For volunteers

Healthy volunteer studies in Germany

147 open studies in the registries that take healthy volunteers and have a site in Germany.

No phaseStarts 15 Oct 2026
All sexes50 participants
NCT07888322
Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and Prostate
München, Berlin · Aristotle University Of Thessaloniki
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 21 Oct 2026
Ages 25 to 69All sexes121 participants
NCT07896109
A Research Study to Check the Safety of NNC9836-0001 When Given to Healthy Participants and Participants With Type 2 Diabetes
Neuss · Novo Nordisk A/S
Registry updated 26 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2026
From age 18All sexes20 participants
NCT07886502
Upper Airway Morphology and Physiology During Graded Positive Pressure and Nasal High Flow: An MRI Study
Dortmund · Klinikum Dortmund Wirbelsäulenchirurgie
Registry updated 21 Oct 2026
Registry record: ClinicalTrials.gov
Phase 3Starts 1 Dec 2026
Ages 12 to 35All sexes586 participants
NCT07434973
Stratification and Treatment in Early Psychosis Study - PROMOTE
Lübeck, München, Cologne, Berlin · University of Oxford
Registry updated 8 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 5 Feb 2026
From age 18All sexes44 participants
2025-520978-18-00
A Participant- and Investigator--Blinded, Placebo-Controlled, Randomized, Multipart, Single and Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants with Chronic Kidney Disease
Berlin · Novartis Pharma AG
Registry updated 20 Jul 2026
Registry record: EU CTIS
Phase 2Starts 1 Dec 2025
From age 18All sexes228 participants
2022-501137-23-00
A Phase 2 Trial Evaluating the Effects of Thiethylperazine as diagnostic tool and therapeutic agent in Patients Diagnosed with an Early Stage of Alzheimer's disease
Essen, Hanover, Göttingen, Munich, Mannheim, Rostock, Ulm · Immungenetics AG
Registry updated 8 Dec 2025
Registry record: EU CTIS
Phase 2Starts 1 Jan 2026
Ages 18 to 75All sexes27 participants
NCT07214064
Venetoclax- Augmented Treosulfan-Based Reduced Intensity Conditioning Before Allogeneic Stem Cell Transplantation
Tuebingen · University Hospital Tuebingen
Registry updated 9 Oct 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2025
From age 18All sexes50 participants
NCT05238623
Imbalances of Regional Pulmonary Ventilation in Patients With Post-acute-COVID-19
Jena · Jan-Christoph Lewejohann
Registry updated 25 Sept 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jul 2025
From age 7All sexes2720 participants
NCT07011368
Empowering Healthy Lifestyle Personalised Intervention to Prevent and Control Obesity: The HealthyW8 Project
Kaiserslautern, Bremen · Fundació d'investigació Sanitària de les Illes Balears
Registry updated 1 Jul 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jun 2025
From age 45All sexes100 participants
NCT07009990
Coronary and Cerebral Microvascular Dysfunction in Neurological Diseases
Greifswald · University Medicine Greifswald
Registry updated 8 Jun 2025
Registry record: ClinicalTrials.gov
No phaseStarts 30 Jan 2025
From age 18All sexes100 participants
NCT06817915
This Project At LMU Looks At How Using AI 2nd Opinion Report to Analyze Retinal Eye Scans Impact Doctors' Decisions About Treatment for Patients with a Specific Eye Disease (nAMD)
Munich · Johannes Schiefelbein
Registry updated 10 Feb 2025
Registry record: ClinicalTrials.gov
No phaseStarts 15 Oct 2022
Ages 18 to 70All sexes950 participants
NCT05547711
Prediction and Validation of Unipolar Depression With Psychosocial-somatic Markers in a Naturalistic Cohort Recruited in an Outpatient Setting
Munich · Julia Eder
Registry updated 21 Sept 2022
Registry record: ClinicalTrials.gov
No phaseStarts 12 May 2025
From age 50All sexes1000 participants
NCT06924021
Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)
Bonn · University of Wisconsin, Madison
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jul 2026
From age 3All sexes180 participants
NCT07705178
More Than Just X-Rays - Imaging of Chemotherapy-induced Morphological and Functional Cardiovascular and Lung Changes After Childhood ALL and Other Cancers - a Monocentric Late Effects Study (MaximALL)
Erlangen · University of Erlangen-Nürnberg Medical School
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 18 Sept 2020
Ages 18 to 90All sexes20000 participants
NCT04970056
Pancreatic Cancer Early Detection Consortium
Essen · Arbor Research Collaborative for Health
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 26 Oct 2026
Ages 40 to 75All sexes300 participants
NCT07888257
LIfestyle MEtabotype Study B (LIME-B)
Nuthetal, Berlin · German Institute of Human Nutrition
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.gov
Phase 4Starts 30 May 2024
Up to age 17All sexes2365 participants
2023-507348-35-00
Anti-viral action against Type 1 diabetes autoimmunity GPPAD-05-AVAnT1A
Munich, Hanover, Dresden · Klinikum rechts der Isar der TU Muenchen AöR
Registry updated 22 Oct 2026
Registry record: EU CTIS
Phase 1Starts 30 Nov 2023
Ages 18 to 75All sexes106 participants
NCT07630545
A Phase I Study in Healthy Volunteers and Parkinson's Disease (PD) Patients.
Dresden · Mission Therapeutics
Registry updated 20 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 31 Aug 2026
From age 18All sexes54 participants
2026-525271-57-00
A research study looking into how a single dose of the medicine NNC0537-1482 moves through the body of participants with normal or reduced kidney function
Berlin · Novo Nordisk A/S
Registry updated 19 Oct 2026
Registry record: EU CTIS
Phase 1Starts 27 Aug 2024
Ages 30 to 80All sexes124 participants
NCT06565195
A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease
Muenster, Duesseldorf · Prevail Therapeutics
Registry updated 16 Oct 2026
Registry record: ClinicalTrials.gov
No phaseStarts 10 Oct 2026
Ages 40 to 75All sexes300 participants
NCT07868601
LIfestyle MEtabotype Study A
Potsdam · German Institute of Human Nutrition
Registry updated 9 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 5 Nov 2025
From age 18All sexes86 participants
2025-521315-39-00
EAST-1 (ERAP-inhibition in Axial Spondyloarthritis Trial-1)
Herne · Grey Wolf Therapeutics Limited
Registry updated 6 Oct 2026
Registry record: EU CTIS
No phaseStarts 1 Jan 2009
From age 18All sexes700 participants
NCT00869817
Dominantly Inherited Alzheimer Network (DIAN)
Munich, Tübingen · Washington University School of Medicine
Registry updated 5 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 31 Mar 2025
Ages 18 to 64Men only82 participants
2024-513116-10-00
Randomized, double-blind, placebo-controlled Phase I study in healthy individuals on autotaxin-inhibition with MJK2134025 in single-ascending, as well as multiple intravenous doses
Mainz · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR
Registry updated 2 Oct 2026
Registry record: EU CTIS
No phaseStarts 28 Oct 2025
Ages 55 to 75All sexes76 participants
NCT07383311
Autophagy-Enhancers to Reduce Sleep Disturbances
Greifswald · University Medicine Greifswald
Registry updated 2 Oct 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 13 May 2026
Ages 18 to 64All sexes72 participants
2025-524043-12-00
A study to learn more about the safety and effects of a new blood-thinning medicine, given alone and together with another blood-thinner, in healthy adults
Berlin · Bayer AG
Registry updated 1 Oct 2026
Registry record: EU CTIS
No phaseStarts 31 Aug 2026
Ages 18 to 65All sexes75 participants
NCT07691736
Combining Fasting and Fibre Interventions to Optimise Their Gut Microbiome-mediated Health Benefits
Überlingen · Buchinger Wilhelmi Development & Holding GmbH
Registry updated 30 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 16 May 2025
Ages 18 to 64All sexes124 participants
NCT06945406
A Study of LY4057996 in Healthy Participants and Participants With Type 1 and Type 2 Diabetes
Neuss · Eli Lilly and Company
Registry updated 29 Sept 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2025
Ages 18 to 75All sexes30 participants
NCT07171281
Precise Eating Time to Improve Glycemic Control and Cardiometabolic Health in Prediabetes and Diabetes
Nuthetal · German Institute of Human Nutrition
Registry updated 29 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 23 Oct 2025
Ages 18 to 64Men only30 participants
NCT07220564
A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A
Berlin, Bonn, Hanover · Novo Nordisk A/S
Registry updated 18 Sept 2026
Registry record: ClinicalTrials.gov
Phase 2Starts 12 Nov 2024
From age 18All sexes30 participants
2023-508668-31-00
A pilot study of the safety and tolerability of oral administration of PD L 506 and the subsequent diagnostic value of porphyrin concentration (coproporphyrin I / III, CP I / III) in urine in patients with the first occurrence of colorectal cancer and in healthy subjects.
Munich, Essen · Photonamic GmbH & Co. KG
Registry updated 18 Sept 2026
Registry record: EU CTIS
No phaseStarts 1 May 2024
From age 18All sexes40 participants
NCT06494826
Decoding the Clinical Impact of Host and Microbial Intestinal Proteomic Landscape in Crohn's Disease
Hamburg · Weizmann Institute of Science
Registry updated 15 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 27 Jul 2026
Ages 18 to 75All sexes188 participants
NCT07702890
A Three-part First-in-human Trial to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GUB-UCN2 in Healthy Lean and Obese Participants and Participants With T2D
Neuss · Gubra A/S
Registry updated 10 Sept 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Aug 2020
Ages 18 to 65All sexes140 participants
NCT03911726
Do Antipsychotic Agents Induce Supersensitivity in Humans: A Combined PET/MRI Study in Patients With Schizophrenia
Mannheim · Central Institute of Mental Health, Mannheim
Registry updated 8 Sept 2026
Registry record: ClinicalTrials.gov
No phaseStarts 31 May 2024
From age 18All sexes400 participants
NCT06409624
Association Between Biomarkers and Kidney Function Decline in Pulmonary Hypertension
Giessen, Bad Nauheim · University of Giessen
Registry updated 8 Sept 2026
Registry record: ClinicalTrials.gov
No phaseStarts 8 May 2025
From age 18Women only385 participants
NCT06912477
Endothelial Dysfunction for Prognosis In Patients With preeClampSia
Heidelberg · Heidelberg University
Registry updated 4 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 18 Sept 2025
From age 18All sexes89 participants
2024-513613-12-00
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Berlin, Heidelberg, Giessen, Greifswald, Dresden, Wuppertal, Hamburg, Homburg · Novartis Pharma AG
Registry updated 4 Sept 2026
Registry record: EU CTIS
No phaseStarts 21 Aug 2025
From age 18Women only1430 participants
NCT07106294
Hyperspectral Imaging for Prediction of Preeclampsia
Heidelberg · Heidelberg University
Registry updated 4 Sept 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 9 Feb 2026
Ages 18 to 65All sexes67 participants
NCT07392372
A Clinical Trial Investigating the Safety and Biological Activity of the Antibody BNT351 in Adults Living Without and With HIV
Mannheim, Cologne · BioNTech SE
Registry updated 1 Sept 2026
Registry record: ClinicalTrials.gov
No phaseStarts 28 Jun 2023
All sexes3000 participants
NCT06016946
Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study
Aachen, Bonn, Tübingen, Munich · Friedreich's Ataxia Research Alliance
Registry updated 1 Sept 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 May 2023
Ages 0 to 80All sexes1000 participants
NCT05928169
Determinants of Chronic Inflammatory Skin Disease Trajectories
Kiel · University Hospital Schleswig-Holstein
Registry updated 28 Aug 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 27 Oct 2025
Ages 18 to 64All sexes80 participants
2025-521658-40-00
A first-in-human, dose finding study to evaluate the safety, tolerability and pharmacokinetics of EGL-003 in healthy volunteers followed by adults with autoimmune disease.
Dresden, Berlin, Mainz, Bad Bentheim · Egle Therapeutics
Registry updated 28 Aug 2026
Registry record: EU CTIS
No phaseStarts 21 Apr 2026
From age 18All sexes384 participants
NCT07788729
Social Prescriptions and Micro-Learning to Improve Care for Cancer Patients and Their Support Persons
Regensburg, Erlangen, Cologne, Würzburg, Bayreuth, Berlin, Augsburg · University of Regensburg
Registry updated 26 Aug 2026
Registry record: ClinicalTrials.gov
No phaseStarts 20 Jul 2026
Ages 21 to 85All sexes120 participants
NCT07719660
Wearable Blood-Pressure Monitoring Comparison Study
Dresden · Technische Universität Dresden
Registry updated 26 Aug 2026
Registry record: ClinicalTrials.gov
No phaseStarts 3 May 2023
From age 18All sexes128 participants
NCT06954636
Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational Study
Essen, Münster · Sied Kebir
Registry updated 24 Aug 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 27 Aug 2026
From age 18All sexes104 participants
2025-525042-22-00
A Study to Evaluate the Safety and Activity of an Inhaled Investigational Drug (RO7616605) in Healthy Volunteers and Participants With COPD
Berlin, Hanover · Genentech Inc.
Registry updated 24 Aug 2026
Registry record: EU CTIS
No phaseStarts 25 Jun 2025
Ages 1 to 45All sexes30000 participants
NCT07118098
INNODIA Family & Friends Early-Stage T1D Detection Protocol
Greifswald · INNODIA iVZW
Registry updated 24 Aug 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 10 Sept 2024
Ages 18 to 64All sexes140 participants
2024-514853-31-00
A STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF COR-1389
Neuss · Corteria Pharmaceuticals
Registry updated 20 Aug 2026
Registry record: EU CTIS
No phaseStarts 15 May 2026
From age 21All sexes400 participants
NCT07631767
Shift Workers' Health Behavior Action Program Across Europe
Bremerhaven, Bremen · Wageningen University
Registry updated 20 Aug 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 20 Nov 2025
Ages 18 to 65All sexes112 participants
NCT07235059
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney Disease
Berlin · Novartis Pharmaceuticals
Registry updated 19 Aug 2026
Registry record: ClinicalTrials.gov
Early Phase 1Starts 9 Jul 2026
Ages 18 to 60Men only88 participants
NCT07721597
A Single and Multiple Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP6590 in Participants With Normal Weight, Overweight and Obesity
Neuss · Zealand Pharma
Registry updated 13 Aug 2026
Registry record: ClinicalTrials.gov
Early Phase 1Starts 29 Jul 2026
Ages 50 to 75All sexes9 participants
NCT07640542
Test-retest Trial With [11C]MODAG-005 in PD or MSA and AMHC - Pilot Phase
Tübingen · MODAG GmbH
Registry updated 31 Jul 2026
Registry record: ClinicalTrials.gov
No phaseStarts 10 Apr 2025
Ages 1 to 14All sexes400 participants
NCT06943469
Effect of Partially Hydrolyzed Formula With Synbiotics on Skin Barrier Function
Berlin, Spandau, Düsseldorf, Wesel, Frankfurt · Société des Produits Nestlé (SPN)
Registry updated 30 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 3 Aug 2026
Ages 18 to 64All sexes64 participants
2024-514744-91-00
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of ATX304
Neuss · Betagenon AB
Registry updated 30 Jul 2026
Registry record: EU CTIS
Phase 2/3Starts 22 Nov 2024
From age 18All sexes280 participants
NCT06647498
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Tübingen, Munich · Washington University School of Medicine
Registry updated 27 Jul 2026
Registry record: ClinicalTrials.gov
Phase 2/3Starts 22 Nov 2024
From age 18All sexes280 participants
NCT05552157
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Munich, Tübingen · Washington University School of Medicine
Registry updated 27 Jul 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jul 2020
From age 30All sexes4500 participants
NCT04477785
PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
Kassel, Hessen, Lübeck, Tübingen · Michael J. Fox Foundation for Parkinson's Research
Registry updated 27 Jul 2026
Registry record: ClinicalTrials.gov
No phaseStarts 15 Jul 2026
From age 18All sexes160 participants
NCT07726420
HEARTBEAT-TROP. Polyethylene Glycol Precipitation to Unmask Macrotroponin
Munich · Technical University of Munich
Registry updated 24 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1/2Starts 24 Oct 2024
Ages 18 to 100All sexes232 participants
NCT06649110
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Greifswald, Dresden, Berlin, Regensburg, Heidelberg, Homburg, Giessen · Novartis Pharmaceuticals
Registry updated 21 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 25 Nov 2025
Ages 18 to 64All sexes60 participants
NCT07270731
A Research Study of a New Medicine, NNC9733-0001, in Healthy Participants and Participants With Type 2 Diabetes
Neuss · Novo Nordisk A/S
Registry updated 20 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 24 Jun 2026
Ages 18 to 70All sexes115 participants
NCT07665879
A Study of Eloralintide (LY3841136) in Participants With Overweight or Obesity
Neuss · Eli Lilly and Company
Registry updated 16 Jul 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 9 Feb 2024
From age 18All sexes112 participants
2023-507547-11-00
A randomized, double-blind, placebo-controlled, single and multiple-dose-escalation, phase 1 study in healthy volunteers and patients with ulcerative colitis to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of GRT-001 (MONOlith trial)
Berlin · Granite Bio AG
Registry updated 14 Jul 2026
Registry record: EU CTIS
Phase 1Starts 17 Jun 2026
Ages 18 to 55All sexes32 participants
NCT07656454
A Study Understanding How Much CDR132L Enters the Bloodstream After Injection Under the Skin Compared to Injection Into a Vein in Healthy Participants
Berlin · Novo Nordisk A/S
Registry updated 30 Jun 2026
Registry record: ClinicalTrials.gov
Early Phase 1Starts 3 Aug 2025
Ages 1 to 21All sexes15 participants
NCT06333899
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
Heidelberg · Nationwide Children's Hospital
Registry updated 29 Jun 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 2 Dec 2025
Ages 18 to 75All sexes141 participants
NCT07258849
A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis
Berlin · Eli Lilly and Company
Registry updated 23 Jun 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 31 Jan 2025
From age 18All sexes78 participants
2024-517547-31-00
A placebo-controlled, single-blind, phase I study in healthy volunteers and patients with Rheumatoid Arthritis with ABO21009
Frankfurt Am Main, Erlangen · Aboleris Holdco
Registry updated 15 Jun 2026
Registry record: EU CTIS
No phaseStarts 22 Sept 2025
From age 18All sexes126 participants
NCT07580612
AID-FOG: Artificial Intelligence-Driven Freezing of Gait Detection in the Home
Hamburg · KU Leuven
Registry updated 12 May 2026
Registry record: ClinicalTrials.gov
No phaseStarts 6 May 2026
Ages 14 to 49Women only200 participants
NCT07553676
Multicenter Study for Diagnostic Validation of a Laboratory Test for the Diagnosis of Endometriosis
Karlsruhe, Regensburg · Diamens FlexCo
Registry updated 11 May 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Feb 2011
Ages 1 to 90All sexes500 participants
NCT01893710
International (Pediatric) Peritoneal Biobank
Heidelberg, Essen, Marburg, Cologne, Berlin, Hamburg · Heidelberg University
Registry updated 30 Apr 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 26 Feb 2025
Ages 18 to 65All sexes149 participants
NCT07558668
A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis
Freiburg im Breisgau, Berlin, Frankfurt · Sitryx Therapeutics Ltd
Registry updated 30 Apr 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 2017
Ages 11 to 75All sexes2500 participants
NCT02855476
HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease
Münster, Erlangen, Ulm, Dresden, Taufkirchen, Bochum · University College, London
Registry updated 27 Apr 2026
Registry record: ClinicalTrials.gov
No phaseStarts 5 Dec 2022
Ages 18 to 49All sexes2300 participants
NCT05732623
Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
Wuppertal, Munich · San Raffaele University
Registry updated 24 Apr 2026
Registry record: ClinicalTrials.gov
No phaseStarts 4 Jan 2024
Ages 18 to 40Women only75 participants
NCT06130371
Stress, Inflammation and Neuroimaging in Major Depressive Disorder as Compared to Premenstrual Dysphoric Disorder
Tübingen · University Hospital Tuebingen
Registry updated 7 Apr 2026
Registry record: ClinicalTrials.gov
No phaseStarts 15 Feb 2026
From age 18All sexes150 participants
NCT07515521
Enhanced Vision and Imaging Tests for Enabling Treatment Trials in Early and Intermediate AMD
Bonn · Maximilian Pfau
Registry updated 7 Apr 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2025
From age 18All sexes1250 participants
NCT07212699
Development of an Outcome Score for Patients With Knee Osteoarthritis and Knee Joint Endoprosthesis Using an App
Munich · Technical University of Munich
Registry updated 6 Apr 2026
Registry record: ClinicalTrials.gov
No phaseStarts 19 Mar 2026
Ages 35 to 60Women only120 participants
NCT07501377
Effects of a 6-months Fiber- and Polyphenol-rich Diet on Brain Inflammatory Processes in Perimenopausal Women Living With Overweight or Obesity
Leipzig · Max Planck Institute for Human Cognitive and Brain Sciences
Registry updated 30 Mar 2026
Registry record: ClinicalTrials.gov
No phaseStarts 26 Jul 2023
Ages 18 to 65All sexes165 participants
NCT05909267
Dopamine Modulation of Motivation and Motor Function in Major Depression & Inflammation
Steglitz · Charite University, Berlin, Germany
Registry updated 18 Mar 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2025
From age 18All sexes5200 participants
NCT06900829
#AWARE.HIV Europe: Supporting Healthcare Professionals to Find Undiagnosed HIV in European Hospitals: An Effectiveness-implementation Trial.
Berlin, München, Cologne · Casper Rokx
Registry updated 12 Mar 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jun 2025
From age 60All sexes400 participants
NCT07466394
COGSCREEN II: Early Detection of Cognitive Impairment
München · Robert Perneczky
Registry updated 12 Mar 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Nov 2024
Ages 18 to 79All sexes837 participants
NCT07426991
Cognitive Performance, Sleep Disturbances and Fatigue in Multiple Sclerosis
Düsseldorf, Mönchengladbach · Heinrich-Heine University, Duesseldorf
Registry updated 6 Mar 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 2026
Ages 50 to 80All sexes150 participants
NCT07374705
Disentangling the Effect of Brain Insulin Resistance on Brain Health
Ulm · Henrik Bo Wiberg Larsson
Registry updated 25 Feb 2026
Registry record: ClinicalTrials.gov
No phaseStarts 14 May 2025
From age 12All sexes200 participants
NCT07416513
Digital Solutions for bEtter cAre
Homburg · European Institute of Oncology
Registry updated 18 Feb 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 May 2025
Ages 18 to 80All sexes140 participants
NCT07402356
VR Pupillometry in Cognitive Impairment
München · Max-Planck-Institute of Psychiatry
Registry updated 17 Feb 2026
Registry record: ClinicalTrials.gov
No phaseStarts 10 May 2022
From age 18All sexes135 participants
NCT04849806
Sympathetic Nerve Activity Predictors in Patients With Chronic Obstructive Pulmonary Disease
Aachen · RWTH Aachen University
Registry updated 28 Jan 2026
Registry record: ClinicalTrials.gov
Phase 1Starts 9 Feb 2026
Ages 18 to 55All sexes519 participants
NCT07358156
A Study to Compare the Pharmacokinetics, Pharmacodynamic, Immunogenicity, and Safety of CKD-706 With US-Dupixent®, and EU-Dupixent® in Healthy Adult Participants.
Berlin · Chong Kun Dang Pharmaceutical
Registry updated 23 Jan 2026
Registry record: ClinicalTrials.gov
No phaseStarts 1 Dec 2025
Ages 18 to 75All sexes64 participants
NCT07359664
OCTA in Cardiovascular Disease and Healthy Controls
Erlangen · University of Erlangen-Nürnberg Medical School
Registry updated 22 Jan 2026
Registry record: ClinicalTrials.gov
No phaseStarts 4 Dec 2025
Ages 50 to 80All sexes130 participants
NCT07324330
Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity
Bonn · University Hospital, Bonn
Registry updated 16 Jan 2026
Registry record: ClinicalTrials.gov
No phaseStarts 15 May 2025
All sexes14250 participants
NCT06282016
Risk Factors for Neuroendocrine Neoplasms
Nuremberg · Bavarian Cancer Registry
Registry updated 7 Jan 2026
Registry record: ClinicalTrials.gov
No phaseStarts 15 Nov 2016
From age 18All sexes6000 participants
NCT04444128
IMPRoving Cardiovascular RiSk Stratification Using T1 Mapping in General populatION
Frankfurt am Main · Johann Wolfgang Goethe University Hospital
Registry updated 6 Jan 2026
Registry record: ClinicalTrials.gov
No phaseStarts 10 Oct 2025
Ages 18 to 60All sexes120 participants
NCT07198100
tVNS, Motivation, and Insulin Sensitivity
Bonn · University of Bonn
Registry updated 24 Dec 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2024
From age 18All sexes1834 participants
NCT06920680
ColoReg: A Register for Gastrointestinal Endoscopy Reports and Examination Videos
Würzburg, Stuttgart · Wuerzburg University Hospital
Registry updated 22 Dec 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Mar 2024
From age 18All sexes7000 participants
NCT06280755
Clinical Impact Through AI-assisted MS Care - A Retrospective Multi-center Observational Study.
Berlin, Bochum · icometrix
Registry updated 12 Dec 2025
Registry record: ClinicalTrials.gov
No phaseStarts 5 May 2021
From age 18All sexes80 participants
NCT04838249
Effects of Cross-sex Hormone Therapy on Eating Behavior, Metabolism, Energy Balance and Cardiovascular System
Leipzig · University of Leipzig
Registry updated 5 Dec 2025
Registry record: ClinicalTrials.gov
Phase 4Starts 8 May 2024
Ages 3 to 4All sexes2252 participants
NCT06452654
Anti-viral Action Against Type 1 Diabetes Autoimmunity
Munich, Dresden, Hanover · Technical University of Munich
Registry updated 23 Sept 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jun 2021
Ages 50 to 99All sexes2000 participants
NCT04724941
Prodromal Alpha-Synuclein Screening in Parkinson's Disease Study
Kiel · University Hospital Schleswig-Holstein
Registry updated 22 Sept 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Apr 2025
From age 18All sexes120 participants
NCT07150000
Clinical Assessment for Rheumatologic Disease - Research and Advancement in Safety and Efficacy
Bonn · University of Bonn
Registry updated 2 Sept 2025
Registry record: ClinicalTrials.gov
No phaseStarts 9 Dec 2024
From age 18All sexes340 participants
NCT06731673
Heat Shock Protein 47 in Thrombosis
Berlin · University of Aarhus
Registry updated 21 Aug 2025
Registry record: ClinicalTrials.gov
No phaseStarts 8 May 2024
From age 18All sexes400 participants
NCT06887283
Essen Amyloidosis Registry
Essen · University Hospital, Essen
Registry updated 21 Aug 2025
Registry record: ClinicalTrials.gov
No phaseStarts 16 Mar 2015
Ages 0 to 100All sexes1000 participants
NCT03361215
Disease Trajectories and Anti-cytokine Response Signatures in Atopic Dermatitis and Psoriasis
Kiel · University Hospital Schleswig-Holstein
Registry updated 22 Jul 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Sept 2005
Ages 18 to 69All sexes2000 participants
NCT01055093
Prospective Study on Diabetes Mellitus and Its Complications in Newly Diagnosed Adult Patients
Düsseldorf · German Diabetes Center
Registry updated 16 Jul 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Feb 2023
From age 50All sexes300 participants
NCT06711952
German Validation Study of the Subjective Cognitive Decline Questionnaire (SCD-Q)
München · Ludwig-Maximilians - University of Munich
Registry updated 29 May 2025
Registry record: ClinicalTrials.gov
No phaseStarts 14 Sept 2024
From age 18Women only1250 participants
NCT06962670
Predicting Cancer Risk With Digital and Molecular Markers
Please Refer to Project Homepage For Details (see Link Below) · University of Erlangen-Nürnberg Medical School
Registry updated 8 May 2025
Registry record: ClinicalTrials.gov
No phaseStarts 15 Nov 2024
From age 50Men only500 participants
NCT06696027
AYLo - AutoimmunitY and Loss of y
Bonn · University of Bonn
Registry updated 10 Apr 2025
Registry record: ClinicalTrials.gov
No phaseStarts 5 Nov 2024
From age 18All sexes64 participants
NCT06621394
The Effect of Mediterranean Diet and Mindfulness Eating on Depression Severity in People With Obesity and Major Depressive Disorder
Stuttgart · University Hospital Tuebingen
Registry updated 8 Apr 2025
Registry record: ClinicalTrials.gov
No phaseStarts 30 Jan 2020
All sexes40000 participants
NCT05329714
PVRI GoDeep Global Deep Phenotyping Meta-Registry for Pulmonary Hypertension
Giessen · University of Giessen
Registry updated 4 Apr 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jul 2024
Ages 18 to 70All sexes60 participants
NCT06487832
Effect of GLP1 Receptor Agonist on Brain Insulin Responsiveness
Tübingen · University Hospital Tuebingen
Registry updated 30 Mar 2025
Registry record: ClinicalTrials.gov
No phaseStarts 17 Mar 2021
From age 18All sexes5000 participants
NCT05521451
Clinical Cohort Study - TRUST
Hamburg · Universitätsklinikum Hamburg-Eppendorf
Registry updated 30 Mar 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jun 2023
Ages 18 to 80All sexes250 participants
NCT06885255
Effects of Intermittent Fasting and Exercise on Inflammation, Metabolism, and the Microbiome in Metabolic Syndrome
Erlangen · University of Erlangen-Nürnberg Medical School
Registry updated 20 Mar 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2021
Ages 18 to 80All sexes600 participants
NCT04655235
Translational Investigation of the Glutamatergic and GABAergic System in Schizophrenia
Aachen, Gangelt · RWTH Aachen University
Registry updated 14 Mar 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Sept 2019
Ages 8 to 18All sexes90 participants
NCT04066465
Neurocognitive Function After Proton Therapy in Children and Adolescents
Dresden · Technische Universität Dresden
Registry updated 6 Feb 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Sept 2012
Ages 20 to 70All sexes450 participants
NCT01477957
The Effect of Bariatric Surgery on Insulin Sensitivity and Energy Metabolism
Düsseldorf · German Diabetes Center
Registry updated 10 Jan 2025
Registry record: ClinicalTrials.gov
No phaseStarts 1 Feb 2015
Ages 2 to 10All sexes285000 participants
NCT04039945
Fr1da Early Diagnosis and Care of Type 1 Diabetes
Munich · Helmholtz Zentrum München
Registry updated 17 Dec 2024
Registry record: ClinicalTrials.gov
No phaseStarts 19 Oct 2017
Ages 1 to 6All sexes1000000 participants
NCT03316261
Freder1k-Study - Testing Infants for Type 1 Diabetes Risk
Munich · Helmholtz Zentrum München
Registry updated 17 Dec 2024
Registry record: ClinicalTrials.gov
No phaseStarts 28 Nov 2024
From age 18All sexes40 participants
NCT06716892
Non-invasive Preoperative Tissue Evaluation in Head and Neck Tumor Patients Using Multispectral Optoacoustic Tomography (MSOT)
Erlangen · University of Erlangen-Nürnberg Medical School
Registry updated 4 Dec 2024
Registry record: ClinicalTrials.gov
No phaseStarts 1 Aug 2024
Ages 18 to 60All sexes50 participants
NCT06389968
Light Stimulation to Improve Visual Function After Optic Neuritis in Persons with Multiple Sclerosis
Munich · Technical University of Munich
Registry updated 22 Nov 2024
Registry record: ClinicalTrials.gov
No phaseStarts 31 Jan 2023
Ages 15 to 25Women only380 participants
NCT06642831
Polycystic Ovarian Syndrome (PCOS) Biomarker Evaluation Study
Erlangen · University Hospital Erlangen
Registry updated 15 Oct 2024
Registry record: ClinicalTrials.gov
No phaseStarts 1 Dec 2022
All sexes3000 participants
NCT06621810
Artificial Intelligence Based Melanoma Early Diagnosis and Risk Prediction in Children, Adolescents and Young Adults
Tübingen · German Cancer Research Center
Registry updated 1 Oct 2024
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jul 2024
Ages 18 to 80All sexes50 participants
NCT06330818
Imaging in Moyamoya Disease - Study to Investigate Different Imaging Technologies for a Better Understanding of Various Imaging Techniques to Evaluate Cerebral Hemodynamics, Disease-activity and Possibly the Etiology in Moyamoya Patients
Tübingen · University Hospital Tuebingen
Registry updated 26 Sept 2024
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 2013
Ages 6 to 18All sexes1500 participants
NCT02496468
Pediatric Arm of DZL All Age Asthma Cohort
Marburg, Lübeck, Hanover, Munich, Cologne · LMU Klinikum
Registry updated 28 Aug 2024
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 2013
Ages 18 to 50Women only100 participants
NCT05010902
Pregnancy Cohort in Multiple Sclerosis (MS)
Berlin · Charite University, Berlin, Germany
Registry updated 5 Jul 2024
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jun 2013
Ages 18 to 85All sexes3000 participants
NCT05442970
Cohort Study for Atrial Fibrillation Risk Stratification
Hamburg · Universitätsklinikum Hamburg-Eppendorf
Registry updated 13 May 2024
Registry record: ClinicalTrials.gov
No phaseStarts 23 Feb 2024
From age 18All sexes150 participants
NCT06208007
Arterial Stiffening as a Predictor for Diastolic Cardiac Dysfunction and HFpEF
Göttingen · University Medical Center Goettingen
Registry updated 9 May 2024
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2020
From age 18All sexes75 participants
NCT04700358
Characterization of Antibacterial Antibodies in Patients With Cystic Fibrosis
Cologne · University Hospital of Cologne
Registry updated 8 May 2024
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jul 2012
From age 18All sexes35000 participants
NCT01574053
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
Lübeck, Erlangen, Münster, Freiburg im Breisgau, Taufkirchen, Berlin, Aachen, Dresden · CHDI Foundation, Inc.
Registry updated 28 Feb 2024
Registry record: ClinicalTrials.gov
No phaseStarts 1 Dec 2021
From age 18All sexes250 participants
NCT05192655
Artificial Intelligence in Functional Imaging for Individualized Treatment of Head and Neck Squamous Cell Carcinoma Patients
Berlin · Charite University, Berlin, Germany
Registry updated 7 Feb 2024
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2017
From age 18All sexes200 participants
NCT03240965
Changes in Sensitivity, Taste and Smell in Stroke Patients
Giessen · University of Giessen
Registry updated 1 Dec 2023
Registry record: ClinicalTrials.gov
No phaseStarts 31 Mar 2021
From age 18All sexes20000 participants
NCT05561504
Helicobacter Pylori Local Prevalence and Antibiotic Resistance
Munich · Technical University of Munich
Registry updated 30 Nov 2023
Registry record: ClinicalTrials.gov
No phaseStarts 20 Oct 2023
Ages 20 to 65All sexes40 participants
NCT06039787
Exercise Training on Brain Insulin Responsiveness
Tübingen · University Hospital Tuebingen
Registry updated 8 Nov 2023
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 2002
Ages 1 to 18All sexes3000 participants
NCT04491344
Leipzig Childhood Obesity Study
Leipzig · University of Leipzig
Registry updated 7 Nov 2023
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 1998
Up to age 18All sexes1000000 participants
NCT03072537
CrescNet - Growth Monitoring Network
Leipzig · University of Leipzig
Registry updated 7 Nov 2023
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2010
All sexes1000 participants
NCT02208141
Leipzig Adipose Tissue Childhood Cohort
Leipzig · University of Leipzig
Registry updated 7 Nov 2023
Registry record: ClinicalTrials.gov
No phaseStarts 1 Mar 2014
Ages 18 to 99All sexes400 participants
NCT02419274
Adult Arm of DZL All Age Asthma Cohort (ALLIANCE)
Großhansdorf · LungenClinic Grosshansdorf
Registry updated 12 Oct 2023
Registry record: ClinicalTrials.gov
No phaseStarts 30 Dec 2018
Ages 18 to 80All sexes300 participants
NCT05046483
Metabolic Phenotyping and Follow-Up of Patients With and Without Diabetes After New Onset of STEMI
Düsseldorf · German Diabetes Center
Registry updated 22 Aug 2023
Registry record: ClinicalTrials.gov
No phaseStarts 26 Jan 2017
All sexes2000 participants
NCT03052283
Development and Validation of a Disease Specific PROM to Assess Abdominal Involvement in Patients With CF (CFAbd-Score)
Brandenburg an der Havel · Medizinische Hochschule Brandenburg Theodor Fontane
Registry updated 4 Apr 2023
Registry record: ClinicalTrials.gov
No phaseStarts 1 Sept 2003
From age 18All sexes10000 participants
NCT01789229
Establishment of a Tumor Bank for Tissue Samples
Berlin · Medical University of Vienna
Registry updated 23 Mar 2023
Registry record: ClinicalTrials.gov
No phaseStarts 1 Nov 2003
From age 18All sexes10000 participants
NCT01763125
Establishment of a Tumor Bank for Blood Samples
Freiburg im Breisgau, Berlin, Herne · Medical University of Vienna
Registry updated 23 Mar 2023
Registry record: ClinicalTrials.gov
No phaseStarts 8 Mar 2022
Ages 18 to 60All sexes90 participants
NCT05353504
Impact of Microbiome-changing Interventions on Food Decision-making
Leipzig · Max Planck Institute for Human Cognitive and Brain Sciences
Registry updated 29 Apr 2022
Registry record: ClinicalTrials.gov
No phaseStarts 8 Feb 2016
Ages 45 to 74All sexes45000 participants
NCT03934957
Hamburg City Health Study - a German Cohort Study
Hamburg · Universitätsklinikum Hamburg-Eppendorf
Registry updated 2 May 2019
Registry record: ClinicalTrials.gov
No phaseStarts 26 Sept 2017
Ages 18 to 45Women only1580 participants
NCT03313024
Berlin-Brandenburg Pregnancy Cohort
Berlin · Charite University, Berlin, Germany
Registry updated 14 Aug 2018
Registry record: ClinicalTrials.gov
No phaseStarts 1 Apr 2015
From age 18All sexes10000 participants
NCT02149004
German Centre for Infection Research HIV Translational Platform
Cologne · University Hospital of Cologne
Registry updated 27 Oct 2017
Registry record: ClinicalTrials.gov
No phaseStarts 1 Jan 1995
From age 1All sexes100000 participants
NCT01821456
Cologne Cohort of Neutropenic Patients (CoCoNut)
Cologne · University Hospital of Cologne
Registry updated 1 Apr 2013
Registry record: ClinicalTrials.gov
No phaseStarts 15 Jan 2020
Ages 45 to 100Men only1000 participants
NCT06872619
RegisterPROS - A Registry for Prostate Cancers
Münster · Wren Laboratories LLC
Registry updated 21 Aug 2026
Registry record: ClinicalTrials.gov
No phaseStarts 27 Aug 2025
From age 18All sexes22 participants
NCT07529041
Real-time Acoustic Biofeedback for Enhancing Fixation Stability: A Proof-of-concept Study to Improve Ophthalmic Imaging Diagnostic Quality
Göttingen · University Medical Center Goettingen
Registry updated 14 Apr 2026
Registry record: ClinicalTrials.gov
No phaseStarts 8 Apr 2025
Ages 18 to 40All sexes60 participants
NCT06954844
tVNS and Obesity-related Mechanisms
Bonn · University of Bonn
Registry updated 2 May 2025
Registry record: ClinicalTrials.gov
No phaseStarts 21 May 2024
Ages 18 to 55All sexes80 participants
NCT06389175
Non-invasive Vagus Nerve Stimulation as a Tool to Modulate Stomach-Brain Coupling in Depression
Bonn · University of Bonn
Registry updated 4 Dec 2024
Registry record: ClinicalTrials.gov
No phaseStarts 1 Oct 2018
From age 18All sexes300 participants
NCT04066608
Prevalence of Advanced Fibrosis in Patients Living With HIV
Mainz · Johannes Gutenberg University Mainz
Registry updated 28 Dec 2023
Registry record: ClinicalTrials.gov
No phaseStarts 2 May 2018
From age 18All sexes500 participants
NCT03388476
Endtidal Carbon Dioxide for Earlier Detection of Pulmonary Hypertension
Giessen · University of Giessen
Registry updated 19 May 2022
Registry record: ClinicalTrials.gov

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