of Direct Brain Recording and Stimulation for Memory Enhancement
National Institute of Neurological Disorders and Stroke (NINDS)
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govPhase 211 sites
By invitation onlyAustralia, Bulgaria, Hungary, Poland, United States
NCT07141329
SPN-817 Open-Label Extension Study in Adults With Focal Onset Seizures
Supernus Pharmaceuticals, Inc.
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.gov
The same sites as a list
- United States188 open trials
- France63 open trials
- China30 open trials
- Italy28 open trials
- Spain21 open trials
- Australia20 open trials
- United Kingdom19 open trials
- Canada18 open trials
- Poland18 open trials
- Germany15 open trials
- Belgium13 open trials
- Netherlands13 open trials
- Hungary10 open trials
- Mexico9 open trials
- Czechia9 open trials
- Switzerland8 open trials
- Sweden8 open trials
- Bulgaria7 open trials
- Japan7 open trials
- Brazil7 open trials
- Portugal6 open trials
- Argentina6 open trials
- Israel6 open trials
- Taiwan6 open trials
- Denmark5 open trials
- South Korea4 open trials
- Austria4 open trials
- Chile4 open trials
- Croatia4 open trials
- Finland4 open trials
- Egypt4 open trials
- India4 open trials
- Greece4 open trials
- Serbia3 open trials
- Romania3 open trials
- Norway3 open trials
- Latvia2 open trials
- South Africa2 open trials
- Russia2 open trials
- Bangladesh2 open trials
- New Zealand1 open trials
- Georgia1 open trials
- Singapore1 open trials
- Uganda1 open trials
- Pakistan1 open trials
- Zambia1 open trials
- Kenya1 open trials
- Slovakia1 open trials
- Hong Kong SAR China1 open trials
- Saudi Arabia1 open trials
- Estonia1 open trials
- Colombia1 open trials
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
Cincinnati Children's Hospital Medical Center
Cincinnati, United States
9 trials · 105 publications · ROR
Florey Institute of Neuroscience and Mental Health
Melbourne, Australia
0 trials · 101 publications · ROR
National Hospital for Neurology and Neurosurgery
London, United Kingdom
1 trials · 81 publications · ROR
Rutgers, The State University of New Jersey
New Brunswick, United States
0 trials · 69 publications · ROR
The University of Texas Health Science Center at Houston
Houston, United States
9 trials · 128 publications · ROR
The University of Texas Southwestern Medical Center
Dallas, United States
0 trials · 145 publications · ROR
University Hospitals Cleveland Medical Center
Cleveland, United States
5 trials · 68 publications · ROR
University of Arkansas for Medical Sciences
Little Rock, United States
3 trials · 77 publications · ROR
University of California, San Francisco
San Francisco, United States
19 trials · 220 publications · ROR
University of North Carolina at Chapel Hill
Chapel Hill, United States
7 trials · 95 publications · ROR
What changed in the last 7 days
Registry facts, one per line, newest first.
No registry change in the last 7 days.
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
Phase 3Ended 7 Oct 2026
Completed60 participants
2025-524038-24-00
A Double-blind, Randomized Clinical Trial Evaluating the Efficacy and Safety of Vormatrigine in Adults with Focal Seizures
Phase 3Ended 2 Oct 2026
Completed154 participants
NCT05067634
Safety and Efficacy Study of Cenobamate in Pediatric Subjects 2-17 Years of Age With Partial-onset (Focal) Seizures
Phase 2Ended 1 Oct 2026
Completed10 participants
NCT05727943
Add-on Clioquinol in Drug-resistant Childhood Epilepsy: an Exploratory Study
Phase 2Ended 23 Sept 2026
Completed14 participants
NCT06769659
A Study Evaluating NPT 2042 Versus Placebo in Subjects Aged 16-75 Years With Genetic Generalized Epilepsy (GGE) and Absence Seizures
Phase 1Ended 16 Sept 2026
Phase 3Ended 1 Sept 2026
Phase 1Ended 31 Aug 2026
Completed48 participants
2025-524310-28-00
A Study Evaluating the Safety and Tolerability of a Novel Formulation of QRL-101 in Healthy Participants
No phaseEnded 12 Aug 2026
Completed5 participants
NCT06340802
A First in hUman Study for Resistant Epilepsy With the Vagus Nerve stimulatiOn Device by syneRgia medicAl
No phaseEnded 8 Jul 2026
Phase 3Ended 7 Jul 2026
No phaseEnded 30 Jun 2026
Phase 3Ended 10 Jun 2026
Phase 2Ended 8 Jun 2026
Completed12 participants
NCT05019885
The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy
No phaseEnded 1 Jun 2026
No phaseEnded 31 May 2026
Phase 3Ended 27 May 2026
No phaseEnded 25 May 2026
No phaseEnded 19 May 2026
No phaseEnded 6 May 2026
Completed61 participants
NCT06315829
Artificial Intelligence-based Video Analysis to Detect Infantile Spasms
Phase 2/3Ended 22 Apr 2026
Completed170 participants
2024-514559-13-00
A Double-Blind, Randomized, Multicenter, Trial Evaluating the Efficacy and Safety of PRAX-628 in Adults with Focal Seizures (POWER 1)
No phaseEnded 13 Apr 2026
Completed70 participants
NCT07540013
The Effect of Mandala Coloring on the Quality of Life in Epilepsy Patients: A Single Blind Randomized Controlled Study
No phaseEnded 1 Apr 2026
No phaseEnded 1 Apr 2026
No phaseEnded 1 Apr 2026
Completed90 participants
NCT07449845
Quality of Life Assessment in Patients With Epilepsy Using QOLIE-31
No phaseEnded 31 Mar 2026
No phaseEnded 31 Mar 2026
Completed1100 participants
NCT06790810
Observational Study on Dynamic Changes of Blood Pressure During Post-epileptic Seizure Stage (OCBPS)
No phaseEnded 31 Mar 2026
Completed13 participants
NCT01590862
ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators
Phase 2/3Ended 12 Mar 2026
Completed122 participants
NCT06425159
Efficacy, Safety and Tolerability of BHV-7000 in Subjects with Idiopathic Generalized Epilepsy with Generalized Tonic-clonic Seizures – SHINE
Phase 1Ended 18 Feb 2026
Completed4 participants
NCT06387186
Leucine Enriched Essential Amino Acid Powder as an Add-on to a Classic Ketogenic Diet in Refractory Epilepsy
No phaseEnded 18 Feb 2026
Phase 2Ended 10 Feb 2026
Phase 3Ended 3 Feb 2026
Completed380 participants
NCT05614063
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures
No phaseEnded 31 Jan 2026
No phaseEnded 31 Jan 2026
Completed150 participants
NCT05606575
A Study of Detection of Paroxysmal Events Utilizing Computer Vision and Machine Learning - Nelli
No phaseEnded 31 Jan 2026
Completed33 participants
NCT06705439
A Study of Detection of Paroxysmal Events Utilizing Computer Vision and Machine Learning (USF)
No phaseEnded 30 Jan 2026
Phase 4Ended 20 Jan 2026
Completed137 participants
NCT07422233
Evaluation of Levetiracetam's Effectiveness and Tolerability for Treating Epilepsy in Older Adults
No phaseEnded 19 Jan 2026
Completed530 participants
NCT06546410
OASIS: RetrOspective Analysis on EEGs for Identifying Seizure Susceptibility in paediatrIcs Using biomarkerS
Phase 2Ended 14 Jan 2026
Completed20 participants
2024-511388-27-04
Add-on Clioquinol in drug-resistant epilepsy: an exploratory study
No phaseEnded 12 Jan 2026
Completed127 participants
NCT04770337
Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy
No phaseEnded 9 Jan 2026
Completed30 participants
NCT02263274
Direct Cortical Measurement of the Intensity and Pattern of Current Flow Produced by TDCS
No phaseEnded 15 Dec 2025
Completed70 participants
NCT06120101
Reflexology on Seizure Frequency, Fatigue, Stress and Sleep Quality in Epilepsy Patients
Phase 2Ended 3 Dec 2025
Completed50 participants
2024-515950-25-00
Open-label study to assess safety and efficacy of rapamycin in drugresistant epilepsy associated with mTOR pathway pathologies
No phaseEnded 1 Dec 2025
Phase 2Ended 7 Nov 2025
Completed35 participants
2024-517061-16-01
An Open Label Clinical Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adult Patients with Focal Onset or Primary Generalized Tonic-Clonic Seizures
No phaseEnded 7 Nov 2025
Phase 1Ended 6 Nov 2025
Completed26 participants
NCT04903314
Dose-Escalation Study of Cenobamate (YKP3089) in Pediatric Subjects With Partial-Onset Seizures
Phase 1Ended 5 Nov 2025
Completed50 participants
2024-517638-16-00
18F-DPA714 PET-MRI study to improve preoperative localisation of the epileptic focus to be resected in drug-resistant partial epilepsy.
Phase 1Ended 4 Nov 2025
No phaseEnded 20 Oct 2025
No phaseEnded 1 Oct 2025
Completed60 participants
NCT06310772
Assessing Comorbidities in Epilepsy Using Eye Movement Recordings
No phaseEnded 30 Sept 2025
Completed8 participants
NCT06447675
Efficacy and Safety Evaluation of Hyperthermic Baths in the Treatment of Seizures in CDKL5 Deficiency Disorder
Phase 2Ended 26 Sept 2025
Completed30 participants
NCT06377930
Study Evaluating the Safety and Efficacy of RAP-219 in Adult Participants With Refractory Focal Epilepsy
No phaseEnded 22 Sept 2025
Completed455 participants
NCT06714448
A Study of the Effectiveness of Risk Minimization Measures Related to Depakine® (Sodium Valproate) in Saudi Arabia
No phaseEnded 15 Sept 2025
Phase 4Ended 30 Aug 2025
Phase 1Ended 27 Aug 2025
Completed24 participants
NCT07176832
Bioavailability of Stiripentol After Single Oral Dose of Capsule vs Suspension in Healthy Subjects (STILIQ)
No phaseEnded 26 Aug 2025
Completed4 participants
NCT05437393
Children's Adaptive Deep Brain Stimulation for Epilepsy Trial (CADET): Pilot
No phaseEnded 5 Aug 2025
Completed117 participants
NCT06960811
Epileptic Psychoses and Their Link With Ictal Emotions and Consciousness
Phase 2Ended 4 Aug 2025
Completed13 participants
NCT06412653
Prospective Pilot Trial to Address Feasibility and Safety of Oral Zinc in GNAO1 Associated Disorders
Not medical advice. fetched 4 Nov 2026