Coronary artery disease: trials for referral
1533 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Where the open trials are
Type a city to sort by distance. The distance is worked out in your browser; the city is not sent anywhere.
400 trials shown · Showing the 400 most recently updated of 1533 open trials.
No phase1 site
By invitation onlyUnited States
NCT06374498
Study to Determine the Clinical Significance of Intravascular OCT-NIRAF
Massachusetts General Hospital
Registry updated 10 Nov 2026
Registry record: ClinicalTrials.govNo phase0 sites
Not yet recruiting
NCT07928583
To Evaluate The Efficacy And Safety Of Rivaroxaban In Combination With Aspirin Compared With Aspirin Monotherapy In Patients With Stable Coronary Artery Disease (CAD) and High Ischemic Risk
Republican Specialized Scientific and Practical Medical Center of Cardiology
Registry updated 10 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingCanada
NCT06217120
Reversing Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction
Montreal Heart Institute
Registry updated 10 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingFrance
NCT05211401
Rituximab in Patients With ST-elevation Myocardial Infarction
Assistance Publique - Hôpitaux de Paris
Registry updated 10 Nov 2026
Registry record: ClinicalTrials.govPhase 323 sites
RecruitingUnited States
NCT07232069
PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis
Duke University
Registry updated 10 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingUnited States
NCT07839936
A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease
Verve Therapeutics, Inc.
Registry updated 10 Nov 2026
Registry record: ClinicalTrials.govNo phase18 sites
RecruitingUnited States
NCT06445608
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm
Kardion Inc
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 49 sites
Not yet recruitingNorway
NCT07854795
Reconsidering Long-Term Apirin in the Elderly in Secondary Prevention of Coronary Artery Disease Norway
Vestre Viken Hospital Trust
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingGermany
NCT07762560
Routine Microaxial Heart Pump Support and Protocolized Pulmonary Artery Catheter Monitoring Versus Standard Care in Heart Attack-Related Cardiogenic Shock
Leipzig Heart Science gGmbH
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govNo phase16 sites
RecruitingFrance
NCT07545512
ODSSEY-SCD_Identification Of Markers to preDict the rISk of Sudden Cardiac Death in Moderated LVEF in ischEmic cardiomyopathY
University Hospital, Clermont-Ferrand
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 33 sites
RecruitingCanada
NCT07524335
Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Controlled Trial
Montreal Heart Institute
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 41 site
Not yet recruitingChina
NCT07912801
Roxadustat and Myocardial Injury After Off-Pump Coronary Artery Bypass Surgery
Peking University First Hospital
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govPhase 41 site
RecruitingUnited States
NCT07225842
The Bridging Antiplatelet Therapy With Cangrelor 2 Study
University of Florida
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govEarly Phase 11 site
RecruitingUnited States
NCT06326996
Thiamine Intervention and Coronary Artery Bypass Grafting
University of California, Los Angeles
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingChina
NCT07920133
Hs-CRP-Guided Colchicine Treatment Targets in Very-High-Risk Patients With Coronary Artery Disease After PCI (TARGET-CHD)
Sir Run Run Shaw Hospital
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 41 site
RecruitingSouth Korea
NCT07684742
Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary Syndrome
Gyeongsang National University Hospital
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingChina
NCT07920055
Sirolimus-Coated Versus Paclitaxel-Coated Balloon for Recurrent Coronary In-Stent Restenosis After Prior Paclitaxel-Coated Balloon Treatment (SPRIT)
Sir Run Run Shaw Hospital
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govNo phase23 sites
RecruitingAustria, Switzerland, Germany, France, Poland, United States
NCT06779630
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Teleflex
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingSouth Korea
NCT07235657
AI-Assisted Interpretation of Cardiac CT in the Emergency Department
Yonsei University
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUruguay
NCT07593157
Invasive Evaluation and Phenotype-Guided Treatment of ANOCA in Women
Hospital de Clínicas Dr. Manuel Quintela
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 28 sites
RecruitingAustralia
NCT07362446
Prevention of Reperfusion Injury Outcomes Through Effective Cardioprotection Targeting Myocardial Infarction
Nyrada Pty Ltd
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govNo phase0 sites
Not yet recruiting
NCT07912541
ADVA ACE Coronary Stent System in Coronary Artery Disease Patients (ADVANCE)
Advanced MedTech Solutions Pvt. Ltd.
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 316 sites
RecruitingFrance
NCT07164859
Safety and Efficacy of Very Short DAPT in Older Patients Undergoing PCI
Vincent ROULE
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingChina
NCT07912671
Out-Patient Proactive Observation With Wearable-Assisted Tracking for Cardiovascular Health Management
China National Center for Cardiovascular Diseases
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT07704918
Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma
University of Colorado, Denver
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govNo phase26 sites
RecruitingUnited States
NCT07296744
Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)
Supira Medical
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 36 sites
RecruitingBelgium, United Kingdom, Netherlands, United States
NCT07357675
A Clinical Trial To Investigate The Effect Of EA-230 On Hospital Length Of Stay In Patients With Coronary Artery Disease (CAD) Undergoing Coronary Artery Bypass Grafting (CABG) Surgery.
EBI Anti Sepsis BV
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govNo phase4 sites
RecruitingAustralia, New Zealand
NCT07510438
AVS Pulse Intravascular Lithotripsy™ (Pulse IVL™) to Open Vessels With Calcific Walls and Enhance Vascular Compliance and Remodeling for Coronary Artery Disease
Amplitude Vascular Systems, Inc.
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govNo phase3 sites
RecruitingBelgium, United Kingdom
NCT06939374
Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With Stable Angina or ACS - A Traditional Feasibility Study
Cryotherapeutics SA
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govPhase 31 site
Not yet recruitingCanada
NCT07908082
Aspirin for the Prevention of Ischemic Complications in Giant Cell Arteritis
Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.gov
The same sites as a list
- China97 open trials
- United States71 open trials
- South Korea36 open trials
- Poland24 open trials
- Germany23 open trials
- Spain23 open trials
- United Kingdom19 open trials
- Canada18 open trials
- France17 open trials
- Switzerland13 open trials
- Australia13 open trials
- Belgium13 open trials
- Netherlands13 open trials
- Italy13 open trials
- Denmark9 open trials
- Austria7 open trials
- Japan7 open trials
- Sweden7 open trials
- Russia7 open trials
- Pakistan6 open trials
- Taiwan6 open trials
- Hungary6 open trials
- Egypt5 open trials
- Brazil5 open trials
- Czechia5 open trials
- Norway4 open trials
- New Zealand4 open trials
- Greece4 open trials
- Türkiye4 open trials
- Israel4 open trials
- Hong Kong3 open trials
- Ireland3 open trials
- Singapore3 open trials
- Romania3 open trials
- Serbia3 open trials
- Bulgaria2 open trials
- Portugal2 open trials
- Argentina2 open trials
- Latvia2 open trials
- Chile2 open trials
- Malaysia2 open trials
- Indonesia2 open trials
- Mexico2 open trials
- Uruguay1 open trial
- Ecuador1 open trial
- India1 open trial
- Uzbekistan1 open trial
- Armenia1 open trial
- Lithuania1 open trial
- Georgia1 open trial
- Puerto Rico1 open trial
- Luxembourg1 open trial
- Croatia1 open trial
- Martinique1 open trial
- Bosnia and Herzegovina1 open trial
- Lebanon1 open trial
- Paraguay1 open trial
- Vietnam1 open trial
- Iran1 open trial
- Nepal1 open trial
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
What changed in the last 7 days
Registry facts, one per line, newest first.
Opened for recruitment
BRIDGE Trial: Embedding Consumer-grade mHealth Technologies Into Cardiac Rehabilitation
NCT07741396 · No phase · United States
Source: ClinicalTrials.govNew in the registry
Reversing Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction
NCT06217120 · Phase 2 · Canada
Source: ClinicalTrials.govOpened for recruitment
A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease
NCT07839936 · Phase 2 · United States
Source: ClinicalTrials.govOpened for recruitment
Inorganic Nitrate as a Treatment for ANOCA: NO-ANOCA
NCT06948201 · No phase · United States
Source: ClinicalTrials.govOpened for recruitment
Telegram Messenger Support for Smoking Cessation After Heart Attack
NCT07230249 · No phase · Russia
Source: ClinicalTrials.govOpened for recruitment
Clinical Information System Impact on Hospitalized Patients With Chronic Disease
NCT07609381 · No phase · Canada
Source: ClinicalTrials.govClosed for recruitment
Effect of Dapagliflozin on Microvascular Function in Women With Symptoms of Coronary Artery Disease
NCT05762952 · Phase 1 · United States
Source: ClinicalTrials.govOpened for recruitment
Preoperative Gastric Ultrasound and Left Ventricular Function in Coronary Artery Bypass Surgery
NCT07898215 · No phase · Türkiye
Source: ClinicalTrials.gov
Show more
Status changed: Running, not recruiting → Completed
Physical Activity Intervention in ELderly Patients With Myocardial INfarction
NCT04183465 · No phase · Italy
Source: ClinicalTrials.govOpened for recruitment
AI-Assisted Interpretation of Cardiac CT in the Emergency Department
NCT07235657 · No phase · South Korea
Source: ClinicalTrials.govOpened for recruitment
Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary Syndrome
NCT07684742 · Phase 4 · South Korea
Source: ClinicalTrials.govNew in the registry
Partial Cardiac Denervation for Preventing Atrial Fibrillation After CABG
NCT07918781 · No phase · China
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
NCT07495813 · Phase 1 · Netherlands
Source: ClinicalTrials.govStatus changed: Completed → Not yet recruiting
NCT07118449 · Phase 2 · Germany, Hungary, Netherlands, Poland, United States
Source: ClinicalTrials.govStatus changed: Completed → Not yet recruiting
NCT06956807 · Phase 1 · Poland
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
NCT05360446 · Phase 3 · Argentina, Australia, Belgium, Brazil, Canada, Switzerland
Source: ClinicalTrials.govClosed for recruitment
NCT07118449 · Phase 2 · Germany, Hungary, Netherlands, Poland, United States
Source: ClinicalTrials.govOpened for recruitment
Invasive Evaluation and Phenotype-Guided Treatment of ANOCA in Women
NCT07593157 · No phase · Uruguay
Source: ClinicalTrials.govNew in the registry
Computational μFR-Guided Versus Angiographic Guidance in Drug-Coated Balloon Angioplasty
NCT07917234 · No phase · Italy
Source: ClinicalTrials.govNew in the registry
A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease
NCT04464655 · No phase · Canada
Source: ClinicalTrials.govClosed for recruitment
Scalable Clinical Oversight of Large Language Models Via Uncertainty Triangulation
NCT07414966 · No phase · China
Source: ClinicalTrials.govClosed for recruitment
Benidipine in Hypertensive and/or Chronic Coronary Syndrome Patients
NCT06808321 · No phase
Source: ClinicalTrials.govNew in the registry
Coronary Myocardial Bridge and Coronary Plaques on MDCT
NCT07916272 · No phase · Egypt
Source: ClinicalTrials.gov
New reviews, guidelines and randomised trials in PubMed
Randomised trial
Cardiovascular diabetology · PubMed
Meta-analysis
BMC cardiovascular disorders · PubMed
Meta-analysis
BMC pediatrics · PubMed
Systematic review
Frontiers in microbiology · PubMed
Meta-analysis
Medicine · PubMed
Systematic review
Reviews in cardiovascular medicine · PubMed
Systematic review
PloS one · PubMed
Meta-analysis
BMC cardiovascular disorders · PubMed
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
No phaseEnded 4 Nov 2026
Completed512 participants
NCT04183465
Physical Activity Intervention in ELderly Patients With Myocardial INfarction
Phase 3Ended 30 Oct 2026
Completed44 participants
NCT07295223
Effect of Glp-1 and Antidiabetic sgLT2 Agents for myoCardial infarcTion and Ultrasensitive Inflammatory Surveillance (GALACTUS Trial)
No phaseEnded 20 Oct 2026
No phaseEnded 17 Oct 2026
Completed90 participants
NCT07823400
MIECC vs Conventional Cardiopulmonary Bypass and Systemic Inflammation in CABG
Phase 3Ended 2 Oct 2026
Completed232 participants
NCT05134012
RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
No phaseEnded 1 Oct 2026
Completed135 participants
NCT07878260
Erectile and Ejaculatory Function Following Coronary Revascularization
No phaseEnded 1 Oct 2026
Completed202 participants
NCT07921758
The Role of Multidimensional Prognostic Index (MPI) in the Assessment of Elderly Patients underGoING Cardiac REHABilitation
No phaseEnded 30 Sept 2026
Completed200 participants
NCT05401240
Using Cardiopulmonary Exercise Test as an Incentive to Outpatient Cardiac Rehabilitation for Acute Coronary Syndrome Survivors.
No phaseEnded 26 Sept 2026
Completed460 participants
NCT04878133
OCT Guided vs COmplete Pci in patieNts With sT Segment Elevation myocArdial infarCtion and mulTivessel Disease
No phaseEnded 4 Sept 2026
No phaseEnded 1 Sept 2026
Completed6000 participants
NCT06570759
Time for a Diagnostic Paradigm Shift From STEMI/NSTEMI to OMI/NOMI
No phaseEnded 1 Sept 2026
Withdrawn before start0 participants
NCT05494151
Metabolic Substrate of Patients With Myocardial Infarction With and Without Modifiable Cardiovascular Risk Factors
Reason given: Due to unforeseen challenges in participant recruitment and retention, the study was early terminated to maintain the integrity of the data and ensure ethical standards were upheld.
No phaseEnded 24 Aug 2026
No phaseEnded 21 Aug 2026
Completed387 participants
NCT07711951
CPB and Aortic Cross-Clamp Durations and ICU Length of Stay After CABG Retrospective Observational Cohort Study
No phaseEnded 18 Aug 2026
Phase 1Ended 17 Aug 2026
No phaseEnded 13 Aug 2026
Completed23 participants
NCT05609214
Complementary Investigation of Perfusion and Anatomy Measures of the Heart With MRI and Combined PET/MRI
No phaseEnded 5 Aug 2026
Completed60 participants
NCT07412795
Non-Surgical Periodontal Therapy and Cardiac Biomarkers in Stable Angina
Phase 4Ended 5 Aug 2026
Completed84 participants
NCT05681702
Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI
Phase 4Ended 5 Aug 2026
Completed637 participants
NCT04654052
VerifyNow to Optimise Platelet Inhibition in Coronary Acute Syndrome
Show more
No phaseEnded 1 Aug 2026
Completed30 participants
NCT07148518
Comparison of Upper and Lower Limb Maximal Exercise Capacities and Arterial Stiffness in Patients With CAD
No phaseEnded 1 Aug 2026
Completed208 participants
NCT07882550
Validation of Cor-IS Impedance Spectroscopy Against Ultrasound Flow-Mediated Dilation
No phaseEnded 31 Jul 2026
Completed24 participants
NCT05600088
Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With (N)STEMI or Unstable Angina
No phaseEnded Jul 2026
Paused350 participants
NCT07464704
Infrasensor for Early Detection of a High-grade Obstructive NSTE-ACS
Reason given: Study enrollment and interventions are temporarily paused due to lack of operational funding. This is not an IRB suspension.
No phaseEnded 31 Jul 2026
Completed200 participants
NCT07855003
Evaluate the Clinical Efficacy and Safety of Non-Compliant PTCA Balloon Dilatation Catheter
No phaseEnded 30 Jul 2026
No phaseEnded 30 Jul 2026
No phaseEnded 26 Jul 2026
Completed45 participants
NCT05426083
Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock
No phaseEnded 25 Jul 2026
No phaseEnded 25 Jul 2026
Completed170 participants
NCT06278519
CARdiAc Mri and BiOLogical samplEs at the Acute Phase of a Myocardial Infarction (CARAMBOLE)
Phase 2Ended 22 Jul 2026
Stopped early3 participants
NCT06700720
YN001-004 in Patients With Coronary Atherosclerosis in Australia
Reason given: The study was terminated at the request of the Sponsor.
Phase 3Ended 16 Jul 2026
Completed8323 participants
NCT04023552
Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With CVD
- Lipoprotein(a) and CKD: Insights into New Therapeutic Opportunities. · Clinical journal of the American Society of Nephrology : CJASN, 2026
- Pelacarsen and Cardiovascular Outcomes in Patients with High Lipoprotein(a). · The New England journal of medicine, 2026
Phase 2Ended 13 Jul 2026
Completed57 participants
NCT06415227
The Impact of Vericiguat on Microvascular Function in Patients With Documented Vasospastic Angina Pectoris
No phaseEnded 10 Jul 2026
No phaseEnded 7 Jul 2026
Completed180 participants
NCT04058990
Safety and Effectiveness of Agent Paclitaxel-Coated PTCA Balloon Catheter. (AGENT Japan SV)
No phaseEnded 7 Jul 2026
No phaseEnded 4 Jul 2026
Phase 2Ended 2 Jul 2026
Completed66 participants
NCT06465303
A Study of RTP-026 to Assess Safety, Tolerability and Efficacy in Patients With ST-Elevation Myocardial Infarction (STEMI)
No phaseEnded 1 Jul 2026
Phase 2Ended 1 Jul 2026
No phaseEnded 1 Jul 2026
Completed600 participants
NCT07866144
Prediction of Adverse Events From Non-PCI Coronary Plaques Using Machine Learning
No phaseEnded 30 Jun 2026
No phaseEnded 30 Jun 2026
Completed489 participants
NCT06939738
Artificial Intelligence Scalable Solution for ST Myocardial Infarction
No phaseEnded 30 Jun 2026
Completed554 participants
NCT05605288
Distal Versus Conventional Transradial Artery Access for Coronary Catheterization in Patients With STEMI
No phaseEnded 30 Jun 2026
Phase 2Ended Jun 2026
Withdrawn before start0 participants
NCT04218786
Effect of Colchicine in Patients With Myocardial Infarction
Reason given: Due to the pandemic, there were logistical issues in continuing the study.
Phase 2Ended 29 Jun 2026
Completed187 participants
NCT06186102
Polyamine Treatment in Elderly Patients With Coronary Artery Disease
- Spermidine and spermine in elderly patients with coronary artery disease: a cross-sectional study of dietary intake and plasma and skeletal muscle concentrations. · Clinical nutrition (Edinburgh, Scotland), 2026
No phaseEnded 29 Jun 2026
Completed277 participants
NCT07763769
Validation of the MedHub AutocathFFR Software Device for Non-Invasive Fractional Flow Reserve (FFR)
Phase 3Ended 11 Jun 2026
No phaseEnded 5 Jun 2026
Completed264 participants
NCT06055972
Impact of Patient-Centered Approach for Communicating Coronary Calcium on Cardiovascular Health
No phaseEnded 1 Jun 2026
Completed120 participants
NCT07581678
Five Multimodal AI Configurations Versus Expert Anaesthesiologists for Classifying Pecto-Intercostal Fascial Plane Block Spread in CABG
No phaseEnded 31 May 2026
Completed200 participants
NCT05285631
Early Prediction of ICD Candidacy After Anterior Myocardial Infarction
No phaseEnded 31 May 2026
Completed377753 participants
NCT07610577
Use and Costs of P2Y12 Inhibitors After Acute Myocardial Infarction
No phaseEnded 30 May 2026
Completed75 participants
NCT07704827
Avatar-Based Serious Game for Cardiac Rehabilitation After Heart Attack
No phaseEnded 30 May 2026
Completed66 participants
NCT07475273
The Effectiveness of Early Mobilisation on Back Pain in Patients Following Percutaneous Coronary Intervention
Phase 4Ended 30 May 2026
Completed602 participants
NCT04981041
Escalated Single Platelet Inhibition for One Month Plus NOAC in Patients With Atrial Fibrillation and ACS Undergoing PCI
No phaseEnded 21 May 2026
Completed80 participants
NCT05072730
ComparIson of Strategies to PrepAre SeveRely CALCified Coronary Lesions 2
Phase 4Ended 16 May 2026
Stopped early119 participants
NCT05613426
Effect of Very Early and Rapid Lowering Cholesterol With Evolocumab on Left Ventricular Remodeling in Patients With Anterior STEMI Undergoing Primary PCI
Reason given: Slow patient enrollment and lack of financial support
No phaseEnded 15 May 2026
No phaseEnded 13 May 2026
Completed150 participants
NCT02445885
Late Reperfusion With Percutaneous Coronary Intervention in Patients With ST-segment Elevation Myocardial Infarction
Not medical advice. fetched 11 Nov 2026