For volunteers

Healthy volunteer studies in Brazil

50 open studies in the registries that take healthy volunteers and have a site in Brazil.

No phaseStarts 1 Nov 2026
From age 18All sexes45000 participants
NCT07846319
Evaluation of the Effectiveness of Implementing a Screening Strategy for the Diagnosis of Prediabetes and Type 2 Diabetes Mellitus in Primary Health Care in a Brazilian Municipality
Afogados da Ingazeira, Florianópolis · epHealth
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Dec 2026
Ages 15 to 24All sexes1400 participants
NCT06661356
Peer-led Community-based PrEP Delivery Among Youth in Brazil
São Paulo, Salvador · University of Alabama at Birmingham
Registry updated 13 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Aug 2026
Ages 35 to 59All sexes60 participants
NCT07715461
Effect of macaúba Oil Combined With Green Exercises
Montes Claros, João Pessoa · Federal University of Minas Gerais
Registry updated 20 Jul 2026
Registry record: ClinicalTrials.gov
Phase 3Starts 1 Sept 2026
Ages 18 to 29Men only400 participants
NCT07658976
Duo: A Phase IIIb Individual-Level Randomized Controlled Trial of an Integrated Strategy
Manguinhos · HIV Prevention Trials Network
Registry updated 22 Jun 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jul 2026
Ages 18 to 65All sexes800 participants
NCT07589374
Cf-PWV and TyG Index Study
São José do Rio Preto · Hospital de Base
Registry updated 22 May 2026
Registry record: ClinicalTrials.gov
Phase 2Starts 1 Jul 2026
Ages 18 to 65All sexes32 participants
NCT07052058
Triple-Blind Randomized Clinical Trial of Tocilizumab vs Placebo: Potential Use of an IL-6 Antagonist as an Adjuvant to Standard Treatment for Treatment-Resistant Major Depression in the Brazilian Public Health System (SUS)
Porto Alegre · Hospital de Clinicas de Porto Alegre
Registry updated 15 May 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 1 Jun 2026
Ages 18 to 45All sexes48 participants
NCT07518121
A Bridging Study of Efsubaglutide Alfa in Healthy Adults in Brazil
Valinhos · Shanghai Yinnuo Pharmaceutical Technology Co., Ltd.
Registry updated 8 Apr 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2025
From age 18All sexes1000 participants
NCT07186517
Genetic Variants in Stroke
Palmas, Joinville, Campo Grande, Recife, Porto Alegre, Belo Horizonte, Fortaleza, Belém · Hospital Moinhos de Vento
Registry updated 22 Sept 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2025
Ages 5 to 13All sexes50 participants
NCT07160517
AI Toothbrush and Visual Pedagogy to Improve Oral Hygiene in Children With Autism Spectrum Disorder
Ribeirão Preto · University of Sao Paulo
Registry updated 8 Sept 2025
Registry record: ClinicalTrials.gov
Phase 4Starts 1 Jul 2025
All sexes140 participants
NCT06991426
Effects of CreaSafe® on Kidney, Muscle, and Cardiopulmonary Function in Athletes and COPD Patients
Anápolis · Federal University of São Paulo
Registry updated 28 May 2025
Registry record: ClinicalTrials.gov
No phaseStarts 10 Jun 2025
From age 18All sexes103 participants
NCT06787807
Proteomic Analysis of Patients Undergoing Bariatric Surgery
Recife · Universidade Federal de Pernambuco
Registry updated 22 Jan 2025
Registry record: ClinicalTrials.gov
No phaseStarts 30 Jul 2023
From age 18All sexes60 participants
NCT05871983
Munich Transcatheter Mitral Valve Safety and Effectiveness
São Paulo, Rio de Janeiro · P+F Products + Features GmbH
Registry updated 11 Jul 2023
Registry record: ClinicalTrials.gov
Phase 1/2Starts 10 Oct 2024
Ages 18 to 75All sexes270 participants
NCT06619990
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Campinas, Fortaleza, Macaé, Santo André, Salvador, Caxias do Sul, Votuporanga, Porto Alegre · Xencor, Inc.
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 15 Aug 2024
Ages 12 to 55All sexes161 participants
NCT06546670
A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease
Ribeirão Preto, São Paulo · Novartis Pharmaceuticals
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 6 Mar 2026
From age 65All sexes150 participants
NCT07391436
Use of Wearables for Identifying Factors Associated With Mild Cognitive Impairment and Early-Stage Alzheimer's Disease
Manaus · Getúlio Vargas University Hospital
Registry updated 22 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 21 Oct 2026
Ages 40 to 80All sexes40 participants
NCT07802106
Systemic Biochemical Signature and Functional Quality Index of Calcaneal Bone Marrow Aspirate in Adults Undergoing Foot or Ankle Surgery
Bragança Paulista · Universidade Sao Francisco
Registry updated 22 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2026
Ages 18 to 90All sexes20 participants
NCT07878884
PBMT Associated With a Pulmonary Rehabilitation Program on the Functional Capacity of Patients With COPD
Porto Alegre · Federal University of Health Science of Porto Alegre
Registry updated 16 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 2009
From age 18All sexes700 participants
NCT00869817
Dominantly Inherited Alzheimer Network (DIAN)
São Paulo · Washington University School of Medicine
Registry updated 5 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 28 Jun 2023
All sexes3000 participants
NCT06016946
Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study
Campinas · Friedreich's Ataxia Research Alliance
Registry updated 1 Sept 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Feb 2025
Ages 20 to 45Women only15 participants
NCT06868862
Acute Effects of Isoenergetic HIIE vs. MICE on Key Parameters of Fat Mass Loss in Young Females With Overweight or Obesity
São Paulo · Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Registry updated 31 Aug 2026
Registry record: ClinicalTrials.gov
No phaseStarts 25 May 2026
From age 18Men only3000 participants
NCT07772791
Online Cohort of Sexual and Gender Minorities: Evaluating Digital Interventions to Improve HIV Pre-Exposure Prophylaxis and Antiretroviral Treatment Uptake and Adherence
Rio de Janeiro · Oswaldo Cruz Foundation
Registry updated 19 Aug 2026
Registry record: ClinicalTrials.gov
Phase 4Starts 11 Jul 2024
Ages 18 to 75All sexes120 participants
NCT06374875
Fibrosis Lessens After Metabolic Surgery
São Paulo · The Cleveland Clinic
Registry updated 31 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 24 Oct 2024
Ages 18 to 100All sexes232 participants
NCT06649110
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Porto Alegre · Novartis Pharmaceuticals
Registry updated 21 Jul 2026
Registry record: ClinicalTrials.gov
Phase 4Starts 16 Mar 2026
Ages 12 to 59All sexes477 participants
NCT07087912
Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases
São Paulo · University of Sao Paulo General Hospital
Registry updated 20 Jul 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Feb 2025
From age 18All sexes1000 participants
NCT07066046
Artificial Intelligence-assisted Colonoscopy in the Detection and Characterization of Colorectal Lesions
São Paulo · Instituto do Cancer do Estado de São Paulo
Registry updated 23 Jun 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 2 Sept 2024
Ages 18 to 65All sexes142 participants
NCT06576271
A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants
Salvador, Juiz de Fora, Porto Alegre · GlaxoSmithKline
Registry updated 22 Jun 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 2025
Ages 18 to 120All sexes958 participants
NCT06536348
PARKINSON BRASIL - Database on Motor and Non-Motor Aspects of Parkinson's Disease in Brazil
Uberlândia, Goiânia, Brasília · Federal University of Uberlandia
Registry updated 19 May 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Sept 2025
From age 15All sexes400 participants
NCT07584122
Improving Access to PrEP (HIV Prevention Medication) for People in Underserved Areas of Rio de Janeiro
Rio de Janeiro, Nova Iguaçu · Oswaldo Cruz Foundation
Registry updated 13 May 2026
Registry record: ClinicalTrials.gov
No phaseStarts 28 Oct 2025
From age 18All sexes200 participants
NCT07500415
Doxi-Rio: Study on the Use of Doxycycline to Prevent Sexually Transmitted Infections in Rio de Janeiro
Rio de Janeiro · Oswaldo Cruz Foundation
Registry updated 30 Mar 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Aug 2024
Ages 30 to 50All sexes63 participants
NCT04512456
Cardiovascular Responses to Exercise in People Living With HIV/AIDS: Effects of Exercise Training
Rio de Janeiro · Instituto Nacional de Cardiologia de Laranjeiras
Registry updated 27 Mar 2026
Registry record: ClinicalTrials.gov
No phaseStarts 3 Feb 2026
Ages 16 to 30All sexes1500 participants
NCT07497594
ImPrEP LEN Brasil: Twice-Yearly Lenacapavir for HIV Prevention
São Paulo, Campinas, Nova Iguaçu, Florianópolis, Salvador, Manaus, Rio de Janeiro · Oswaldo Cruz Foundation
Registry updated 27 Mar 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 5 Sept 2024
Ages 25 to 65All sexes24 participants
NCT06898606
Psilocybe Cubensis Mushrooms With or Without Fluoxetine for Refractory Depression
Foz do Iguaçu · Federal University of Latin American Integration
Registry updated 27 Mar 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2024
Ages 40 to 70All sexes50 participants
NCT06579807
Cardiac Rehabilitation and Coronary Artery Disease
Rio de Janeiro · Instituto Nacional de Cardiologia de Laranjeiras
Registry updated 27 Mar 2026
Registry record: ClinicalTrials.gov
No phaseStarts 8 Oct 2025
From age 60Women only20 participants
NCT07444138
Effects of Beetroot Extract on Blood Pressure and Exercise in Hypertensive Older Women
Bauru · São Paulo State University
Registry updated 2 Mar 2026
Registry record: ClinicalTrials.gov
Phase 2Starts 28 Apr 2022
From age 18Men only47 participants
NCT04704505
Bipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant Prostate Cancer (mCRPC)
Porto Alegre · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Registry updated 6 Feb 2026
Registry record: ClinicalTrials.gov
No phaseStarts 18 Oct 2024
From age 18All sexes70 participants
NCT07314268
ATTR Amyloid Cardiomyopathy: Characterization of Extracellular Vesicles as Potential Disease Stratifiers and Prognostic Biomarkers
São Paulo · University of Sao Paulo General Hospital
Registry updated 2 Jan 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Sept 2025
Ages 18 to 40Women only20 participants
NCT07159880
Letrozole Extended vs Traditional Therapy for Ovulation Induction in Women With PCOS (PROLEx-PCOS)
São Paulo · GABRIEL MONTEIRO PINHEIRO
Registry updated 28 Nov 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Nov 2019
From age 60All sexes60 participants
NCT04126785
High-Intensity Interval Versus Moderate-Intensity Continuous Water Based Exercise in Hypertensive Older Individuals
Bauru · Universidade Estadual Paulista Júlio de Mesquita Filho
Registry updated 25 Jul 2025
Registry record: ClinicalTrials.gov
Phase 4Starts 1 Apr 2024
From age 18All sexes350 participants
NCT06934798
Inotropic Effects of Vasopressin Versus Noradrenaline In Patients With Vasoplegic Syndrome After Cardiac Surgery
São Paulo · University of Sao Paulo
Registry updated 30 Apr 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Aug 2024
Ages 50 to 80All sexes66 participants
NCT06900270
Comparative of Plasma Proteomics & Metabolomics in Coronary Artery Disease: Obstructive,Non-Obstructive, & No Lesions
São Paulo · University of Sao Paulo General Hospital
Registry updated 28 Mar 2025
Registry record: ClinicalTrials.gov
No phaseStarts 9 Jul 2018
Ages 18 to 59Women only45 participants
NCT03574103
Chronic Effect of Fasting
Belo Horizonte · Federal University of Minas Gerais
Registry updated 18 Mar 2025
Registry record: ClinicalTrials.gov
No phaseStarts 21 Jul 2023
From age 18All sexes1694 participants
NCT05822193
Incidence, Associated Factors, and Burden of Post COVID-19 Condition in Brazil
Cachoeirinha · Inova Medical
Registry updated 19 Feb 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 2025
From age 18All sexes30 participants
NCT06785233
Endoscopic Treatment of Overweight and Mild Obesity with ORBERA365
Santo André · Kaiser Clinic and Hospital
Registry updated 21 Jan 2025
Registry record: ClinicalTrials.gov
No phaseStarts 2 Dec 2024
From age 50All sexes40 participants
NCT06733714
Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults
Rio de Janeiro · Universidade Federal do Rio de Janeiro
Registry updated 13 Dec 2024
Registry record: ClinicalTrials.gov
No phaseStarts 15 Feb 2024
From age 18All sexes40 participants
NCT06248151
Acute Cardiovascular Responses to a Single Exercise Session in Patients With Post-COVID-19 Syndrome
São Paulo · University of Nove de Julho
Registry updated 4 Dec 2024
Registry record: ClinicalTrials.gov
No phaseStarts 27 Aug 2024
Ages 18 to 85All sexes80 participants
NCT06450327
Resistant Hypertension An Open, Complicated ("Cum Plicare") or Complex ("Cum Plexus") Syndrome?
Votuporanga · University of Campinas, Brazil
Registry updated 29 Aug 2024
Registry record: ClinicalTrials.gov
Phase 4Starts 29 May 2017
Ages 18 to 59All sexes400 participants
NCT03132311
Immunogenicity and Safety of the Yellow Fever Vaccine in HIV Infected Individuals
Rio de Janeiro · Oswaldo Cruz Foundation
Registry updated 30 Jul 2018
Registry record: ClinicalTrials.gov
No phaseStarts 24 Jul 2024
Ages 18 to 60All sexes12 participants
NCT07415811
Spironolactone and XPB-1 Integrity in the TFIIH Complex
São Paulo · University of Sao Paulo General Hospital
Registry updated 17 Feb 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 2026
All sexes1342 participants
NCT07295587
Assessment of the Impact of Headache on the Employee Population of Libbs Pharmaceutical Ltd
São Paulo · Libbs Farmacêutica LTDA
Registry updated 19 Dec 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 2024
Ages 18 to 70Women only34 participants
NCT07162311
Effect of Home-Based Transcranial Direct Current Stimulation on Pain in Patients With Rheumatoid Arthritis With Low Inflammatory Activity
Porto Alegre · Federal University of Rio Grande do Sul
Registry updated 9 Sept 2025
Registry record: ClinicalTrials.gov

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