For volunteers

Healthy volunteer studies in Australia

112 open studies in the registries that take healthy volunteers and have a site in Australia.

Phase 1Starts 1 Nov 2026
Ages 18 to 65All sexes96 participants
NCT07904689
A Study of NOR-101 in Healthy Adults and Adults With Moderate-to-Severe Atopic Dermatitis
Adelaide · North Immunology Inc.
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 15 Nov 2026
From age 18All sexes96 participants
NCT07903779
Effects of Smartphone Use and Television Viewing on Standardized BP Measurement: The SCREENS-BP Study
Camperdown · Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 1 Dec 2026
Ages 18 to 55All sexes40 participants
NCT07900568
Study of HXN-1013 in Healthy Participants and Participants With Mild-to-Moderate Asthma
Bayswater · Helixon Biotechnology (Suzhou) Co., Ltd
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 1 Nov 2026
Ages 18 to 65All sexes40 participants
NCT07873229
DDI Study of ECC0509 With Metformin, Midazolam, and Caffeine
Melbourne · Eccogene
Registry updated 14 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 1 Oct 2026
Ages 18 to 65All sexes70 participants
NCT07869225
A Phase I, Randomized, Double-Blind, Placebo-Controlled Study of EQ504 in Single and Multiple Ascending Doses in Healthy Volunteers
Melbourne · Equillium
Registry updated 9 Oct 2026
Registry record: ClinicalTrials.gov
Phase 4Starts 1 Oct 2026
From age 30All sexes20 participants
NCT07850466
TRPTI Metabolic and GLP-1 Pharmacodynamic Study
Fortitude Valley · RDC Clinical Pty Ltd
Registry updated 30 Sept 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Nov 2026
Ages 18 to 85All sexes320 participants
NCT07813013
Right Colon Enema to Improve Bowel Preparation Quality During Colonoscopy
Westmead, Auburn · Westmead Hospital
Registry updated 24 Sept 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2026
From age 18All sexes6000 participants
NCT07822022
Implementing Improved Blood Pressure Measurement in General Practice: A Multisite Implementation Trial Using Automated Office Blood Pressure (AOBP)
Hobart · Menzies Institute for Medical Research
Registry updated 16 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 30 Sept 2026
Ages 18 to 60All sexes46 participants
NCT07776041
A Study of SYH2092 Injection in Healthy Participants
Melbourne · CSPC Megalith Biopharmaceutical Co.,Ltd.
Registry updated 20 Aug 2026
Registry record: ClinicalTrials.gov
Phase 4Starts 12 Oct 2026
From age 18All sexes150 participants
NCT07733453
Baerveldt Versus Paul Study
Melbourne, Sydney · University of Sydney
Registry updated 3 Aug 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 1 Jul 2026
Ages 18 to 60All sexes64 participants
NCT07724431
A Phase 1, Double-blind, Randomized Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of Single Dose and Multiple Doses of CG-0416 in Healthy Participants.
Melbourne · HongKong Curegene Innovation Co., Limited
Registry updated 24 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 15 Aug 2026
Ages 18 to 55All sexes72 participants
NCT07690228
A Study of GSM-779690T in Healthy Adult Participants
Melbourne · Acta Pharmaceuticals
Registry updated 9 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 29 Jun 2026
Ages 18 to 65Men only74 participants
NCT07682337
Study of Single and Multiple Oral Doses of SCB0020160 in Healthy Adult Male Subjects
Adelaide · SCBIO Inc.
Registry updated 2 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 1 Jun 2026
Ages 18 to 70All sexes78 participants
NCT07557355
A Study of SRSD384 in Overweight or Obese Participants
Charlestown · Sirius Therapeutics Co., Ltd.
Registry updated 5 Jun 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Sept 2026
From age 18All sexes500 participants
NCT07569913
A Study to Evaluate the Performance, and Usability of TruPlex HIV/HepB/Syphilis Rapid Test
Melbourne · bioLytical Laboratories
Registry updated 6 May 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 27 May 2026
Ages 18 to 55All sexes28 participants
NCT07549750
A Dose Escalation Phase 1 Study of HXN5003 in Healthy Participants
Bayswater · Helixon Biotechnology (Suzhou) Co., Ltd
Registry updated 24 Apr 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 30 Aug 2025
Ages 18 to 55All sexes84 participants
NCT07143331
A Phase 1 Study to Assess the Safety and Effects of Single and Multiple Doses of KS101 in Healthy Volunteers
Sydney · Klotho Sciences Australia Pty Ltd.
Registry updated 27 Aug 2025
Registry record: ClinicalTrials.gov
Phase 1Starts 1 Sept 2025
Ages 18 to 65All sexes76 participants
NCT07140081
A Research Study to Evaluate BLX-0871 in Healthy Adults
Melbourne · Biolexis Therapeutics
Registry updated 24 Aug 2025
Registry record: ClinicalTrials.gov
Phase 1Starts 1 Sept 2025
Ages 18 to 65All sexes76 participants
NCT07140055
A Research Study to Evaluate BLX-7006 in Healthy Adults
Brisbane · Biolexis Therapeutics
Registry updated 24 Aug 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Nov 2025
From age 18All sexes26 participants
NCT07014241
Assessment of Whether Telehealth Family Psychoeducation for Major Depressive Disorder is Doable
Bakewell, Palmerston · University of Southern Queensland
Registry updated 10 Jun 2025
Registry record: ClinicalTrials.gov
Phase 1Starts 1 Feb 2025
Ages 18 to 45All sexes36 participants
NCT06772870
A Single Ascending Dose Study of DT-216P2 in Normal Healthy Participants
Melbourne · Design Therapeutics, Inc.
Registry updated 21 Feb 2025
Registry record: ClinicalTrials.gov
Phase 2Starts 14 Dec 2024
Ages 18 to 26Women only300 participants
NCT06681636
Effector and Memory Immune Responses to HPV Vaccination in Vietnamese Women Post Virus Exposure
Parkville · National Institute of Hygiene and Epidemiology, Vietnam
Registry updated 8 Nov 2024
Registry record: ClinicalTrials.gov
Phase 1Starts 30 Nov 2026
Ages 18 to 55All sexes32 participants
NCT07903493
Phase Ia Study of MST-931 in Healthy Adult Subjects
Herston · Mabsoft Therapeutics (Shanghai) Co., Ltd.
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.gov
No phaseStarts 12 May 2025
From age 50All sexes1000 participants
NCT06924021
Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)
Adelaide · University of Wisconsin, Madison
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 10 Oct 2024
Ages 18 to 75All sexes270 participants
NCT06619990
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Macquarie Park, Wollongong, Melbourne, Joondalup, Southport, Brisbane, Adelaide, South Brisbane · Xencor, Inc.
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 18 Sept 2020
Ages 18 to 90All sexes20000 participants
NCT04970056
Pancreatic Cancer Early Detection Consortium
Richmond · Arbor Research Collaborative for Health
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 5 Aug 2026
Ages 18 to 55All sexes64 participants
NCT07736586
A Study of HL40626S Tablets in Healthy Adults
Melbourne · HighsLab Therapeutics Inc.
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 2 May 2025
Ages 18 to 70All sexes115 participants
NCT06934252
Phase 1a/1b Study of TRB-061 in Healthy Participants & Patients With Atopic Dermatitis
Blacktown, Melbourne, Albion, Deakin, Kanwal, Adelaide, Coorparoo, Saint Albans · TRex Bio, Inc.
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 20 Oct 2026
Ages 18 to 65All sexes132 participants
NCT07850310
A Clinical Trial of MK-8644 in Healthy Participants and Participants With Psoriasis (MK-8644-001)
Melbourne · Merck Sharp & Dohme LLC
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 10 Apr 2026
Ages 18 to 65All sexes60 participants
NCT07532655
A Single Ascending Dose and Multiple Ascending Doses Study of SYH2082 Injection in Healthy Participants
Nedlands · CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 16 Apr 2026
Ages 18 to 55All sexes40 participants
NCT07479862
A Study of SA030 Injection in Overweight or Obese Participants
Adelaide, Brisbane · Suzhou Siran Biotechnology Co.,Ltd.
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 22 Jul 2026
Ages 18 to 65All sexes105 participants
NCT07712939
A Phase 1, First-in-Human Study of CND319 in Healthy Participants and Patients With Rheumatic Diseases
Melbourne · Candid Therapeutics
Registry updated 21 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 30 Nov 2023
Ages 18 to 75All sexes106 participants
NCT07630545
A Phase I Study in Healthy Volunteers and Parkinson's Disease (PD) Patients.
Adelaide, Melbourne · Mission Therapeutics
Registry updated 20 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 6 Jul 2026
Ages 18 to 60All sexes332 participants
NCT07628127
A Trial of Oral VRB-103 Alone or in Combination With Oral Ecnoglutide (VRB-101) in Participants With Obesity or Overweight
Melbourne, Brisbane · Verdiva Bio Dev Limited
Registry updated 13 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 24 Sept 2026
Ages 18 to 75All sexes63 participants
NCT07649265
A Trial in Healthy Adult Participants and Adults With Autoimmune Disease to Test How HBM7020 is Tolerated and Absorbed in the Body
Brisbane · Otsuka Pharmaceutical Development & Commercialization, Inc.
Registry updated 13 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 4 Feb 2026
Ages 18 to 55All sexes68 participants
NCT07276958
A Study of LY4298445 in Healthy Participants and Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)
Brisbane, Melbourne · Eli Lilly and Company
Registry updated 8 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 30 Oct 2025
Ages 18 to 75All sexes94 participants
NCT07231679
A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney Disease
Morayfield, Sydney, Gosford, Saint Albans, Herston · Ingenia Therapeutics INC
Registry updated 7 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 2009
From age 18All sexes700 participants
NCT00869817
Dominantly Inherited Alzheimer Network (DIAN)
Sydney, Melbourne, Perth · Washington University School of Medicine
Registry updated 5 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 17 Aug 2026
Ages 18 to 55All sexes56 participants
NCT07746817
A Study of BYN-001 in Healthy Adults and in Adults With Moderate to Severe Atopic Dermatitis
Melbourne · Bionyra Pharma
Registry updated 30 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 27 Feb 2025
Ages 18 to 72All sexes237 participants
NCT06808477
A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)
Perth, Fremantle · Bambusa Therapeutics
Registry updated 29 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 1 Oct 2026
Ages 18 to 65All sexes160 participants
NCT07826689
A Phase 1/2a Study of Oral PRO-1562 in Healthy Subjects and Patients With Relapsing Multiple Sclerosis
Adelaide · Progentos Therapeutics
Registry updated 29 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 6 Oct 2025
Ages 18 to 75All sexes176 participants
NCT07207954
Study of LFD-200 in Healthy Adults and Adults With Moderate to Severe Rheumatoid Arthritis
Melbourne · Lifordi Immunotherapeutics, Inc.
Registry updated 29 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 16 Jul 2024
Ages 30 to 89All sexes64 participants
NCT06466525
A Two-Part Single and Multiple Ascending Dose Trial of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LBT-3627 in Healthy Participants and in Participants With Parkinson's Disease.
Melbourne · Longevity Biotech Australia Pty Ltd (subsidiary)
Registry updated 25 Sept 2026
Registry record: ClinicalTrials.gov
Early Phase 1Starts 25 Feb 2025
Ages 18 to 79All sexes84 participants
NCT06813339
Placebo-controlled Study of Single and Multiple Ascending Doses of UDP-003 in Healthy Human Participants and Followed by an Open-label Patient Cohort
Melbourne, Adelaide, Camberwell · Cyclarity Therapeutics, Inc.
Registry updated 25 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 29 May 2026
Ages 18 to 55All sexes30 participants
NCT07615985
Phase 1a Study Assessing Safety, Tolerability, Pharmacokinetics, and Immunogenicity of PMG1016
Brisbane · Pulmongene Ltd.
Registry updated 23 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 1 Sept 2026
Ages 12 to 45All sexes48 participants
NCT07836452
A Phase 1, First-in-Human Study of CITY-RBP4 in Healthy Volunteers and STGD1 Participants
Melbourne · City Therapeutics
Registry updated 23 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 30 Dec 2025
Ages 18 to 75All sexes104 participants
NCT07230496
A Study to Investigate Safety, Tolerability and Pharmacokinetics of LAE103 or LAE103 in Combination With LAE102 in Healthy Overweight/Obese Participants
Sydney, Brisbane · Laekna Limited
Registry updated 21 Sept 2026
Registry record: ClinicalTrials.gov
No phaseStarts 4 Oct 2021
From age 1All sexes150000 participants
NCT05394363
Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents
Parkville · Murdoch Childrens Research Institute
Registry updated 17 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 7 Aug 2026
Ages 18 to 65All sexes40 participants
NCT07726368
Study of ECC4703 With Sulfasalazine and Pitavastatin
Melbourne · Eccogene
Registry updated 10 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 7 Jan 2026
Ages 18 to 65All sexes72 participants
NCT07334080
ECC4703 Food Effect and Relative Bioavailability Study in Healthy Adult Participants
Adelaide · Eccogene
Registry updated 10 Sept 2026
Registry record: ClinicalTrials.gov
No phaseStarts 28 Jun 2023
All sexes3000 participants
NCT06016946
Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study
Parkville · Friedreich's Ataxia Research Alliance
Registry updated 1 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 23 Jun 2026
Ages 18 to 65All sexes80 participants
NCT07788014
A Phase 1 Study of Single and Multiple Ascending Doses of GV-100
Adelaide · Gilva Therapeutics Inc.
Registry updated 26 Aug 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 16 Feb 2026
Ages 18 to 80All sexes105 participants
NCT07285122
Inhaled RB042 in Healthy Adult Volunteers, Healthy Adult Smokers and Patients With Chronic Obstructive Pulmonary Disease
Nedlands · Atisama Therapeutics
Registry updated 12 Aug 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 1 Dec 2025
Ages 18 to 65All sexes84 participants
NCT07235384
A Phase 1/1b Study to Evaluate Safety, Tolerability and Pharmacokinetics of ZL-1503 in Healthy Volunteers and Participants With Moderate to Severe Atopic Dermatitis
Woolloongabba, Carlton · Zai Lab (Shanghai) Co., Ltd.
Registry updated 7 Aug 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 28 Aug 2025
Ages 18 to 55All sexes92 participants
NCT07156201
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ABS-1230 Given Orally Compared With Placebo in Healthy Participants Aged 18 to 55 Years
Sydney · Actio Biosciences, Inc.
Registry updated 7 Aug 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 4 Nov 2025
Ages 18 to 65All sexes96 participants
NCT07245368
Study of PRA-216 in Healthy Participants and Participants With Mild-to-Moderate Asthma
Joondalup, Botany, Nedlands, Clayton, Camberwell · Prana Therapies Inc
Registry updated 6 Aug 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 8 Sept 2023
Ages 18 to 70All sexes168 participants
NCT05945537
A Study of INI-822 in Healthy Volunteers and Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH) or Presumed MASH
Campbelltown, Westmead, Mandurah, Newcastle, Saint Leonards, Woolloongabba, Box Hill, Bedford Park · Inipharm Australia Pty Ltd
Registry updated 3 Aug 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 24 Feb 2026
Ages 18 to 75All sexes60 participants
NCT07284797
A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune Diseases
Melbourne · Xencor, Inc.
Registry updated 3 Aug 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 16 Apr 2026
Ages 18 to 55All sexes64 participants
NCT07527221
Safety and Tolerability of ZE74-0282 in Healthy Volunteers
Randwick · Eilean Therapeutics AU Pty Ltd
Registry updated 28 Jul 2026
Registry record: ClinicalTrials.gov
Phase 2/3Starts 22 Nov 2024
From age 18All sexes280 participants
NCT05552157
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Melbourne, Randwick · Washington University School of Medicine
Registry updated 27 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 7 Apr 2025
Ages 18 to 65All sexes166 participants
NCT06714006
Phase 1 Study to Evaluate the Safety and Tolerability of Intravenously Administered PYC-003
Southport, Westmead, Liverpool, Concord, Joondalup, Wahroonga, South Brisbane, Randwick · PYC Therapeutics
Registry updated 27 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 16 Oct 2025
Ages 18 to 65All sexes72 participants
NCT07184502
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ZT003 Injection Following Single and Multiple Subcutaneous Administration in Healthy Volunteers/Overweight or Obese Volunteers
Brisbane, Melbourne · Beijing QL Biopharmaceutical Co.,Ltd
Registry updated 27 Jul 2026
Registry record: ClinicalTrials.gov
Phase 2/3Starts 22 Nov 2024
From age 18All sexes280 participants
NCT06647498
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Melbourne, Randwick · Washington University School of Medicine
Registry updated 27 Jul 2026
Registry record: ClinicalTrials.gov
No phaseStarts 21 Mar 2024
From age 50Women only1230 participants
NCT05946044
The Osteoarthritis Prevention Study
Sydney · Wake Forest University
Registry updated 23 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 24 Oct 2024
Ages 18 to 100All sexes232 participants
NCT06649110
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Camperdown, Adelaide, New Lambton Heights, Darlinghurst · Novartis Pharmaceuticals
Registry updated 21 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 1 Aug 2025
Ages 18 to 65All sexes100 participants
NCT07085507
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VT7208 in Healthy Participants and MS Patients
Adelaide · Vidya Therapeutics Inc
Registry updated 21 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 9 Apr 2025
Ages 18 to 65All sexes64 participants
NCT06917742
A Study of Intravenous CPTX2309 in Healthy Participants and Participants With Moderate to Severe Rheumatoid Arthritis (RA) or Systemic Lupus Erythematosus (SLE)
Bayswater, Herston, Nedlands · Capstan Therapeutics
Registry updated 16 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 30 Jun 2026
Ages 18 to 55All sexes46 participants
NCT07660341
SAD Study of CGB3002 in Healthy Participants
Melbourne · ChainGen Biopharma Ltd
Registry updated 8 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 8 May 2025
Ages 18 to 80All sexes286 participants
NCT06944925
A Study of BBT002 in Healthy Volunteers (HVs) and in Adult Patients With Chronic Obstructive Pulmonary Disease (COPD) or Chronic Rhiosininusitis With Nasal Polyps (CRSwNP)
Brisbane, Perth · Bambusa Therapeutics
Registry updated 1 Jul 2026
Registry record: ClinicalTrials.gov
Early Phase 1Starts 3 Aug 2025
Ages 1 to 21All sexes15 participants
NCT06333899
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
South Brisbane, Randwick, Perth · Nationwide Children's Hospital
Registry updated 29 Jun 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 19 May 2026
Ages 18 to 65All sexes88 participants
NCT07473323
Evaluation of MTX-439 in Healthy Adults and Adults With Diabetic Kidney Disease
Melbourne · Mediar Therapeutics
Registry updated 29 Jun 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 15 Jun 2026
Ages 18 to 80All sexes100 participants
NCT07581431
A Phase 1, Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISM8969
Melbourne · InSilico Medicine Hong Kong Limited
Registry updated 22 Jun 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 7 Aug 2023
From age 18All sexes50 participants
NCT05876312
Safety, Tolerability, PK and PD of ADX-038 in Healthy Participants and Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients
Melbourne, Parkville, Brisbane · ADARx Pharmaceuticals, Inc.
Registry updated 16 Jun 2026
Registry record: ClinicalTrials.gov
Early Phase 1Starts 1 Jun 2026
Ages 18 to 55All sexes72 participants
NCT07577817
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CTX001 in Healthy Adults.
Melbourne · Cajal Therapeutics Inc.
Registry updated 12 Jun 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 4 Oct 2024
Ages 18 to 70All sexes148 participants
NCT06625671
A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants
Melbourne · DualityBio Inc.
Registry updated 2 Jun 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 13 Jun 2024
Ages 18 to 65All sexes96 participants
NCT06324604
Safety, Pharmacokinetics, and Pharmacodynamics of MTX-101 in Healthy Adults and Patients
Heidelberg, Fitzroy, Melbourne · Mozart Therapeutics Australia Pty Ltd
Registry updated 18 May 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 8 Apr 2026
Ages 18 to 55All sexes48 participants
NCT07526519
A Safety and Pharmacokinetics Study of TL-003 in Healthy Adults and Open-label Assessments in Participants With Ulcerative Colitis
Perth · TrueLab Biopharmaceutical Co., Ltd
Registry updated 15 May 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 28 Apr 2026
Ages 26 to 65All sexes57 participants
NCT07454291
A Study to Evaluate Pharmacokinetics and Drug-drug Interactions of ENV-101 (Taladegib) in Healthy Participants
Brisbane, Melbourne · Endeavor Biomedicines, Inc.
Registry updated 15 May 2026
Registry record: ClinicalTrials.gov
Phase 3Starts 23 Mar 2026
All sexes600 participants
NCT06526533
RECOMMEND Platform Trial
Sydney, Melbourne, Camperdown · Australian and New Zealand Intensive Care Research Centre
Registry updated 13 May 2026
Registry record: ClinicalTrials.gov
No phaseStarts 27 Aug 2025
Ages 18 to 70All sexes530 participants
NCT07055542
Creating A Risk Assessment Tool for Thunderstorm Asthma: the CARISTA Study
Heidelberg, Clayton, Parkville, Albury, Box Hill, Melbourne · University of Melbourne
Registry updated 6 May 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 2025
From age 18All sexes1000 participants
NCT07555574
Defining Retinal Structures Using Hyperspectral Retinal Imaging
Melbourne · Center for Eye Research Australia
Registry updated 29 Apr 2026
Registry record: ClinicalTrials.gov
Phase 3Starts 23 Feb 2026
From age 18All sexes1900 participants
NCT07280065
REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool
Carlton · Senseye, Inc.
Registry updated 29 Apr 2026
Registry record: ClinicalTrials.gov
No phaseStarts 11 Oct 2021
From age 30All sexes930 participants
NCT07545473
Retinal Hyperspectral Imaging in Neurodegenerative Diseases
Melbourne · Center for Eye Research Australia
Registry updated 22 Apr 2026
Registry record: ClinicalTrials.gov
Phase 2Starts 14 Apr 2025
From age 2All sexes104 participants
NCT06510699
Pharmacogenomics for Better Treatment of Fungal Infections Clinical Trial
Melbourne, South Brisbane, Sydney, Brisbane, Adelaide · The University of Queensland
Registry updated 16 Apr 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 30 Dec 2025
Ages 18 to 65All sexes60 participants
NCT06891287
An Early Phase Study of RT-114 (RaniPill Containing PG-102, a GLP-1/2 Dual Agonist) in Healthy Volunteers.
Melbourne · RANI Therapeutics
Registry updated 14 Apr 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 12 Mar 2026
Ages 18 to 65All sexes60 participants
NCT07347678
Phase 1a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RN5681 in Healthy Volunteers
Brisbane, Melbourne · Ikaria Bioscience Pty Ltd
Registry updated 3 Apr 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Feb 2026
Ages 50 to 74Women only1500 participants
NCT07491081
EARLY Study: Evaluating the Specificity and Feasibility of the EARLY Biomarker Panel for Ovarian Cancer Detection
Brisbane · Queensland Centre for Gynaecological Cancer
Registry updated 24 Mar 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 13 Mar 2026
Ages 18 to 65All sexes76 participants
NCT07371455
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LWP779 in Healthy Participants
Adelaide · Longwood Pharmaceuticals (Hangzhou) Co., Ltd.
Registry updated 20 Mar 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 2 Dec 2025
Ages 18 to 60All sexes48 participants
NCT07248865
A Phase 1 Study of CLYM116 in Normal Healthy Volunteers
Brisbane · Climb Bio, Inc.
Registry updated 20 Feb 2026
Registry record: ClinicalTrials.gov
No phaseStarts 26 Nov 2025
From age 18All sexes30 participants
NCT07387978
A Study to Describe the Effect of Photobiomodulation (Low Level Laser Therapy) in Reducing the Severity and Incidence of Oral Mucositis (Oral Ulceration) in Oral Cancer Patients Undergoing Radiation Treatment
Melbourne · Peter MacCallum Cancer Centre, Australia
Registry updated 4 Feb 2026
Registry record: ClinicalTrials.gov
No phaseStarts 18 Oct 2023
Ages 40 to 70All sexes748 participants
NCT05366153
Risk-guided Disease managEment Plan to prevEnt CAD in Patients Treated With Previous Cancer
Melbourne, Hobart · Baker Heart and Diabetes Institute
Registry updated 4 Dec 2025
Registry record: ClinicalTrials.gov
Phase 1/2Starts 4 Nov 2025
Ages 18 to 65All sexes104 participants
NCT07245771
Phase 1/2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effect on Body Weight of RN3161 as Monotherapy and in Combination With Tirzepatide in Adults With Overweight and Obesity
Melbourne · Ikaria Bioscience Pty Ltd
Registry updated 24 Nov 2025
Registry record: ClinicalTrials.gov
Phase 1Starts 18 Jun 2025
Ages 18 to 60All sexes60 participants
NCT06938269
A Study to Evaluate MWN109 Tablets in Healthy Adult Participants
Bayswater, Adelaide · Shanghai Minwei Biotechnology Co., Ltd
Registry updated 20 Nov 2025
Registry record: ClinicalTrials.gov
No phaseStarts 18 Nov 2021
Ages 50 to 85All sexes820 participants
NCT04983823
Persistent Cardiovascular Effects of COVID-19 Viral Infection Trial (PERCEIVE)
Melbourne · Baker Heart and Diabetes Institute
Registry updated 3 Oct 2025
Registry record: ClinicalTrials.gov
Phase 2Starts 12 Aug 2025
Ages 18 to 60All sexes68 participants
NCT07098663
Food Effect, Efficacy and Safety of MKP10241 in Healthy and Obese Adult Participants, With and Without Diabetes
Bayswater · Mankind Pharma Limited
Registry updated 29 Sept 2025
Registry record: ClinicalTrials.gov
Phase 1Starts 11 Sept 2024
Ages 18 to 55Men only40 participants
NCT05620940
A Clinical Trial to Assess Pharmacokinetic Profiles, Safety and Tolerability of IVL3004 and IVL4002 in Healthy Male Subjects.
Herston · Inventage Lab., Inc.
Registry updated 15 Sept 2025
Registry record: ClinicalTrials.gov
Phase 1Starts 30 Jan 2025
Ages 18 to 65All sexes134 participants
NCT06829563
Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RZ-629 in Healthy Subjects and T2D
Adelaide · Rezubio Pharmaceuticals Co., Ltd.
Registry updated 21 Aug 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Feb 2004
Ages 2 to 45All sexes75000 participants
NCT00097292
TrialNet Pathway to Prevention of T1D
Parkville · University of South Florida
Registry updated 1 Jul 2025
Registry record: ClinicalTrials.gov
No phaseStarts 30 Mar 2023
Ages 40 to 85All sexes685 participants
NCT04962711
Risk-guided Disease Management Plan to Prevent Heart Failure in Patients Treated With Previous Chemotherapy (REDEEM)
Melbourne · Baker Heart and Diabetes Institute
Registry updated 31 May 2025
Registry record: ClinicalTrials.gov
Phase 1Starts 17 Mar 2025
Ages 18 to 50All sexes72 participants
NCT06859853
A Study to Evaluate MWN109 Injection in Healthy Subjects
Melbourne · Shanghai Minwei Biotechnology Co., Ltd
Registry updated 15 Apr 2025
Registry record: ClinicalTrials.gov
Phase 1Starts 21 Mar 2023
From age 16All sexes108 participants
NCT05802264
Study to Assess Amphotericin B Cystetic for Inhalation (ABCI) Doses in Healthy Volunteers & People with Cystic Fibrosis
Westmead, Brisbane, Canberra, Clayton · Cystetic Medicines, Inc.
Registry updated 12 Feb 2025
Registry record: ClinicalTrials.gov
No phaseStarts 27 Apr 2021
Ages 35 to 65Women only30 participants
NCT04869098
Effects of an Evening PROtein PrEload on Metabolic Health in Night ShIfT Workers (PROPENSITy)
Adelaide · University of Adelaide
Registry updated 24 Dec 2024
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 2012
Ages 2 to 95All sexes250000 participants
NCT03441451
The Bariatric Surgery Registry
Melbourne · Monash University
Registry updated 12 Dec 2024
Registry record: ClinicalTrials.gov
No phaseStarts 3 Aug 2023
From age 18All sexes10000 participants
NCT06487130
Virtual perI-/Menopause Registry of AusTrALia
Adelaide · Bespoke Clinical Research
Registry updated 5 Jul 2024
Registry record: ClinicalTrials.gov
No phaseStarts 25 Nov 2023
From age 18All sexes300 participants
NCT06148051
AusCADASIL: An Australian Cohort of CADASIL
Newcastle, Sydney, Melbourne, Brisbane · Perminder Sachdev
Registry updated 8 May 2024
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jul 2012
From age 18All sexes35000 participants
NCT01574053
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
Melbourne, Perth, Parkville, Westmead · CHDI Foundation, Inc.
Registry updated 28 Feb 2024
Registry record: ClinicalTrials.gov
No phaseStarts 2 Feb 2021
From age 18All sexes2500 participants
NCT04739319
Project AMD: Comprehensive Characterisation of Age-Related Macular Degeneration and Its Progression
East Melbourne · Center for Eye Research Australia
Registry updated 9 Feb 2024
Registry record: ClinicalTrials.gov
No phaseStarts 5 Mar 2021
From age 50All sexes3000 participants
NCT05194787
TAS Test: Online Motor-cognitive Tests for Early Detection of Alzheimer's Disease
Hobart · University of Tasmania
Registry updated 30 Oct 2023
Registry record: ClinicalTrials.gov
No phaseStarts 23 Jun 2015
Ages 14 to 23All sexes450 participants
NCT05164328
Prospective Athlete's Heart Study
Melbourne · Universitaire Ziekenhuizen KU Leuven
Registry updated 20 Dec 2021
Registry record: ClinicalTrials.gov
No phaseStarts 19 Feb 2014
From age 8All sexes250 participants
NCT03585153
Multicenter Assessment of the Pancreas in Type 1 Diabetes
Melbourne · Vanderbilt University Medical Center
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 28 May 2026
Ages 18 to 60All sexes50 participants
NCT07505030
To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of LYNC-101 for Injection in Healthy Adult Participants
Adelaide · LyncBio Therapeutics Co., Ltd.
Registry updated 27 Aug 2026
Registry record: ClinicalTrials.gov
No phaseStarts 15 Jul 2025
From age 18All sexes30 participants
NCT06879665
TANDem-2: Closing the Gap to Interventions for TAND
Beverly Hills · Vrije Universiteit Brussel
Registry updated 22 Sept 2025
Registry record: ClinicalTrials.gov

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